Підписатись
Brian M. Wasko
Brian M. Wasko
Assistant Professor, Western University of Health Sciences, Oregon
Підтверджена електронна адреса в westernu.edu - Домашня сторінка
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Рік
mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome
SC Johnson, ME Yanos, EB Kayser, A Quintana, M Sangesland, ...
Science 342 (6165), 1524-1528, 2013
5152013
A comprehensive analysis of replicative lifespan in 4,698 single-gene deletion strains uncovers conserved mechanisms of aging
MA McCormick, JR Delaney, M Tsuchiya, S Tsuchiyama, A Shemorry, ...
Cell metabolism 22 (5), 895-906, 2015
2512015
H3K36 methylation promotes longevity by enhancing transcriptional fidelity
P Sen, W Dang, G Donahue, J Dai, J Dorsey, X Cao, W Liu, K Cao, ...
Genes & development 29 (13), 1362-1376, 2015
2262015
Molecular mechanisms underlying genotype‐dependent responses to dietary restriction
J Schleit, SC Johnson, CF Bennett, M Simko, N Trongtham, A Castanza, ...
Aging cell 12 (6), 1050-1061, 2013
1702013
pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast
C Murakami, JR Delaney, A Chou, D Carr, J Schleit, GL Sutphin, EH An, ...
Cell cycle 11 (16), 3087-3096, 2012
802012
Yeast replicative aging: a paradigm for defining conserved longevity interventions
BM Wasko, M Kaeberlein
FEMS yeast research 14 (1), 148-159, 2014
782014
Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate
BM Wasko, A Dudakovic, RJ Hohl
Journal of Pharmacology and Experimental Therapeutics 337 (2), 540-546, 2011
712011
Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae
JR Delaney, C Murakami, A Chou, D Carr, J Schleit, GL Sutphin, EH An, ...
Experimental gerontology 48 (10), 1006-1013, 2013
642013
Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylation
AJ Wiemer, SY Jose, LW Shull, RJ Barney, BM Wasko, KM Lamb, RJ Hohl, ...
Bioorganic & medicinal chemistry 16 (7), 3652-3660, 2008
622008
Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans
CF Bennett, JJ Kwon, C Chen, J Russell, K Acosta, N Burnaevskiy, ...
PLoS genetics 13 (3), e1006695, 2017
492017
Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae
BM Wasko, CL Holland, MA Resnick, LK Lewis
DNA repair 8 (2), 162-169, 2009
452009
Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast
C Beaupere, L Dinatto, BM Wasko, RB Chen, L VanValkenburg, ...
Proceedings of the National Academy of Sciences 115 (38), 9586-9591, 2018
432018
A novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitro [S]
BM Wasko, JP Smits, LW Shull, DF Wiemer, RJ Hohl
Journal of lipid research 52 (11), 1957-1964, 2011
412011
PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae
HJ Cui, XG Liu, M McCormick, BM Wasko, W Zhao, X He, Y Yuan, ...
Age 37, 1-8, 2015
372015
End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging
JR Delaney, A Chou, B Olsen, D Carr, C Murakami, U Ahmed, S Sim, ...
FEMS yeast research 13 (3), 267-276, 2013
372013
Synthesis and biological evaluation of a series of aromatic bisphosphonates
RJ Barney, BM Wasko, A Dudakovic, RJ Hohl, DF Wiemer
Bioorganic & medicinal chemistry 18 (20), 7212-7220, 2010
362010
Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism
R Yu, X Cao, L Sun, J Zhu, BM Wasko, W Liu, E Crutcher, H Liu, MC Jo, ...
Nature Communications 12 (1), 1981, 2021
322021
Yeast as a model to understand the interaction between genotype and the response to calorie restriction
J Schleit, BM Wasko, M Kaeberlein
FEBS letters 586 (18), 2868-2873, 2012
292012
Buffering the pH of the culture medium does not extend yeast replicative lifespan
BM Wasko, DT Carr, H Tung, H Doan, N Schurman, JR Neault, J Feng, ...
F1000Research 2, 2013
282013
CAN1 arginine permease deficiency extends yeast replicative lifespan via translational activation of stress response genes
C Beaupere, BM Wasko, J Lorusso, BK Kennedy, M Kaeberlein, ...
Cell reports 18 (8), 1884-1892, 2017
232017
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