Підписатись
David R. Brown
David R. Brown
Підтверджена електронна адреса в bath.ac.uk - Домашня сторінка
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Посилання
Рік
The cellular prion protein binds copper in vivo
DR Brown, K Qin, JW Herms, A Madlung, J Manson, R Strome, PE Fraser, ...
Nature 390 (6661), 684, 1997
16731997
Normal prion protein has an activity like that of superoxide dismutase
DR Brown, W Boon-Seng, F Hafiz, C Clive, SJ HASWELL, IM JONES
Biochemical Journal 344 (1), 1-5, 1999
7261999
Role of microglia and host prion protein in neurotoxicity of a prion protein fragment
DR Brown, B Schmidt, HA Kretzschmar
Nature 380 (6572), 345, 1996
6371996
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity
DR Brown, WJ Schulz-Schaeffer, B Schmidt, HA Kretzschmar
Experimental neurology 146 (1), 104-112, 1997
6081997
Prion protein expression and superoxide dismutase activity
DR BROWN, A Besinger
Biochemical Journal 334 (2), 423-429, 1998
3701998
Consequences of manganese replacement of copper for prion protein function and proteinase resistance
DR Brown, F Hafiz, LL Glasssmith, BS Wong, IM Jones, C Clive, ...
The EMBO journal 19 (6), 1180-1186, 2000
3312000
Antioxidant activity related to copper binding of native prion protein
DR Brown, C Clive, SJ Haswell
Journal of neurochemistry 76 (1), 69-76, 2001
3032001
Role of microglia in neuronal cell death in prion disease
A Giese, DR Brown, MH Groschup, C Feldmann, I Haist, HA Kretzschmar
Brain Pathology 8 (3), 449-457, 1998
2981998
Lack of prion protein expression results in a neuronal phenotype sensitive to stress
DR Brown, RSJ Nicholas, L Canevari
Journal of neuroscience research 67 (2), 211-224, 2002
2932002
Preferential Cu2+ coordination by His96 and His111 induces β-sheet formation in the unstructured amyloidogenic region of the prion protein
CE Jones, SR Abdelraheim, DR Brown, JH Viles
Journal of Biological Chemistry 279 (31), 32018-32027, 2004
2902004
Prion and prejudice: normal protein and the synapse
DR Brown
Trends in neurosciences 24 (2), 85-90, 2001
2782001
Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases
DR Brown, H Kozlowski
Dalton Transactions, 1907-1917, 2004
2732004
Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment.
DR Brown, J Herms, HA Kretzschmar
Neuroreport 5 (16), 2057-2060, 1994
2601994
Immunization delays the onset of prion disease in mice
EM Sigurdsson, DR Brown, M Daniels, RJ Kascsak, R Kascsak, R Carp, ...
The American journal of pathology 161 (1), 13-17, 2002
2472002
Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein
BS Wong, T Liu, R Li, T Pan, RB Petersen, MA Smith, P Gambetti, G Perry, ...
Journal of neurochemistry 76 (2), 565-572, 2001
2442001
Copper chelation delays the onset of prion disease
EM Sigurdsson, DR Brown, MA Alim, H Scholtzova, R Carp, HC Meeker, ...
Journal of Biological Chemistry 278 (47), 46199-46202, 2003
2422003
Aberrant metal binding by prion protein in human prion disease
BS Wong, SG Chen, M Colucci, Z Xie, T Pan, T Liu, R Li, P Gambetti, ...
Journal of neurochemistry 78 (6), 1400-1408, 2001
2402001
Seeking a mechanism for the toxicity of oligomeric α-synuclein
H Roberts, D Brown
Biomolecules 5 (2), 282-305, 2015
2382015
Metal imbalance and compromised antioxidant function are early changes in prion disease
AM Thackray, R Knight, SJ Haswell, R Bujdoso, DR Brown
Biochemical Journal 362 (2), 253-258, 2002
2372002
Alpha-synuclein is a cellular ferrireductase
P Davies, D Moualla, DR Brown
PloS one 6 (1), e15814, 2011
2252011
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Статті 1–20