|Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention|
NM Davis, M Sokolosky, K Stadelman, SL Abrams, M Libra, S Candido, ...
Oncotarget 5 (13), 4603, 2014
|Negative regulation of PI 3‐kinase by Ruk, a novel adaptor protein|
I Gout, G Middleton, J Adu, NN Ninkina, LB Drobot, V Filonenko, ...
The EMBO Journal 19 (15), 4015-4025, 2000
|Involvement of Akt and mTOR in chemotherapeutic-and hormonal-based drug resistance and response to radiation in breast cancer cells|
LS Steelman, P Navolanic, WH Chappell, SL Abrams, EWT Wong, ...
Cell Cycle 10 (17), 3003-3015, 2011
|Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy|
ML Sokolosky, KM Stadelman, WH Chappell, SL Abrams, AM Martelli, ...
Oncotarget 2 (7), 538, 2011
|CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes|
I Tossidou, B Teng, L Drobot, C Meyer-Schwesinger, K Worthmann, ...
Journal of Biological Chemistry 285 (33), 25285-25295, 2010
|Differential effects of P2Y1 and P2Y12 nucleotide receptors on ERK1/ERK2 and phosphatidylinositol 3‐kinase signalling and cell proliferation in serum‐deprived …|
R Czajkowski, W Banachewicz, O Ilnytska, LB Drobot, J Barańska
British journal of pharmacology 141 (3), 497-507, 2004
|Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS|
S Havrylov, Y Rzhepetskyy, A Malinowska, L Drobot, MJ Redowicz
Proteome science 7 (1), 21, 2009
|Intersectin 1 forms a complex with adaptor protein Ruk/CIN85 in vivo independently of epidermal growth factor stimulation|
O Nikolaienko, I Skrypkina, L Tsyba, Y Fedyshyn, D Morderer, V Buchman, ...
Cellular signalling 21 (5), 753-759, 2009
|Advances in targeting signal transduction pathways|
JA McCubrey, LS Steelman, WH Chappell, L Sun, NM Davis, SL Abrams, ...
Oncotarget 3 (12), 1505, 2012
|Ruk is ubiquitinated but not degraded by the proteasome|
F Verdier, T Valovka, A Zhyvoloup, LB Drobot, V Buchman, M Waterfield, ...
European journal of biochemistry 269 (14), 3402-3408, 2002
|Multiple domains of Ruk/CIN85/SETA/CD2BP3 are involved in interaction with p85α regulatory subunit of PI 3-kinase|
EB Borthwick, IV Korobko, C Luke, VR Drel, YY Fedyshyn, N Ninkina, ...
Journal of molecular biology 343 (4), 1135-1146, 2004
|Increased levels of the HER1 adaptor protein Ruk l /CIN85 contribute to breast cancer malignancy|
A Samoylenko, B Vynnytska-Myronovska, N Byts, N Kozlova, O Basaraba, ...
Carcinogenesis 33 (10), 1976-1984, 2012
|Expression of adaptor protein Ruk/CIN85 isoforms in cell lines of various tissue origins and human melanoma|
O Mayevska, H Shuvayeva, N Igumentseva, S Havrylov, O Basaraba, ...
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|Determining the structure of peptides combined method Dansyl-Edman. Molecular methods. biology. Kiev|
NM Gusak, MN Ovander, LB Drobot, SB Serebryanyy
Naukova Dumka, 1979
|Fullerene C60 Penetration into Leukemic Cells and Its Photoinduced Cytotoxic Effects|
D Franskevych, K Palyvoda, D Petukhov, S Prylutska, I Grynyuk, ...
Nanoscale research letters 12 (1), 40, 2017
|Radiation-induced DNA damage and its repair in lymphocytes of patients with head and neck cancer and healthy donors.|
O Palyvoda, I Mukalov, J Polanska, A Wygoda, L Drobot, M Widel, ...
Anticancer research 22 (3), 1721-1725, 2002
|Positive selection of mutants defective in transcriptional repression of riboflavin synthesis by iron in the flavinogenic yeast Pichia guilliermondii|
YR Boretsky, KY Kapustyak, LR Fayura, OV Stasyk, MM Stenchuk, ...
FEMS yeast research 5 (9), 829-837, 2005
|Identification and characterization of a novel mammalian isoform of the endocytic adaptor ITSN1|
M Dergai, I Skrypkina, O Dergai, L Tsyba, O Novokhatska, V Filonenko, ...
Gene 485 (2), 120-129, 2011
|Critical roles of EGFR family members in breast cancer and breast cancer stem cells: targets for therapy|
L S Steelman, T Fitzgerald, K Lertpiriyapong, L Cocco, M Y Follo, ...
Current pharmaceutical design 22 (16), 2358-2388, 2016
|Functional and regulatory properties of p70S6 kinase β|
TI Valovka, VV Filonenko, SS Palchevsky, MM Velikiy, LB Drobot, ...
Biopolymers and Cell 15 (5), 415-421, 1999