| Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19 T Herold, V Jurinovic, C Arnreich, BJ Lipworth, JC Hellmuth, ... Journal of Allergy and Clinical Immunology 146 (1), 128-136. e4, 2020 | 1069 | 2020 |
| A 17-gene stemness score for rapid determination of risk in acute leukaemia SWK Ng, A Mitchell, JA Kennedy, WC Chen, J McLeod, N Ibrahimova, ... Nature 540 (7633), 433-437, 2016 | 761 | 2016 |
| Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia KH Metzeler, T Herold, M Rothenberg-Thurley, S Amler, MC Sauerland, ... Blood, The Journal of the American Society of Hematology 128 (5), 686-698, 2016 | 570 | 2016 |
| COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus L Scarfò, T Chatzikonstantinou, GM Rigolin, G Quaresmini, M Motta, ... Leukemia 34 (9), 2354-2363, 2020 | 257 | 2020 |
| Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML S Haubner, F Perna, T Köhnke, C Schmidt, S Berman, C Augsberger, ... Leukemia 33 (1), 64-74, 2019 | 255 | 2019 |
| Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia T Herold, M Rothenberg-Thurley, VV Grunwald, H Janke, D Goerlich, ... Leukemia 34 (12), 3161-3172, 2020 | 190 | 2020 |
| GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo C Pabst, A Bergeron, VP Lavallée, J Yeh, P Gendron, GL Norddahl, ... Blood, The Journal of the American Society of Hematology 127 (16), 2018-2027, 2016 | 188 | 2016 |
| Level of IL-6 predicts respiratory failure in hospitalized symptomatic COVID-19 patients T Herold, V Jurinovic, C Arnreich, JC Hellmuth, M von Bergwelt-Baildon, ... MedRxiv, 2020.04. 01.20047381, 2020 | 186 | 2020 |
| Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study Z Li, T Herold, C He, PJM Valk, P Chen, V Jurinovic, U Mansmann, ... Journal of clinical oncology 31 (9), 1172, 2013 | 184 | 2013 |
| RIPK3 restricts myeloid leukemogenesis by promoting cell death and differentiation of leukemia initiating cells U Höckendorf, M Yabal, T Herold, E Munkhbaatar, S Rott, S Jilg, ... Cancer cell 30 (1), 75-91, 2016 | 180 | 2016 |
| GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia PA Greif, A Dufour, NP Konstandin, B Ksienzyk, E Zellmeier, B Tizazu, ... Blood, The Journal of the American Society of Hematology 120 (2), 395-403, 2012 | 180 | 2012 |
| Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis T Herold, S Schneider, KH Metzeler, M Neumann, L Hartmann, ... haematologica 102 (1), 130, 2017 | 171 | 2017 |
| Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia M Rothenberg-Thurley, S Amler, D Goerlich, T Köhnke, NP Konstandin, ... Leukemia, 1-27, 2017 | 142 | 2017 |
| miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia X Jiang, C Hu, S Arnovitz, J Bugno, M Yu, Z Zuo, P Chen, H Huang, ... Nature communications 7 (1), 11452, 2016 | 139 | 2016 |
| RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes PA Greif, NP Konstandin, KH Metzeler, T Herold, Z Pasalic, B Ksienzyk, ... Haematologica 97 (12), 1909, 2012 | 119 | 2012 |
| Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis T Herold, KH Metzeler, S Vosberg, L Hartmann, C Röllig, F Stölzel, ... Blood, The Journal of the American Society of Hematology 124 (8), 1304-1311, 2014 | 111 | 2014 |
| Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older VV Prassek, M Rothenberg-Thurley, MC Sauerland, T Herold, H Janke, ... haematologica 103 (11), 1853, 2018 | 103 | 2018 |
| A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia T Herold, V Jurinovic, AMN Batcha, SA Bamopoulos, ... haematologica 103 (3), 456, 2018 | 102 | 2018 |
| Ph-like acute lymphoblastic leukemia in older adults T Herold, CD Baldus, N Gökbuget New England Journal of Medicine 371 (23), 2235-2235, 2014 | 85 | 2014 |
| Evolution of cytogenetically normal acute myeloid leukemia during therapy and relapse: an exome sequencing study of 50 patients PA Greif, L Hartmann, S Vosberg, SM Stief, R Mattes, I Hellmann, ... Clinical cancer research 24 (7), 1716-1726, 2018 | 83 | 2018 |
Klaus H. MetzelerUniversity Hospital Leipzig, GermanyVerified email at klaus-metzeler.de
