| The IL-4 receptor: signaling mechanisms and biologic functions K Nelms, AD Keegan, J Zamorano, JJ Ryan, WE Paul Annual review of immunology 17 (1), 701-738, 1999 | 1988 | 1999 |
| Interleukin-2 receptor γ chain: a functional component of the interleukin-4 receptor SM Russell, AD Keegan, N Harada, Y Nakamura, M Noguchi, P Leland, ... Science 262 (5141), 1880-1883, 1993 | 1045 | 1993 |
| Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system SL LaPorte, ZS Juo, J Vaclavikova, LA Colf, X Qi, NM Heller, AD Keegan, ... Cell 132 (2), 259-272, 2008 | 579 | 2008 |
| Interleukin-4 and interleukin-13 signaling connections maps AE Kelly-Welch, EM Hanson, MR Boothby, AD Keegan Science 300 (5625), 1527-1528, 2003 | 555 | 2003 |
| Regulation of inflammation by interleukin-4: a review of “alternatives” IG Luzina, AD Keegan, NM Heller, GAW Rook, T Shea-Donohue, ... Journal of leukocyte biology 92 (4), 753-764, 2012 | 453 | 2012 |
| Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis FW Quelle, K Shimoda, W Thierfelder, C Fischer, A Kim, SM Ruben, ... Molecular and cellular biology, 1995 | 442 | 1995 |
| An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth AD Keegan, K Nelms, M White, LM Wang, JH Pierce, WE Paul Cell 76 (5), 811-820, 1994 | 387 | 1994 |
| Multichain immune recognition receptors: similarities in structure and signaling pathways AD Keegan, WE Paul Immunology today 13 (2), 63-68, 1992 | 255 | 1992 |
| Control of RSV-induced lung injury by alternatively activated macrophages is IL-4Rα-, TLR4-, and IFN-β-dependent KA Shirey, LM Pletneva, AC Puche, AD Keegan, GA Prince, JCG Blanco, ... Mucosal immunology 3 (3), 291-300, 2010 | 243 | 2010 |
| Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor JJ Ryan, LJ McReynolds, A Keegan, LH Wang, E Garfein, P Rothman, ... Immunity 4 (2), 123-132, 1996 | 227 | 1996 |
| Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells. LM Wang, AD Keegan, W Li, GE Lienhard, S Pacini, JS Gutkind, ... Proceedings of the National Academy of Sciences 90 (9), 4032-4036, 1993 | 226 | 1993 |
| IL‐4 activates a distinct signal transduction cascade from IL‐3 in factor‐dependent myeloid cells. LM Wang, AD Keegan, WE Paul, MA Heidaran, JS Gutkind, JH Pierce The EMBO Journal 11 (13), 4899-4908, 1992 | 211 | 1992 |
| IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway. J Zamorano, HY Wang, LM Wang, JH Pierce, AD Keegan Journal of immunology (Baltimore, Md.: 1950) 157 (11), 4926-4934, 1996 | 183 | 1996 |
| Regulation of the T helper cell type 2 (Th2)/T regulatory cell (Treg) balance by IL-4 and STAT6 S Chapoval, P Dasgupta, NJ Dorsey, AD Keegan Journal of leukocyte biology 87 (6), 1011-1018, 2010 | 182 | 2010 |
| Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages NM Heller, X Qi, IS Junttila, KA Shirey, SN Vogel, WE Paul, AD Keegan Science signaling 1 (51), ra17-ra17, 2008 | 181 | 2008 |
| IL-4 promotes the formation of multinucleated giant cells from macrophage precursors by a STAT6-dependent, homotypic mechanism: contribution of E-cadherin JL Moreno, I Mikhailenko, MM Tondravi, AD Keegan Journal of Leucocyte Biology 82 (6), 1542-1553, 2007 | 179 | 2007 |
| IL-4 suppresses osteoclast development and mature osteoclast function by a STAT6-dependent mechanism: irreversible inhibition of the differentiation program activated by RANKL JL Moreno, M Kaczmarek, AD Keegan, M Tondravi Blood 102 (3), 1078-1086, 2003 | 172 | 2003 |
| Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism KA Shirey, LE Cole, AD Keegan, SN Vogel The Journal of Immunology 181 (6), 4159-4167, 2008 | 167 | 2008 |
| Interleukin 4 receptor: signaling mechanisms AD Keegan, K Nelms, LM Wang, JH Pierce, WE Paul Immunology Today 15 (9), 423-432, 1994 | 164 | 1994 |
| Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention WM Gwinn, JM Damsker, R Falahati, I Okwumabua, A Kelly-Welch, ... The Journal of Immunology 177 (7), 4870-4879, 2006 | 162 | 2006 |
