Einar M. Sigurdsson
Einar M. Sigurdsson
Professor of Neuroscience and Physiology and Psychiatry
Підтверджена електронна адреса в nyumc.org
Назва
Посилання
Посилання
Рік
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ...
Autophagy 8 (4), 445-544, 2012
7750*2012
β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy
C Soto, EM Sigurdsson, L Morelli, RA Kumar, EM Castano, B Frangione
Nature medicine 4 (7), 822-826, 1998
10151998
Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements
AA Asuni, A Boutajangout, D Quartermain, EM Sigurdsson
Journal of Neuroscience 27 (34), 9115-9129, 2007
5132007
Tau-targeting therapies for Alzheimer disease
EE Congdon, EM Sigurdsson
Nature Reviews Neurology 14 (7), 399-415, 2018
3922018
Immunization with a nontoxic/nonfibrillar amyloid-β homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice
EM Sigurdsson, H Scholtzova, PD Mehta, B Frangione, T Wisniewski
The American journal of pathology 159 (2), 439-447, 2001
3352001
Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging
YZ Wadghiri, EM Sigurdsson, M Sadowski, JI Elliott, Y Li, H Scholtzova, ...
Magnetic Resonance in Medicine: An Official Journal of the International …, 2003
3092003
Passive immunization targeting pathological phospho‐tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
A Boutajangout, J Ingadottir, P Davies, EM Sigurdsson
Journal of neurochemistry 118 (4), 658-667, 2011
3082011
Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model
A Boutajangout, D Quartermain, EM Sigurdsson
Journal of Neuroscience 30 (49), 16559-16566, 2010
2892010
Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging
JF Poduslo, TM Wengenack, GL Curran, T Wisniewski, EM Sigurdsson, ...
Neurobiology of disease 11 (2), 315-329, 2002
2572002
Copper chelation delays the onset of prion disease
EM Sigurdsson, DR Brown, MA Alim, H Scholtzova, R Carp, HC Meeker, ...
Journal of Biological Chemistry 278 (47), 46199-46202, 2003
2242003
Immunization delays the onset of prion disease in mice
EM Sigurdsson, DR Brown, M Daniels, RJ Kascsak, R Kascsak, R Carp, ...
The American journal of pathology 161 (1), 13-17, 2002
2212002
Tau immunotherapy for Alzheimer's disease
JT Pedersen, EM Sigurdsson
Trends in molecular medicine 21 (6), 394-402, 2015
2182015
An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-β derivatives
EM Sigurdsson, E Knudsen, A Asuni, C Fitzer-Attas, D Sage, ...
Journal of Neuroscience 24 (28), 6277-6282, 2004
1752004
An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-β derivatives
EM Sigurdsson, E Knudsen, A Asuni, C Fitzer-Attas, D Sage, ...
Journal of Neuroscience 24 (28), 6277-6282, 2004
1752004
Extracellular tau oligomers produce an immediate impairment of LTP and memory
M Fá, D Puzzo, R Piacentini, A Staniszewski, H Zhang, MA Baltrons, ...
Scientific reports 6 (1), 1-15, 2016
1712016
Antibody uptake into neurons occurs primarily via clathrin-dependent Fcγ receptor endocytosis and is a prerequisite for acute tau protein clearance
EE Congdon, J Gu, HBR Sait, EM Sigurdsson
Journal of Biological Chemistry 288 (49), 35452-35465, 2013
1572013
A synthetic peptide blocking the apolipoprotein E/β-amyloid binding mitigates β-amyloid toxicity and fibril formation in vitro and reduces β-amyloid plaques in transgenic mice
M Sadowski, J Pankiewicz, H Scholtzova, JA Ripellino, Y Li, SD Schmidt, ...
The American journal of pathology 165 (3), 937-948, 2004
1522004
Immunotherapy targeting pathological tau protein in Alzheimer's disease and related tauopathies
EM Sigurdsson
journal of Alzheimer's Disease 15 (2), 157-168, 2008
1482008
Two novel Tau antibodies targeting the 396/404 region are primarily taken up by neurons and reduce Tau protein pathology
J Gu, EE Congdon, EM Sigurdsson
Journal of Biological Chemistry 288 (46), 33081-33095, 2013
1442013
Memantine leads to behavioral improvement and amyloid reduction in Alzheimer's‐disease‐model transgenic mice shown as by micromagnetic resonance imaging
H Scholtzova, YZ Wadghiri, M Douadi, EM Sigurdsson, YS Li, ...
Journal of neuroscience research 86 (12), 2784-2791, 2008
1412008
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