| Embryonic stem cell potency fluctuates with endogenous retrovirus activity TS Macfarlan, WD Gifford, S Driscoll, K Lettieri, HM Rowe, D Bonanomi, ... Nature 487 (7405), 57-63, 2012 | 1115 | 2012 |
| Functional gene correction for cystic fibrosis in lung epithelial cells generated from patient iPSCs AL Firth, T Menon, GS Parker, SJ Qualls, BM Lewis, E Ke, CT Dargitz, ... Cell reports 12 (9), 1385-1390, 2015 | 365 | 2015 |
| Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells AL Firth, CT Dargitz, SJ Qualls, T Menon, R Wright, O Singer, FH Gage, ... Proceedings of the National Academy of Sciences 111 (17), E1723-E1730, 2014 | 266 | 2014 |
| TRP channels in hypertension AL Firth, CV Remillard, JXJ Yuan Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (8), 895-906, 2007 | 160 | 2007 |
| Adenylyl cyclase type 6 deletion decreases left ventricular function via impaired calcium handling T Tang, MH Gao, NC Lai, AL Firth, T Takahashi, T Guo, JXJ Yuan, ... Circulation 117 (1), 61-69, 2008 | 123 | 2008 |
| PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells A Ogawa, AL Firth, KA Smith, MV Maliakal, JXJ Yuan American Journal of Physiology-Cell Physiology 302 (2), C405-C411, 2012 | 116 | 2012 |
| Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition G Carraro, J Langerman, S Sabri, Z Lorenzana, A Purkayastha, G Zhang, ... Nature medicine 27 (5), 806-814, 2021 | 113 | 2021 |
| Pathophysiology of voltage-gated K+ channels in vascular smooth muscle cells: modulation by protein kinases EA Ko, WS Park, AL Firth, N Kim, JXJ Yuan, J Han Progress in biophysics and molecular biology 103 (1), 95-101, 2010 | 110 | 2010 |
| Identification of putative endothelial progenitor cells (CD34+CD133+Flk-1+) in endarterectomized tissue of patients with chronic thromboembolic pulmonary … W Yao, AL Firth, RS Sacks, A Ogawa, WR Auger, PF Fedullo, MM Madani, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 296 (6 …, 2009 | 102 | 2009 |
| Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines NB Woods, AS Parker, R Moraghebi, MK Lutz, AL Firth, KJ Brennand, ... Stem cells 29 (7), 1158-1164, 2011 | 100 | 2011 |
| Idiopathic pulmonary arterial hypertension AL Firth, J Mandel, JXJ Yuan Disease models & mechanisms 3 (5-6), 268-273, 2010 | 100 | 2010 |
| Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis Z Borok, M Horie, P Flodby, H Wang, Y Liu, S Ganesh, AL Firth, P Minoo, ... American Journal of Respiratory and Critical Care Medicine 201 (2), 198-211, 2020 | 95 | 2020 |
| Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels AL Firth, CV Remillard, O Platoshyn, I Fantozzi, EA Ko, JXJ Yuan Pulmonary circulation 1 (1), 48-71, 2011 | 94 | 2011 |
| Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs T Menon, AL Firth, DD Scripture-Adams, Z Galic, SJ Qualls, WB Gilmore, ... Cell stem cell 16 (4), 367-372, 2015 | 85 | 2015 |
| Multipotent mesenchymal progenitor cells are present in endarterectomized tissues from patients with chronic thromboembolic pulmonary hypertension AL Firth, W Yao, A Ogawa, MM Madani, GY Lin, JXJ Yuan American Journal of Physiology-Cell Physiology 298 (5), C1217-C1225, 2010 | 80 | 2010 |
| The anti-diabetic drug dapagliflozin induces vasodilation via activation of PKG and Kv channels H Li, SE Shin, MS Seo, JR An, IW Choi, WK Jung, AL Firth, DS Lee, ... Life sciences 197, 46-55, 2018 | 78 | 2018 |
| Hypoxia divergently regulates production of reactive oxygen species in human pulmonary and coronary artery smooth muscle cells W Wu, O Platoshyn, AL Firth, JXJ Yuan American Journal of Physiology-Lung Cellular and Molecular Physiology 293 (4 …, 2007 | 76 | 2007 |
| Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension A Ogawa, AL Firth, W Yao, MM Madani, KM Kerr, WR Auger, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (4 …, 2009 | 71 | 2009 |
| Establishment of the early cilia preassembly protein complex during motile ciliogenesis A Horani, A Ustione, T Huang, AL Firth, J Pan, SP Gunsten, JA Haspel, ... Proceedings of the National Academy of Sciences 115 (6), E1221-E1228, 2018 | 69 | 2018 |
| Patho-, physiological roles of voltage-dependent K+ channels in pulmonary arterial smooth muscle cells WS Park, AL Firth, J Han, EA Ko Journal of smooth muscle research 46 (2), 89-105, 2010 | 65 | 2010 |
Jason X-J Yuan, MD, PhDProfessor and Director, University of California, San DiegoVerified email at ucsd.edu
