| A novel therapeutic approach to treating obesity through modulation of TGFβ signaling A Koncarevic, S Kajimura, M Cornwall-Brady, A Andreucci, A Pullen, ... Endocrinology 153 (7), 3133-3146, 2012 | 113 | 2012 |
| A soluble activin receptor type IIb prevents the effects of androgen deprivation on body composition and bone health A Koncarevic, M Cornwall-Brady, A Pullen, M Davies, D Sako, J Liu, ... Endocrinology 151 (9), 4289-4300, 2010 | 84 | 2010 |
| Dosage of X‐linked Toll‐like receptor 8 determines gender differences in the development of systemic lupus erythematosus BR Umiker, S Andersson, L Fernandez, P Korgaokar, A Larbi, ... European journal of immunology 44 (5), 1503-1516, 2014 | 64 | 2014 |
| Female bias in systemic lupus erythematosus is associated with the differential expression of X-linked toll-like receptor 8 G McDonald, N Cabal, A Vannier, B Umiker, RH Yin, AV Orjalo Jr, ... Frontiers in immunology 6, 457, 2015 | 36 | 2015 |
| The NLRP3 inflammasome mediates DSS-induced intestinal inflammation in Nod2 knockout mice B Umiker, HH Lee, J Cope, NJ Ajami, JP Laine, C Fregeau, H Ferguson, ... Innate Immunity 25 (2), 132-143, 2019 | 30 | 2019 |
| Production of IgG autoantibody requires expression of activation‐induced deaminase in early‐developing B cells in a mouse model of SLE BR Umiker, G McDonald, A Larbi, CO Medina, E Hobeika, M Reth, ... European journal of immunology 44 (10), 3093-3108, 2014 | 26 | 2014 |
| Expression of an anti‐RNA autoantibody in a mouse model of SLE increases neutrophil and monocyte numbers as well as IFN‐I expression JH Han, BR Umiker, AA Kazimirova, M Fray, P Korgaonkar, E Selsing, ... European journal of immunology 44 (1), 215-226, 2014 | 22 | 2014 |
| Preclinical evaluation of JTX-1811, an anti-CCR8 antibody with enhanced ADCC activity, for preferential depletion of tumor-infiltrating regulatory T cells F Dépis, C Hu, J Weaver, L McGrath, B Klebanov, J Buggé, B Umiker, ... Cancer Research 80 (16_Supplement), 4532-4532, 2020 | 9 | 2020 |
| Inhibition of LILRB2 by a novel blocking antibody designed to reprogram immunosuppressive macrophages to drive T-cell activation in tumors B Umiker, Y Hashambhoy-Ramsay, J Smith, T Rahman, A Mueller, ... Molecular Cancer Therapeutics 22 (4), 471-484, 2023 | 8 | 2023 |
| 217 Evaluating biomarkers of JTX-8064 (anti-LILRB2/ILT4 monoclonal antibody) in an ex vivo human tumor histoculture system to inform clinical development Y Hashambhoy-Ramsay, V Spaulding, M Priess, K O’Malley, M Gostissa, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 2 | 2020 |
| 172P Phase I study of JTX-8064, a LILRB2 (ILT4) inhibitor, as monotherapy and combination with pimivalimab (pimi), a PD-1 inhibitor (PD-1i), in patients (pts) with advanced … K Papadopoulos, T Li, N Lakhani, J Powderly, T George, DGK Teoh, ... Immuno-Oncology and Technology 16, 2022 | 1 | 2022 |
| In vitro gastrointestinal model comprising lamina propria-derived cells SJ Kerns, J Obrigewitch, M Salmon, BR Umiker US Patent App. 17/527,422, 2022 | 1 | 2022 |
| Phase 1, first-in-human trial of JTX-8064, an anti-LILRB2/ILT4 monoclonal antibody, as monotherapy and in combination with anti-PD-1 in adult patients with advanced solid … KP Papadopoulos, NJ Lakhani, TA Yap, AL Naumovski, KS Brown, ... Journal of Clinical Oncology 39 (15_suppl), TPS2672-TPS2672, 2021 | 1 | 2021 |
| 945 Overlapping and distinct patterns of LILRB receptors support complementary targeting approach in cancer J Smith, A Mueller, V Spaulding, M Priess, K Bala, A Dunn, S Jaffe, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
| In vitro gastrointestinal model comprising lamina propria-derived cells SJ Kerns, J Obrigewitch, M Salmon, BR Umiker US Patent 11,230,688, 2022 | | 2022 |
| Tumor associated macrophages and resistance to immune checkpoint blockade: consideration of cancer indications for the clinical development of JTX-8064, an anti-LILRB2/ILT4 … L McGrath, A Mueller, T Rahman, J Smith, M Yore, E Stack, K O'Malley, ... Cancer Research 81 (13_Supplement), 1727-1727, 2021 | | 2021 |
| In vitro gastrointestinal model comprising lamina propria-derived cells SJ Kerns, J Obrigewitch, M Salmon, M Kasendra, BR Umiker US Patent 11,001,795, 2021 | | 2021 |
| Inflamed Intestine-Chip: Mimicking the Mucosal Microenvironment to Understand the Pathogenesis of Ulcerative Colitis SJ Kerns, B Umiker, J Obrigewitch, J Puerta, M Salmon, S Alves, ... Gastroenterology 152 (5), S613, 2017 | | 2017 |
| Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus (BA4P. 216) B Umiker, S Andersson, L Fernandez, P Korgaokar, A Larbi, ... The Journal of Immunology 192 (1_Supplement), 46.7-46.7, 2014 | | 2014 |
| Activation-Induced Deaminase in Early Developing B cells and Toll-like Receptor 8 in the Etiopathology of Murine Systemic Lupus Erythematosus BR Umiker Tufts University-Graduate School of Biomedical Sciences, 2014 | | 2014 |
