| Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention NM Davis, M Sokolosky, K Stadelman, SL Abrams, M Libra, S Candido, ... Oncotarget 5 (13), 4603, 2014 | 315 | 2014 |
| Negative regulation of PI 3‐kinase by Ruk, a novel adaptor protein I Gout, G Middleton, J Adu, NN Ninkina, LB Drobot, V Filonenko, ... The EMBO journal, 2000 | 177 | 2000 |
| Involvement of Akt and mTOR in chemotherapeutic-and hormonal-based drug resistance and response to radiation in breast cancer cells LS Steelman, P Navolanic, WH Chappell, SL Abrams, EWT Wong, ... Cell Cycle 10 (17), 3003-3015, 2011 | 93 | 2011 |
| Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy ML Sokolosky, KM Stadelman, WH Chappell, SL Abrams, AM Martelli, ... Oncotarget 2 (7), 538, 2011 | 92 | 2011 |
| CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes I Tossidou, B Teng, L Drobot, C Meyer-Schwesinger, K Worthmann, ... Journal of biological chemistry 285 (33), 25285-25295, 2010 | 78 | 2010 |
| Fullerene C60 Penetration into Leukemic Cells and Its Photoinduced Cytotoxic Effects D Franskevych, K Palyvoda, D Petukhov, S Prylutska, I Grynyuk, ... Nanoscale Research Letters 12, 1-9, 2017 | 67 | 2017 |
| Differential effects of P2Y1 and P2Y12 nucleotide receptors on ERK1/ERK2 and phosphatidylinositol 3‐kinase signalling and cell proliferation in serum‐deprived … R Czajkowski, W Banachewicz, O Ilnytska, LB Drobot, J Barańska British journal of pharmacology 141 (3), 497-507, 2004 | 61 | 2004 |
| Advances in targeting signal transduction pathways JA McCubrey, LS Steelman, WH Chappell, L Sun, NM Davis, SL Abrams, ... Oncotarget 3 (12), 1505, 2012 | 59 | 2012 |
| Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS S Havrylov, Y Rzhepetskyy, A Malinowska, L Drobot, MJ Redowicz Proteome science 7, 1-19, 2009 | 59 | 2009 |
| Increased levels of the HER1 adaptor protein Ruk l /CIN85 contribute to breast cancer malignancy A Samoylenko, B Vynnytska-Myronovska, N Byts, N Kozlova, O Basaraba, ... Carcinogenesis 33 (10), 1976-1984, 2012 | 46 | 2012 |
| Intersectin 1 forms a complex with adaptor protein Ruk/CIN85 in vivo independently of epidermal growth factor stimulation O Nikolaienko, I Skrypkina, L Tsyba, Y Fedyshyn, D Morderer, V Buchman, ... Cellular signalling 21 (5), 753-759, 2009 | 45 | 2009 |
| Critical roles of EGFR family members in breast cancer and breast cancer stem cells: targets for therapy L S Steelman, T Fitzgerald, K Lertpiriyapong, L Cocco, M Y Follo, ... Current Pharmaceutical Design 22 (16), 2358-2388, 2016 | 44 | 2016 |
| Ruk is ubiquitinated but not degraded by the proteasome F Verdier, T Valovka, A Zhyvoloup, LB Drobot, V Buchman, M Waterfield, ... European journal of biochemistry 269 (14), 3402-3408, 2002 | 40 | 2002 |
| Expression of adaptor protein Ruk/CIN85 isoforms in cell lines of various tissue origins and human melanoma O Mayevska, H Shuvayeva, N Igumentseva, S Havrylov, O Basaraba, ... Інститут експериментальної патології, онкології і радіобіології ім. РЄ …, 2006 | 37 | 2006 |
| Multiple domains of Ruk/CIN85/SETA/CD2BP3 are involved in interaction with p85α regulatory subunit of PI 3-kinase EB Borthwick, IV Korobko, C Luke, VR Drel, YY Fedyshyn, N Ninkina, ... Journal of molecular biology 343 (4), 1135-1146, 2004 | 35 | 2004 |
| Rendimento de óleo essencial de Salvia officinalis L. sob ação de reguladores vegetais JA Povh, EO Ono Acta Scientiarum. Biological Sciences 28 (3), 189-193, 2006 | 34 | 2006 |
| Toxicity of C60 fullerene–cisplatin nanocomplex against Lewis lung carcinoma cells S Prylutska, I Grynyuk, T Skaterna, I Horak, A Grebinyk, L Drobot, ... Archives of Toxicology 93, 1213-1226, 2019 | 29 | 2019 |
| Radiation-induced DNA damage and its repair in lymphocytes of patients with head and neck cancer and healthy donors. O Palyvoda, I Mukalov, J Polanska, A Wygoda, L Drobot, M Widel, ... Anticancer research 22 (3), 1721-1725, 2002 | 29 | 2002 |
| Positive selection of mutants defective in transcriptional repression of riboflavin synthesis by iron in the flavinogenic yeast Pichia guilliermondii YR Boretsky, KY Kapustyak, LR Fayura, OV Stasyk, MM Stenchuk, ... FEMS yeast research 5 (9), 829-837, 2005 | 28 | 2005 |
| Berberine alkaloids inhibit the proliferation and metastasis of breast carcinoma cells involving Wnt/β-catenin signaling and EMT L Dian, Z Xu, Y Sun, J Li, H Lu, M Zheng, J Wang, L Drobot, I Horak Phytochemistry 200, 113217, 2022 | 19 | 2022 |
