Peculiarities of 2-amino-3-R-4-aryl-4 H-pyranes multicomponent synthesis derived from 1 H-2, 1-benzothiazin-4 (3 H)-one 2, 2-dioxide DA Lega, NY Gorobets, VP Chernykh, SV Shishkina, LA Shemchuk RSC advances 6 (19), 16087-16099, 2016 | 22 | 2016 |
An efficient, three-component synthesis and molecular structure of derivatives of 2-amino-3-R-6-ethyl-4,6-dihydropyrano[3,2-c][2,1]benzothiazine-5,5-dioxide … LA Shemchuk, DA Lega, RG Redkin, VP Chernykh, OV Shishkin, ... Tetrahedron 70 (44), 8348-8353, 2014 | 20 | 2014 |
1, 2-Benzoxathiin-4 (3 H)-one 2, 2-dioxide–new enol nucleophile in three-component interaction with benzaldehydes and active methylene nitriles GV Grygoriv, DA Lega, VP Chernykh, L Zaprutko, AK Gzella, A Pawełczyk, ... RSC advances 8 (65), 37295-37302, 2018 | 11 | 2018 |
Synthesis of 1-ethyl-1H-2,1-benzothiazine 2,2-dioxide derivatives using cycloalkanecarbaldehydes and evaluation of their antimicrobial activity DA Lega, VP Chernykh, L Zaprutko, AK Gzella, LA Shemchuk Chemistry of Heterocyclic Compounds 53, 219-229, 2017 | 11 | 2017 |
The study of the three-component interaction between 1-ethyl-1H-2, 1-benzothiazin-4 (3H)-one 2, 2-dioxide, heterylcarbaldehydes and active methylene nitriles DA Lega, VP Chernykh, LA Shemchuk НФаУ, 2016 | 11 | 2016 |
Synthesis of novel spiro-condensed 2-amino-4H-pyrans based on 1,2-benzoxathiin-4(3H)-one 2,2-dioxide GV Grygoriv, DA Lega, L Zaprutko, AK Gzella, E Wieczorek-Dziurla, ... Chemistry of Heterocyclic Compounds 55, 254-260, 2019 | 9 | 2019 |
The synthesis, anti-inflammatory, analgesic and antimicrobial activities of ethyl 2-amino-4-alkyl-4, 6-dihydropyrano [3, 2c][2, 1] benzothiazin-3-carboxylate 5, 5-dioxides and … DA Lega, NI Filimonova, IA Zupanets, SK Shebeko, VP Chernykh, ... Journal of Organic and Pharmaceutical Chemistry 14 (4 (56)), 3-11, 2016 | 9 | 2016 |
Antimicrobial, anti-inflammatory and analgesic activities of 2-amino-6-ethyl-4, 6-dihydropyrano [3, 2-c][2, 1] benzothiazine 5, 5-dioxides and triethylammonium 3-[1-(4-hydroxy … DA Lega, NI Filimonova, IA Zupanets, SK Shebeko, VP Chernykh, ... News of Pharmacy, 61-69, 2016 | 5 | 2016 |
Synthesis of 1, 2-benzoxathiine 2, 2-dioxide derivatives using aliphatic aldehydes and assessment of their antimicrobial activity GV Grygoriv, DO Lega, VP Chernykh, TP Osolodchenko, LA Shemchuk | 4 | 2017 |
Domino-reactions of 1, 2-benzoxathiin-4 (3H)-one 2, 2-dioxide, hetarenecarbaldehydes and active methylene nitriles in the construction of new 2-amino-4H-pyrans and the study of … GV Grygoriv, DA Lega, VP Chernykh, TP Osolodchenko, LA Shemchuk | 3 | 2018 |
The use of aliphatic aldehydes in the synthesis of new pyran annulated derivatives of 1h-2, 1-benzothiazin-4-one 2, 2-dioxide via domino-type interactions. The antimicrobial … DA Lega, NI Filimonova, OG Geyderikh, VP Chernykh, LA Shemchuk Журнал органічної та фармацевтичної хімії, 29-40, 2016 | 3 | 2016 |
Some Aspects of 4H‐Pyrans Synthesis Based on 4‐Chloro‐1‐ethyl‐1H‐benzo[c][1,2]thiazine‐3‐carbaldehyde 2,2‐dioxide: Antimicrobial Activity of the … TI Kolodyazhna, DA Lega, SY Suikov, AA Kyrylchuk, MV Vovk, ... ChemistrySelect 6 (48), 14005-14012, 2021 | 2 | 2021 |
1, 2-Benzoxathiin-4 (3H)-one 2, 2-dioxide–an underinvestigated building block with a high synthetic and pharmacological potential: synthesis, chemical properties, biological … HV Hryhoriv, DA Lega, LA Shemchuk | 2 | 2021 |
Multi-faceted commercially sourced Pd-Supported Reduction: A View from Practical Experience VV Burianov, DA Lega, VG Makhankova, YM Volovenko, SV Kolotilov, ... | 1 | 2022 |
Spiro [benzo [е] pyrano [3, 2-c][1, 2] oxathiin-4, 3’-indolil]-3-carbonitrile 5, 5-dioxides: synthesis and the biological activity study GV Grygoriv, DA Lega, IA Zupanets, SK Shebeko, SM Zimin, ... | 1 | 2019 |
The synthesis of 2-amino-4-aryl-4H-pyrano [3, 2-c][1, 2] benzoxathiine-3-carbonitrile 5, 5-dioxides and the study of their effect on the blood coagulation process GV Grygoriv, DA Lega, LM Shemchuk, LM Maloshtan, GS Kalenichenko, ... News of Pharmacy, 3-8, 2018 | 1 | 2018 |
Cycloalkanecarbaldehydes in synthesis of novel 1, 2-benzoxathiin-4 (3H)-on 2, 2-dioxide derivatives and study of the antimicrobial activity of synthesized compounds GV Grygoriv, DA Lega, VP Chernykh, TP Osolodchenko, LA Shemchuk | 1 | 2017 |
In vitro antimicrobial activity evaluation of 2-amino-3-r-6-ethyl-4, 6-dihydropyrano [3, 2-c][2, 1] benzothiazine 5, 5-dioxides with 4-aryl substituent and spirofused with 2 … DA Lega, NI Filimonova, HM Dikaya, VP Chernykh, LA Shemchuk Ukrainian biopharmaceutical journal, 24-32, 2016 | 1 | 2016 |
PRACTICAL MULTIGRAM APPROACH TO CONFORMATIONALLY CONSTRAINED PROLINE-BASED BUILDING BLOCKS WITH GAMMA-SPIRO CONJUNCTION I Iermolenko, O Kolosov, E Ostapchuk, D Lega, N Derkach, K Levchenko, ... | | 2024 |
EFFICIENT MULTIGRAM SYNTHESIS OF 3, 3-SPIRO-α-PROLINE CONTAINING CHIMERAS N Derkach, K Levchenko, I Iermolenko, E Ostapchuk, D Lega, ... | | 2024 |