Підписатись
Claus J. Løland
Claus J. Løland
Підтверджена електронна адреса в sund.ku.dk - Домашня сторінка
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SLC6 neurotransmitter transporters: structure, function, and regulation
AS Kristensen, J Andersen, TN Jørgensen, L Sørensen, J Eriksen, ...
Pharmacological reviews 63 (3), 585-640, 2011
8732011
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, R Chandra, MA Goren, ...
Nature methods 7 (12), 1003-1008, 2010
5182010
The binding sites for cocaine and dopamine in the dopamine transporter overlap
T Beuming, J Kniazeff, ML Bergmann, L Shi, L Gracia, K Raniszewska, ...
Nature neuroscience 11 (7), 780-789, 2008
4102008
N-terminal truncation of the dopamine transporter abolishes phorbol ester-and substance P receptor-stimulated phosphorylation without impairing transporter internalization
C Grånäs, J Ferrer, CJ Loland, JA Javitch, U Gether
Journal of Biological Chemistry 278 (7), 4990-5000, 2003
2132003
Generation of an activating Zn2+ switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the …
CJ Loland, L Norregaard, T Litman, U Gether
Proceedings of the National Academy of Sciences 99 (3), 1683-1688, 2002
1622002
Missense dopamine transporter mutations associate with adult parkinsonism and ADHD
FH Hansen, T Skjørringe, S Yasmeen, NV Arends, MA Sahai, K Erreger, ...
The Journal of clinical investigation 124 (7), 3107-3120, 2014
1532014
Defining proximity relationships in the tertiary structure of the dopamine transporter: Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn2+ …
CJ Loland, L Norregaard, U Gether
Journal of Biological Chemistry 274 (52), 36928-36934, 1999
1511999
R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse
CJ Loland, M Mereu, OM Okunola, J Cao, TE Prisinzano, S Mazier, ...
Biological psychiatry 72 (5), 405-413, 2012
1482012
A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins
PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, AC Kruse, A Manglik, ...
Chemistry–A European Journal 18 (31), 9485-9490, 2012
1482012
An intracellular interaction network regulates conformational transitions in the dopamine transporter
J Kniazeff, L Shi, CJ Loland, JA Javitch, H Weinstein, U Gether
Journal of Biological Chemistry 283 (25), 17691-17701, 2008
1462008
Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors
CJ Loland, RI Desai, MF Zou, J Cao, P Grundt, K Gerstbrein, HH Sitte, ...
Molecular pharmacology 73 (3), 813-823, 2008
1452008
Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding
CJ Loland, C Grånäs, JA Javitch, U Gether
Journal of Biological Chemistry 279 (5), 3228-3238, 2004
1212004
Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions
C Bjerggaard, JU Fog, H Hastrup, K Madsen, CJ Loland, JA Javitch, ...
Journal of Neuroscience 24 (31), 7024-7036, 2004
1142004
Regulation of dopamine transporter trafficking by intracellular amphetamine
KM Kahlig, BJ Lute, Y Wei, CJ Loland, U Gether, JA Javitch, A Galli
Molecular pharmacology 70 (2), 542-548, 2006
992006
Tandem facial amphiphiles for membrane protein stabilization
PS Chae, K Gotfryd, J Pacyna, LJW Miercke, SGF Rasmussen, ...
Journal of the American Chemical Society 132 (47), 16750-16752, 2010
982010
Steric hindrance mutagenesis in the conserved extracellular vestibule impedes allosteric binding of antidepressants to the serotonin transporter
P Plenge, L Shi, T Beuming, J Te, AH Newman, H Weinstein, U Gether, ...
Journal of Biological Chemistry 287 (47), 39316-39326, 2012
922012
Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study
PS Chae, RR Rana, K Gotfryd, SGF Rasmussen, AC Kruse, KH Cho, ...
Chemical communications 49 (23), 2287-2289, 2013
852013
The binding sites for benztropines and dopamine in the dopamine transporter overlap
H Bisgaard, MAB Larsen, S Mazier, T Beuming, AH Newman, H Weinstein, ...
Neuropharmacology 60 (1), 182-190, 2011
672011
Novel and high affinity 2-[(diphenylmethyl) sulfinyl] acetamide (modafinil) analogues as atypical dopamine transporter inhibitors
J Cao, RD Slack, OM Bakare, C Burzynski, R Rais, BS Slusher, T Kopajtic, ...
Journal of medicinal chemistry 59 (23), 10676-10691, 2016
662016
Conformational dynamics of the human serotonin transporter during substrate and drug binding
IR Möller, M Slivacka, AK Nielsen, SGF Rasmussen, U Gether, CJ Loland, ...
Nature communications 10 (1), 1687, 2019
642019
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