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Tung Le
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Year
Regulation of glucose metabolism–a perspective from cell bioprocessing
BC Mulukutla, A Yongky, T Le, DG Mashek, WS Hu
Trends in biotechnology 34 (8), 638-651, 2016
1442016
Single copy transgene integration in a transcriptionally active site for recombinant protein synthesis
SA O'Brien, K Lee, HY Fu, Z Lee, TS Le, CS Stach, MG McCann, ...
Biotechnology journal 13 (10), 1800226, 2018
392018
Advancing biopharmaceutical process science through transcriptome analysis
N Vishwanathan, H Le, T Le, WS Hu
Current opinion in biotechnology 30, 113-119, 2014
322014
Mechanism for multiplicity of steady states with distinct cell concentration in continuous culture of mammalian cells
A Yongky, J Lee, T Le, BC Mulukutla, P Daoutidis, WS Hu
Biotechnology and bioengineering 112 (7), 1437-1445, 2015
232015
Model-driven engineering of N-linked glycosylation in Chinese hamster ovary cells
CS Stach, MG McCann, CM O’Brien, TS Le, N Somia, X Chen, K Lee, ...
ACS synthetic biology 8 (11), 2524-2535, 2019
192019
Automated network generation and analysis of biochemical reaction pathways using RING
U Gupta, T Le, WS Hu, A Bhan, P Daoutidis
Metabolic engineering 49, 84-93, 2018
152018
An introduction to mammalian cell culture
TS Le, M McCann, SM Azarin, WS Hu
Chem Eng Prog 112 (4), 34-40, 2016
102016
An integrated platform for mucin‐type O‐glycosylation network generation and visualization
T Le, C O’Brien, U Gupta, G Sousa, P Daoutidis, WS Hu
Biotechnology and bioengineering 116 (6), 1341-1354, 2019
72019
Steering N-glycosylation of recombinant proteins using systems engineering
M McCann, T Le, C Stach, X Chen, N Somia, L Zhao, M Smanski, WS Hu
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018
2018
Systems Analysis in Mammalian Cell Biomanufacturing-Linking Energy Metabolism and Glycosylation
TS Le
University of Minnesota, 2018
2018
A synthetic biology based cell line engineering pipeline
WS Hu, CS Stach, S O’Brien, A Bandyopadhyay, M McCann, C O’Brien, ...
2018
Systems engineering N-glycans of recombinant therapeutic proteins
MG McCann, CS Stach, T Le, N Somia, M Smanski, WS Hu, X Chen, ...
2018
Systems engineering of N-glycans for the production of recombinant proteins in mammalian cells
T Le, C Stach, M McCann, S O'Brien, X Chen, L Zhao, M Smanski, WS Hu
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
On the shift-up to high lactate production in fed-batch culture of mammalian cells
T Le, C O'Brien, T Phan, E Liu, WS Hu
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Systems engineering of a CHO cell line for enhanced process robustness
K Lee, HY Fu, L Zhao, L Feng, T Le, H Pei, S Rajput, D Cho, N Somia, ...
2016
Unraveling the effect of energy metabolism on N-glycosylation of recombinant protein produced in mammalian cells
T Le, A Yongky, S Grimm, WS Hu
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015
2015
Bridging transcriptomics, modeling and process control in a systems approach for mammalian cell culture
V Konakovsky, T Le, A Yongky, R Raju, N Vishvanathan, C Herwig, ...
Proceedings, 142-147, 2015
2015
Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN, USA
A Yongky, J Lee, T Le, BC Mulukutla, P Daoutidis, WS Hu
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