Підписатись
Kostiantyn Dreval
Kostiantyn Dreval
Canada’s Michael Smith Genome Sciences Centre
Підтверджена електронна адреса в bcgsc.ca - Домашня сторінка
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Посилання
Рік
Super-enhancer hypermutation alters oncogene expression in B cell lymphoma
E Bal, R Kumar, M Hadigol, AB Holmes, LK Hilton, JW Loh, K Dreval, ...
Nature 607 (7920), 808-815, 2022
732022
MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis
A de Conti, JF Ortega, V Tryndyak, K Dreval, FS Moreno, I Rusyn, ...
Oncotarget 8 (51), 88517, 2017
602017
Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans
D Yu, L Wu, P Gill, WH Tolleson, S Chen, J Sun, B Knox, Y Jin, W Xiao, ...
Archives of toxicology 92, 845-858, 2018
542018
Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma
N Thomas, K Dreval, DS Gerhard, LK Hilton, JS Abramson, RF Ambinder, ...
Blood 141 (8), 904-916, 2023
482023
Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay
JE Seo, V Tryndyak, Q Wu, K Dreval, I Pogribny, M Bryant, T Zhou, ...
Archives of toxicology 93, 1433-1448, 2019
412019
Inhibition of the cell death pathway in nonalcoholic steatohepatitis (NASH)-related hepatocarcinogenesis is associated with histone H4 lysine 16 deacetylation
A de Conti, K Dreval, V Tryndyak, OE Orisakwe, SA Ross, FA Beland, ...
Molecular Cancer Research 15 (9), 1163-1172, 2017
382017
Effect of aflatoxin B1, benzo [a] pyrene, and methapyrilene on transcriptomic and epigenetic alterations in human liver HepaRG cells
V Tryndyak, I Kindrat, K Dreval, MI Churchwell, FA Beland, IP Pogribny
Food and chemical toxicology 121, 214-223, 2018
332018
Gene expression and DNA methylation alterations during non-alcoholic steatohepatitis-associated liver carcinogenesis
K Dreval, V Tryndyak, A De Conti, FA Beland, IP Pogribny
Frontiers in genetics 10, 486, 2019
282019
Epigenetically mediated inhibition of S-adenosylhomocysteine hydrolase and the associated dysregulation of 1-carbon metabolism in nonalcoholic steatohepatitis and …
IP Pogribny, K Dreval, I Kindrat, S Melnyk, L Jimenez, A de Conti, ...
The FASEB Journal 32 (3), 1591, 2018
262018
Cellular and molecular effects of prolonged low-level sodium arsenite exposure on human hepatic HepaRG cells
K Dreval, V Tryndyak, I Kindrat, NC Twaddle, OE Orisakwe, TK Mudalige, ...
Toxicological sciences 162 (2), 676-687, 2018
202018
Mir-1247 blocks sox9–mediated regeneration in alcohol-and fibrosis-associated acute kidney injury in mice
K Dreval, A de Conti, S Furuya, FA Beland, I Rusyn, IP Pogribny
Toxicology 384, 40-49, 2017
182017
Нові продуценти целюлозолітичних ензимів серед вищих базидіальних грибів
КГ Древаль, МІ Бойко
Biotechnology, 87-92, 2011
182011
Histopathological and molecular signatures of a mouse model of acute-on-chronic alcoholic liver injury demonstrate concordance with human alcoholic hepatitis
S Furuya, JA Cichocki, K Konganti, K Dreval, T Uehara, Y Katou, ...
Toxicological Sciences 170 (2), 427-437, 2019
172019
Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns
K Dreval, LK Hilton, M Cruz, H Shaalan, S Ben-Neriah, M Boyle, ...
Blood 142 (6), 561-573, 2023
152023
HDAC1 negatively regulates selective mitotic chromatin binding of the Notch effector RBPJ in a KDM5A-dependent manner
K Dreval, RJ Lake, HY Fan
Nucleic acids research 47 (9), 4521-4538, 2019
152019
Poly (ADP-ribose) polymerase 1 (PARP1) promotes oxidative stress–induced association of Cockayne syndrome group B protein with chromatin
EL Boetefuer, RJ Lake, K Dreval, HY Fan
Journal of Biological Chemistry 293 (46), 17863-17874, 2018
142018
Editor’s highlight: organ-specific epigenetic changes induced by the nongenotoxic liver carcinogen methapyrilene in fischer 344 rats
S Shpyleva, K Dreval, A de Conti, I Kindrat, S Melnyk, J Yan, T Chen, ...
Toxicological Sciences 156 (1), 190-198, 2017
102017
Relapse timing is associated with distinct evolutionary dynamics in diffuse large B-cell lymphoma
LK Hilton, HS Ngu, B Collinge, K Dreval, S Ben-Neriah, CK Rushton, ...
Journal of Clinical Oncology 41 (25), 4164-4177, 2023
72023
Shared and distinct genetic features in human and canine B-cell lymphomas
KM Coyle, T Hillman, M Cheung, BM Grande, KR Bushell, SE Arthur, ...
Blood Advances 6 (11), 3404-3409, 2022
72022
Effect of methapyrilene hydrochloride on hepatic intracellular iron metabolism in vivo and in vitro
I Kindrat, K Dreval, S Shpyleva, V Tryndyak, A de Conti, TK Mudalige, ...
Toxicology Letters 281, 65-73, 2017
72017
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