Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5364 | 2018 |
The many roles of FAS receptor signaling in the immune system A Strasser, PJ Jost, S Nagata Immunity 30 (2), 180-192, 2009 | 1148 | 2009 |
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 L Galluzzi, BS Pedro, I Vitale, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 22 (1), 58-73, 2015 | 1146 | 2015 |
Aberrant NF-κB signaling in lymphoma: mechanisms, consequences, and therapeutic implications PJ Jost, J Ruland Blood 109 (7), 2700-2707, 2007 | 585 | 2007 |
XIAP discriminates between type I and type II FAS-induced apoptosis PJ Jost, S Grabow, D Gray, MD McKenzie, U Nachbur, DCS Huang, ... Nature 460 (7258), 1035-1039, 2009 | 580 | 2009 |
Fas death receptor signalling: roles of Bid and XIAP T Kaufmann, A Strasser, PJ Jost Cell Death & Differentiation 19 (1), 42-50, 2012 | 451 | 2012 |
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity RB Damgaard, U Nachbur, M Yabal, WWL Wong, BK Fiil, M Kastirr, ... Molecular cell 46 (6), 746-758, 2012 | 404 | 2012 |
XIAP restricts TNF-and RIP3-dependent cell death and inflammasome activation M Yabal, N Müller, H Adler, N Knies, CJ Groß, RB Damgaard, ... Cell reports 7 (6), 1796-1808, 2014 | 258 | 2014 |
Mcl-1 is essential for germinal center formation and B cell memory I Vikstrom, S Carotta, K Lüthje, V Peperzak, PJ Jost, S Glaser, ... Science 330 (6007), 1095-1099, 2010 | 247 | 2010 |
Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor κB–dependent inflammation in monocytes R Schmidt, A Bültmann, S Fischel, A Gillitzer, P Cullen, A Walch, P Jost, ... Circulation research 102 (3), 302-309, 2008 | 201 | 2008 |
RIPK3 restricts myeloid leukemogenesis by promoting cell death and differentiation of leukemia initiating cells U Höckendorf, M Yabal, T Herold, E Munkhbaatar, S Rott, S Jilg, ... Cancer cell 30 (1), 75-91, 2016 | 181 | 2016 |
cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1-and RIPK3-dependent manner WWL Wong, JE Vince, N Lalaoui, KE Lawlor, D Chau, A Bankovacki, ... Blood, The Journal of the American Society of Hematology 123 (16), 2562-2572, 2014 | 171 | 2014 |
Fatal hepatitis mediated by tumor necrosis factor TNFα requires caspase-8 and involves the BH3-only proteins Bid and Bim T Kaufmann, PJ Jost, M Pellegrini, H Puthalakath, R Gugasyan, ... Immunity 30 (1), 56-66, 2009 | 157 | 2009 |
Comprehensive genomic and transcriptomic analysis for guiding therapeutic decisions in patients with rare cancers P Horak, C Heining, S Kreutzfeldt, B Hutter, A Mock, J Hüllein, M Fröhlich, ... Cancer discovery 11 (11), 2780-2795, 2021 | 154 | 2021 |
CYLD limits Lys63-and Met1-linked ubiquitin at receptor complexes to regulate innate immune signaling M Hrdinka, BK Fiil, M Zucca, D Leske, K Bagola, M Yabal, PR Elliott, ... Cell reports 14 (12), 2846-2858, 2016 | 153 | 2016 |
Disease‐causing mutations in the XIAP BIR 2 domain impair NOD 2‐dependent immune signalling RB Damgaard, BK Fiil, C Speckmann, M Yabal, U Stadt, S Bekker‐Jensen, ... EMBO molecular medicine 5 (8), 1278-1295, 2013 | 150 | 2013 |
A dual role of caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development Y Boege, M Malehmir, ME Healy, K Bettermann, A Lorentzen, M Vucur, ... Cancer cell 32 (3), 342-359. e10, 2017 | 144 | 2017 |
XIAP loss triggers RIPK3-and caspase-8-driven IL-1β activation and cell death as a consequence of TLR-MyD88-induced cIAP1-TRAF2 degradation KE Lawlor, R Feltham, M Yabal, SA Conos, KW Chen, S Ziehe, C Graß, ... Cell reports 20 (3), 668-682, 2017 | 130 | 2017 |
Survival outcomes associated with 3 years vs 1 year of adjuvant imatinib for patients with high-risk gastrointestinal stromal tumors: an analysis of a randomized clinical trial … H Joensuu, M Eriksson, KS Hall, A Reichardt, B Hermes, J Schütte, ... JAMA oncology 6 (8), 1241-1246, 2020 | 126 | 2020 |
Blockade of BCL-2 proteins efficiently induces apoptosis in progenitor cells of high-risk myelodysplastic syndromes patients S Jilg, V Reidel, C Müller-Thomas, J König, J Schauwecker, U Höckendorf, ... Leukemia 30 (1), 112-123, 2016 | 126 | 2016 |