| Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism SB Prusiner, AL Woerman, DA Mordes, JC Watts, R Rampersaud, ... Proceedings of the National Academy of Sciences 112 (38), E5308-E5317, 2015 | 728 | 2015 |
| Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions J Stöhr, JC Watts, ZL Mensinger, A Oehler, SK Grillo, SJ DeArmond, ... Proceedings of the National Academy of Sciences 109 (27), 11025-11030, 2012 | 436 | 2012 |
| Transmission of multiple system atrophy prions to transgenic mice JC Watts, K Giles, A Oehler, L Middleton, DT Dexter, SM Gentleman, ... Proceedings of the National Academy of Sciences 110 (48), 19555-19560, 2013 | 434 | 2013 |
| Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II G Kryger, M Harel, K Giles, L Toker, B Velan, A Lazar, C Kronman, ... Acta Crystallographica Section D: Biological Crystallography 56 (11), 1385-1394, 2000 | 394 | 2000 |
| Diagnosis of human prion disease JG Safar, MD Geschwind, C Deering, S Didorenko, M Sattavat, ... Proceedings of the National Academy of Sciences 102 (9), 3501-3506, 2005 | 347 | 2005 |
| Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients JC Watts, C Condello, J Stöhr, A Oehler, J Lee, SJ DeArmond, L Lannfelt, ... Proceedings of the National Academy of Sciences 111 (28), 10323-10328, 2014 | 325 | 2014 |
| Design and construction of diverse mammalian prion strains DW Colby, K Giles, G Legname, H Wille, IV Baskakov, SJ DeArmond, ... Proceedings of the National Academy of Sciences 106 (48), 20417-20422, 2009 | 249 | 2009 |
| Propagation of prions causing synucleinopathies in cultured cells AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, ... Proceedings of the National Academy of Sciences 112 (35), E4949-E4958, 2015 | 241 | 2015 |
| Transmission of elk and deer prions to transgenic mice G Tamgüney, K Giles, E Bouzamondo-Bernstein, PJ Bosque, MW Miller, ... Journal of virology 80 (18), 9104-9114, 2006 | 213 | 2006 |
| Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice J Stöhr, C Condello, JC Watts, L Bloch, A Oehler, M Nick, SJ DeArmond, ... Proceedings of the National Academy of Sciences 111 (28), 10329-10334, 2014 | 186 | 2014 |
| Continuous quinacrine treatment results in the formation of drug-resistant prions S Ghaemmaghami, M Ahn, P Lessard, K Giles, G Legname, ... PLoS pathogens 5 (11), e1000673, 2009 | 172 | 2009 |
| Drug resistance confounding prion therapeutics DB Berry, D Lu, M Geva, JC Watts, S Bhardwaj, A Oehler, AR Renslo, ... Proceedings of the National Academy of Sciences 110 (44), E4160-E4169, 2013 | 152 | 2013 |
| Inactivation of prions by acidic sodium dodecyl sulfate D Peretz, S Supattapone, K Giles, J Vergara, Y Freyman, P Lessard, ... Journal of virology 80 (1), 322-331, 2006 | 150 | 2006 |
| Genes contributing to prion pathogenesis G Tamgüney, K Giles, DV Glidden, P Lessard, H Wille, P Tremblay, ... Journal of General Virology 89 (7), 1777-1788, 2008 | 135 | 2008 |
| Evidence that bank vole PrP is a universal acceptor for prions JC Watts, K Giles, S Patel, A Oehler, SJ DeArmond, SB Prusiner PLoS pathogens 10 (4), e1003990, 2014 | 132 | 2014 |
| Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer’s disease C Condello, T Lemmin, J Stöhr, M Nick, Y Wu, AM Maxwell, JC Watts, ... Proceedings of the National Academy of Sciences 115 (4), E782-E791, 2018 | 123 | 2018 |
| Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease JC Watts, K Giles, SK Grillo, A Lemus, SJ DeArmond, SB Prusiner Proceedings of the National Academy of Sciences 108 (6), 2528-2533, 2011 | 120 | 2011 |
| Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation K Giles, DV Glidden, R Beckwith, R Seoanes, D Peretz, SJ DeArmond, ... PLoS pathogens 4 (11), e1000206, 2008 | 103 | 2008 |
| aCHEdb: the database system for ESTHER, the α/β fold family of proteins and the Cholinesterase gene server X Cousin, T Hotelier, K Giles, J Pierre Toutant, A Chatonnet Nucleic acids research 26 (1), 226-228, 1998 | 85 | 1998 |
| Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein JC Watts, K Giles, J Stöhr, A Oehler, S Bhardwaj, SK Grillo, S Patel, ... Proceedings of the National Academy of Sciences 109 (9), 3498-3503, 2012 | 83 | 2012 |
