Підписатись
Israel Cañadas
Israel Cañadas
Assistant Professor, Fox Chase Cancer Center
Підтверджена електронна адреса в fccc.edu
Назва
Посилання
Посилання
Рік
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
10112018
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ...
Cancer discovery 8 (2), 196-215, 2018
4332018
Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer
S Arena, B Bellosillo, G Siravegna, A Martínez, I Canadas, L Lazzari, ...
Clinical cancer research 21 (9), 2157-2166, 2015
2802015
Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses
I Cañadas, R Thummalapalli, JW Kim, S Kitajima, RW Jenkins, ...
Nature medicine 24 (8), 1143-1150, 2018
2432018
3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade
AR Aref, M Campisi, E Ivanova, A Portell, D Larios, BP Piel, N Mathur, ...
Lab on a Chip 18 (20), 3129-3143, 2018
2132018
Increased ALK gene copy number and amplification are frequent in non-small cell lung cancer
M Salido, L Pijuan, L Martínez-Avilés, AB Galván, I Cañadas, A Rovira, ...
Journal of thoracic oncology 6 (1), 21-27, 2011
1812011
Targeting epithelial-to-mesenchymal transition with Met inhibitors reverts chemoresistance in small cell lung cancer
I Canadas, F Rojo, Á Taus, O Arpí, M Arumí-Uría, L Pijuan, S Menéndez, ...
Clinical Cancer Research 20 (4), 938-950, 2014
1422014
EZH2 inhibition activates a dsRNA–STING–interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer
KL Morel, AV Sheahan, DL Burkhart, SC Baca, N Boufaied, Y Liu, X Qiu, ...
Nature cancer 2 (4), 444-456, 2021
1372021
The long and short non-coding RNAs modulating EZH2 signaling in cancer
S Mirzaei, MH Gholami, K Hushmandi, F Hashemi, A Zabolian, I Canadas, ...
Journal of hematology & oncology 15 (1), 18, 2022
1022022
Autophagy inhibition dysregulates TBK1 signaling and promotes pancreatic inflammation
S Yang, Y Imamura, RW Jenkins, I Cañadas, S Kitajima, A Aref, ...
Cancer immunology research 4 (6), 520-530, 2016
1022016
Intrinsic immunogenicity of small cell lung carcinoma revealed by its cellular plasticity
NR Mahadevan, EH Knelson, JO Wolff, A Vajdi, M Saigí, M Campisi, ...
Cancer discovery 11 (8), 1952-1969, 2021
932021
The first-in-class anti-EGFR antibody mixture Sym004 overcomes cetuximab resistance mediated by EGFR extracellular domain mutations in colorectal cancer
FJ Sánchez-Martín, B Bellosillo, M Gelabert-Baldrich, A Dalmases, ...
Clinical Cancer Research 22 (13), 3260-3267, 2016
692016
C-MET as a new therapeutic target for the development of novel anticancer drugs
I Canadas, F Rojo, M Arumí-Uría, A Rovira, J Albanell, E Arriola
Clinical and Translational Oncology 12, 253-260, 2010
632010
MET expression and copy number heterogeneity in nonsquamous non-small cell lung cancer (nsNSCLC)
D Casadevall, J Gimeno, S Clavé, Á Taus, L Pijuan, M Arumí, M Lorenzo, ...
Oncotarget 6 (18), 16215, 2015
622015
MET phosphorylation predicts poor outcome in small cell lung carcinoma and its inhibition blocks HGF-induced effects in MET mutant cell lines
E Arriola, I Canadas, M Arumí-Uría, M Dómine, JA Lopez-Vilariño, O Arpí, ...
British journal of cancer 105 (6), 814-823, 2011
602011
Tumor-derived cGAMP regulates activation of the vasculature
M Campisi, SK Sundararaman, SE Shelton, EH Knelson, NR Mahadevan, ...
Frontiers in Immunology 11, 2090, 2020
472020
Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence
Z Wu, J Zhou, X Zhang, Z Zhang, Y Xie, J Liu, ZV Ho, A Panda, X Qiu, ...
Nature genetics 53 (6), 881-894, 2021
462021
High circulating hepatocyte growth factor levels associate with epithelial to mesenchymal transition and poor outcome in small cell lung cancer patients
I Cañadas, Á Taus, I González, X Villanueva, J Gimeno, L Pijuan, ...
Oncotarget 5 (14), 5246, 2014
432014
Molecular and genomic determinants of response to immune checkpoint inhibition in cancer
RW Jenkins, R Thummalapalli, J Carter, I Cañadas, DA Barbie
Annual Review of Medicine 69, 333-347, 2018
422018
Genetic changes in small cell lung carcinoma
E Arriola, I Cañadas, M Arumí, F Rojo, A Rovira, J Albanell
Clinical and Translational Oncology 10, 189-197, 2008
402008
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