| Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid β42 production by direct modulation of γ-secretase activity S Weggen, JL Eriksen, SA Sagi, CU Pietrzik, V Ozols, A Fauq, TE Golde, ... Journal of Biological Chemistry 278 (34), 31831-31837, 2003 | 387 | 2003 |
| Substrate-targeting γ-secretase modulators TL Kukar, TB Ladd, MA Bann, PC Fraering, R Narlawar, GM Maharvi, ... Nature 453 (7197), 925-929, 2008 | 377 | 2008 |
| Notch1 augments NF‐κB activity by facilitating its nuclear retention HM Shin, LM Minter, OH Cho, S Gottipati, AH Fauq, TE Golde, ... The EMBO journal 25 (1), 129-138, 2006 | 363 | 2006 |
| Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21 LM Minter, DM Turley, P Das, HM Shin, I Joshi, RG Lawlor, OH Cho, ... Nature immunology 6 (7), 680-688, 2005 | 356 | 2005 |
| Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production T Kukar, MP Murphy, JL Eriksen, SA Sagi, S Weggen, TE Smith, T Ladd, ... Nature medicine 11 (5), 545-550, 2005 | 351 | 2005 |
| Notch signaling is activated by TLR stimulation and regulates macrophage functions T Palaga, C Buranaruk, S Rengpipat, AH Fauq, TE Golde, SHE Kaufmann, ... European journal of immunology 38 (1), 174-183, 2008 | 274 | 2008 |
| Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells JB Samon, A Champhekar, LM Minter, JC Telfer, L Miele, A Fauq, P Das, ... Blood, The Journal of the American Society of Hematology 112 (5), 1813-1821, 2008 | 244 | 2008 |
| Phase III Double-Blind, Randomized, Placebo-Controlled Crossover Trial of Black Cohosh in the Management of Hot Flashes: NCCTG Trial N01CC1 BA Pockaj, JG Gallagher, CL Loprinzi, PJ Stella, DL Barton, JA Sloan, ... Journal of Clinical Oncology 24 (18), 2836-2841, 2006 | 243 | 2006 |
| Regulation of steady-state β-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme EA Eckman, SK Adams, FJ Troendle, BA Stodola, MA Kahn, AH Fauq, ... Journal of Biological Chemistry 281 (41), 30471-30478, 2006 | 239 | 2006 |
| Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases I Joshi, LM Minter, J Telfer, RM Demarest, AJ Capobianco, JC Aster, ... Blood, The Journal of the American Society of Hematology 113 (8), 1689-1698, 2009 | 236 | 2009 |
| Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice NF Fitz, A Cronican, T Pham, A Fogg, AH Fauq, R Chapman, I Lefterov, ... Journal of Neuroscience 30 (20), 6862-6872, 2010 | 199 | 2010 |
| Notch regulates cytolytic effector function in CD8+ T cells OH Cho, HM Shin, L Miele, TE Golde, A Fauq, LM Minter, BA Osborne The Journal of Immunology 182 (6), 3380-3389, 2009 | 178 | 2009 |
| Peptide nucleic acids targeted to the neurotensin receptor and administered ip cross the blood–brain barrier and specifically reduce gene expression BM Tyler, K Jansen, DJ McCormick, CL Douglas, M Boules, JA Stewart, ... Proceedings of the National Academy of Sciences 96 (12), 7053-7058, 1999 | 168 | 1999 |
| Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis*♦ CA Patwardhan, A Fauq, LB Peterson, C Miller, BSJ Blagg, A Chadli Journal of Biological Chemistry 288 (10), 7313-7325, 2013 | 160 | 2013 |
| Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice NF Fitz, AA Cronican, M Saleem, AH Fauq, R Chapman, I Lefterov, ... Journal of Neuroscience 32 (38), 13125-13136, 2012 | 149 | 2012 |
| Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin MA Leissring, E Malito, S Hedouin, L Reinstatler, T Sahara, SO Abdul-Hay, ... PloS one 5 (5), e10504, 2010 | 132 | 2010 |
| Cell‐free assays for γ‐secretase activity C McLendon, TP Xin, C Ziani-Cherif, MP Murphy, KA Findlay, PA Lewis, ... The FASEB Journal 14 (15), 2383-2386, 2000 | 131 | 2000 |
| Pharmacokinetics and tissue distribution of a peptide nucleic acid after intravenous administration BM McMahon, D Mays, J Lipsky, JA Stewart, A Fauq, E Richelson Antisense and Nucleic Acid Drug Development 12 (2), 65-70, 2002 | 130 | 2002 |
| Presenilin 1 regulates pharmacologically distinct γ-secretase activities: implications for the role of presenilin in γ-secretase cleavage MP Murphy, SN Uljon, PE Fraser, A Fauq, HA Lookingbill, KA Findlay, ... Journal of Biological Chemistry 275 (34), 26277-26284, 2000 | 125 | 2000 |
| Cisplatin and dimethyl sulfoxide react to form an adducted compound with reduced cytotoxicity and neurotoxicity SJ Fischer, LM Benson, A Fauq, S Naylor, AJ Windebank Neurotoxicology 29 (3), 444-452, 2008 | 112 | 2008 |
