| Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching by single-molecule calorimetry X Zhang, H Chen, S Le, I Rouzina, PS Doyle, J Yan Proceedings of the National Academy of Sciences 110 (10), 3865-3870, 2013 | 163 | 2013 |
| Tension-dependent stretching activates ZO-1 to control the junctional localization of its interactors D Spadaro, S Le, T Laroche, I Mean, L Jond, J Yan, S Citi Current biology 27 (24), 3783-3795. e8, 2017 | 136 | 2017 |
| mDia1 senses both force and torque during F-actin filament polymerization M Yu, X Yuan, C Lu, S Le, R Kawamura, AK Efremov, Z Zhao, MM Kozlov, ... Nature communications 8 (1), 1650, 2017 | 96 | 2017 |
| Mechanotransmission and mechanosensing of human alpha-actinin 1 S Le, X Hu, M Yao, H Chen, M Yu, X Xu, N Nakazawa, FM Margadant, ... Cell reports 21 (10), 2714-2723, 2017 | 84 | 2017 |
| Elasticity of the transition state leading to an unexpected mechanical stabilization of titin immunoglobulin domains G Yuan, S Le, M Yao, H Qian, X Zhou, J Yan, H Chen Angewandte Chemie 129 (20), 5582-5585, 2017 | 77 | 2017 |
| Dystrophin as a molecular shock absorber S Le, M Yu, L Hovan, Z Zhao, J Ervasti, J Yan ACS nano 12 (12), 12140-12148, 2018 | 68 | 2018 |
| Uncovering mechanosensing mechanisms at the single protein level using magnetic tweezers S Le, R Liu, CT Lim, J Yan Methods 94, 13-18, 2016 | 53 | 2016 |
| Mechanochemical regulations of RPA's binding to ssDNA J Chen, S Le, A Basu, WJ Chazin, J Yan Scientific reports 5 (1), 9296, 2015 | 51 | 2015 |
| Force and ATP hydrolysis dependent regulation of RecA nucleoprotein filament by single-stranded DNA binding protein H Fu, S Le, H Chen, K Muniyappa, J Yan Nucleic acids research 41 (2), 924-932, 2013 | 49 | 2013 |
| Structural–elastic determination of the force-dependent transition rate of biomolecules S Guo, Q Tang, M Yao, H You, S Le, H Chen, J Yan Chemical science 9 (27), 5871-5882, 2018 | 45 | 2018 |
| Direct single-molecule quantification reveals unexpectedly high mechanical stability of vinculin—talin/α-catenin linkages S Le, M Yu, J Yan Science advances 5 (12), eaav2720, 2019 | 40 | 2019 |
| Force-dependent regulation of talin–KANK1 complex at focal adhesions M Yu, S Le, YC Ammon, BT Goult, A Akhmanova, J Yan Nano letters 19 (9), 5982-5990, 2019 | 40 | 2019 |
| Effects of mechanical stimuli on profilin-and formin-mediated actin polymerization M Yu, S Le, AK Efremov, X Zeng, A Bershadsky, J Yan Nano Letters 18 (8), 5239-5247, 2018 | 40 | 2018 |
| Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1 RE Gough, MC Jones, T Zacharchenko, S Le, M Yu, G Jacquemet, ... Journal of Biological Chemistry 297 (1), 2021 | 36 | 2021 |
| Disturbance-free rapid solution exchange for magnetic tweezers single-molecule studies S Le, M Yao, J Chen, AK Efremov, S Azimi, J Yan Nucleic acids research 43 (17), e113-e113, 2015 | 32 | 2015 |
| Bacillus subtilis RecA with DprA–SsbA antagonizes RecX function during natural transformation S Le, E Serrano, R Kawamura, B Carrasco, J Yan, JC Alonso Nucleic acids research 45 (15), 8873-8885, 2017 | 31 | 2017 |
| Mechanosensing of DNA bending in a single specific protein-DNA complex S Le, H Chen, P Cong, J Lin, P Dröge, J Yan Scientific reports 3 (1), 3508, 2013 | 29 | 2013 |
| Mechanical stability of αT-catenin and its activation by force for vinculin binding SM Pang, S Le, AV Kwiatkowski, J Yan Molecular biology of the cell 30 (16), 1930-1937, 2019 | 28 | 2019 |
| Phosphorylation Reduces the Mechanical Stability of α‐Catenin/β‐Catenin Complex S Le, M Yu, J Yan Angewandte Chemie, 2019 | 23 | 2019 |
| Label-free single-molecule quantification of rapamycin-induced FKBP–FRB dimerization for direct control of cellular mechanotransduction Y Wang, SFH Barnett, S Le, Z Guo, X Zhong, P Kanchanawong, J Yan Nano letters 19 (10), 7514-7525, 2019 | 23 | 2019 |
Jie YanProfessor, Department of Physics and Mechanobiology Institute, National University ofVerified email at nus.edu.sg
