Ultra-large library docking for discovering new chemotypes J Lyu, S Wang, TE Balius, I Singh, A Levit, YS Moroz, MJ O’Meara, T Che, ... Nature 566 (7743), 224-229, 2019 | 748 | 2019 |
Phosphorylation of 1‐alkylmidazoles and 1‐alkylbenzimidazoles with phosphorus (III) halides in the presence of bases AA Tolmachev, AA Yurchenko, AS Merculov, MG Semenova, ... Heteroatom Chemistry: An International Journal of Main Group Elements 10 (7 …, 1999 | 145 | 1999 |
Bicyclic conformationally restricted diamines OO Grygorenko, DS Radchenko, DM Volochnyuk, AA Tolmachev, ... Chemical Reviews 111 (9), 5506-5568, 2011 | 113 | 2011 |
Combinatorial knoevenagel reactions SV Ryabukhin, AS Plaskon, DM Volochnyuk, SE Pipko, AN Shivanyuk, ... Journal of Combinatorial Chemistry 9 (6), 1073-1078, 2007 | 105 | 2007 |
N-Substituted ureas and thioureas in Biginelli reaction promoted by chlorotrimethylsilane: Convenient synthesis of N1-alkyl-, N1-aryl-, and N1, N3-dialkyl-3, 4-dihydropyrimidin … SV Ryabukhin, AS Plaskon, EN Ostapchuk, DM Volochnyuk, ... Synthesis 2007 (03), 417-427, 2007 | 101 | 2007 |
Synthesis of fused imidazoles and benzothiazoles from (hetero) aromatic ortho-diamines or ortho-aminothiophenol and aldehydes promoted by chlorotrimethylsilane SV Ryabukhin, AS Plaskon, DM Volochnyuk, AA Tolmachev Synthesis 2006 (21), 3715-3726, 2006 | 94 | 2006 |
Enamine real database: Making chemical diversity real AN Shivanyuk, SV Ryabukhin, A Tolmachev, AV Bogolyubsky, ... Chemistry today 25 (6), 58-59, 2007 | 76 | 2007 |
“Reported, but still unknown.” A closer look into 3, 4-bis-and 3, 4, 5-tris (trifluoromethyl) pyrazoles II Gerus, RX Mironetz, IS Kondratov, AV Bezdudny, YV Dmytriv, ... The Journal of Organic Chemistry 77 (1), 47-56, 2012 | 71 | 2012 |
Sulfonyl fluorides as alternative to sulfonyl chlorides in parallel synthesis of aliphatic sulfonamides AV Bogolubsky, YS Moroz, PK Mykhailiuk, SE Pipko, AI Konovets, ... ACS Combinatorial Science 16 (4), 192-197, 2014 | 66 | 2014 |
Trimethylsilyl-1, 3, 4-oxadiazoles—new useful synthons for the synthesis of various 2, 5-disubstituted-1, 3, 4-oxadiazoles EV Zarudnitskii, II Pervak, AS Merkulov, AA Yurchenko, AA Tolmachev Tetrahedron 64 (45), 10431-10442, 2008 | 66 | 2008 |
Synthesis of quinolines from 3-formylchromone AS Plaskon, SV Ryabukhin, DM Volochnyuk, KS Gavrilenko, ... The Journal of Organic Chemistry 73 (15), 6010-6013, 2008 | 57 | 2008 |
Synthesis of annulated benzimidazoles via amidine cyclization K Liubchak, K Nazarenko, A Tolmachev Tetrahedron 68 (14), 2993-3000, 2012 | 56 | 2012 |
Phosphorylation of imidazo[2,1‐b]thiazoles with phosphorus(III) halides in the presence of bases EV Zarudnitskii, AA Yurchenko, AS Merkulov, MG Semenova, AM Pinchuk, ... Heteroatom Chemistry: An International Journal of Main Group Elements 16 (7 …, 2005 | 56 | 2005 |
Aminoheterocycles as synthons for combinatorial Biginelli reactions SV Ryabukhin, AS Plaskon, SY Boron, DM Volochnyuk, AA Tolmachev Molecular diversity 15, 189-195, 2011 | 55 | 2011 |
Phosphorylation of 2‐(3‐methyl‐1, 3‐diazabuten‐1‐yl)‐3‐ethoxycarbonylthiophenes with phosphorus (III) halides AM Pinchuk, SA Kovalyova, SP Ivonin, AS Merkulov, TN Kudrya, ... Heteroatom Chemistry: An International Journal of Main Group Elements 12 (7 …, 2001 | 55 | 2001 |
[2+2]-Photocycloaddition of N-Benzylmaleimide to Alkenes As an Approach to Functional 3-Azabicyclo[3.2.0]heptanes YA Skalenko, TV Druzhenko, AV Denisenko, MV Samoilenko, ... The Journal of Organic Chemistry 83 (12), 6275-6289, 2018 | 52 | 2018 |
CF3-substituted 1, 3-dicarbonyl compounds in the Biginelli reaction promoted by chlorotrimethylsilane SV Ryabukhin, AS Plaskon, EN Ostapchuk, DM Volochnyuk, OV Shishkin, ... Journal of Fluorine Chemistry 129 (7), 625-631, 2008 | 52 | 2008 |
3-haloquinolines by friedlander reaction of α-haloketones SV Ryabukhin, VS Naumchik, AS Plaskon, OO Grygorenko, ... The Journal of Organic Chemistry 76 (14), 5774-5781, 2011 | 51 | 2011 |
Photochemical in-flow synthesis of 2, 4-methanopyrrolidines: pyrrolidine analogues with improved water solubility and reduced lipophilicity VV Levterov, O Michurin, PO Borysko, S Zozulya, IV Sadkova, ... The Journal of Organic Chemistry 83 (23), 14350-14361, 2018 | 49 | 2018 |
Synthesis of trifluoromethyl-substituted 3-azabicyclo [n. 1.0] alkanes: advanced building blocks for drug discovery OS Artamonov, EY Slobodyanyuk, DM Volochnyuk, IV Komarov, ... Eur. J. Org. Chem 46, 3592-3598, 2014 | 49 | 2014 |