karen duff
karen duff
Підтверджена електронна адреса в columbia.edu
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy, 1-382, 2021
71202021
Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
D Morgan, DM Diamond, PE Gottschall, KE Ugen, C Dickey, J Hardy, ...
Nature 408 (6815), 982-985, 2000
19552000
Increased amyloid-β42 (43) in brains of mice expressing mutant presenilin 1
K Duff, C Eckman, C Zehr, X Yu, CM Prada, J Perez-Tur, M Hutton, L Buee, ...
Nature 383 (6602), 710-713, 1996
18361996
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
L Holcomb, MN Gordon, E McGowan, X Yu, S Benkovic, P Jantzen, ...
Nature medicine 4 (1), 97-100, 1998
15111998
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
J Lewis, E McGowan, J Rockwood, H Melrose, P Nacharaju, ...
Nature genetics 25 (4), 402-405, 2000
13472000
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
LM Refolo, MA Pappolla, B Malester, J LaFrancois, T Bryant-Thomas, ...
Neurobiology of disease 7 (4), 321-331, 2000
11632000
Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
WH Yu, AM Cuervo, A Kumar, CM Peterhoff, SD Schmidt, JH Lee, ...
The Journal of cell biology 171 (1), 87-98, 2005
9562005
Trans-synaptic spread of tau pathology in vivo
L Liu, V Drouet, JW Wu, MP Witter, SA Small, C Clelland, K Duff
PloS one 7 (2), e31302, 2012
8372012
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
W Noble, E Planel, C Zehr, V Olm, J Meyerson, F Suleman, K Gaynor, ...
Proceedings of the national academy of sciences 102 (19), 6990-6995, 2005
7702005
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration
CA Saura, SY Choi, V Beglopoulos, S Malkani, D Zhang, BSS Rao, ...
Neuron 42 (1), 23-36, 2004
7602004
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
C Andorfer, Y Kress, M Espinoza, R De Silva, KL Tucker, YA Barde, K Duff, ...
Journal of neurochemistry 86 (3), 582-590, 2003
6592003
A cholesterol-lowering drug reduces β-amyloid pathology in a transgenic mouse model of Alzheimer's disease
LM Refolo, MA Pappolla, J LaFrancois, B Malester, SD Schmidt, ...
Neurobiology of disease 8 (5), 890-899, 2001
6312001
Linking Aβ and tau in late-onset Alzheimer's disease: a dual pathway hypothesis
SA Small, K Duff
Neuron 60 (4), 534-542, 2008
5802008
Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches
J Tsai, J Grutzendler, K Duff, WB Gan
Nature neuroscience 7 (11), 1181-1183, 2004
5572004
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
C Andorfer, CM Acker, Y Kress, PR Hof, K Duff, P Davies
Journal of Neuroscience 25 (22), 5446-5454, 2005
5052005
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
W Noble, V Olm, K Takata, E Casey, O Mary, J Meyerson, K Gaynor, ...
Neuron 38 (4), 555-565, 2003
4962003
Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau
J Hardy, K Duff, KG Hardy, J Perez-Tur, M Hutton
Nature neuroscience 1 (5), 355-358, 1998
4271998
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits
LA Holcomb, MN Gordon, P Jantzen, K Hsiao, K Duff, D Morgan
Behavior genetics 29 (3), 177-185, 1999
4101999
Comparative lipidomic analysis of mouse and human brain with Alzheimer disease
RB Chan, TG Oliveira, EP Cortes, LS Honig, KE Duff, SA Small, MR Wenk, ...
Journal of Biological Chemistry 287 (4), 2678-2688, 2012
3802012
Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease
UA Khan, L Liu, FA Provenzano, DE Berman, CP Profaci, R Sloan, ...
Nature neuroscience 17 (2), 304-311, 2014
3792014
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