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Kai Hu
Kai Hu
Подтвержден адрес электронной почты в домене imperial.ac.uk
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Процитировано
Год
Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice
PF McKay, K Hu, AK Blakney, K Samnuan, JC Brown, R Penn, J Zhou, ...
Nature communications 11 (1), 3523, 2020
4062020
CCL19 and CCR7 expression, signaling pathways, and adjuvant functions in viral infection and prevention
Y Yan, R Chen, X Wang, K Hu, L Huang, M Lu, Q Hu
Frontiers in cell and developmental biology 7, 212, 2019
1282019
Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice
AJ Spencer, PF McKay, S Belij-Rammerstorfer, M Ulaszewska, CD Bissett, ...
Nature communications 12 (1), 2893, 2021
1262021
Big is beautiful: enhanced saRNA delivery and immunogenicity by a higher molecular weight, bioreducible, cationic polymer
AK Blakney, Y Zhu, PF McKay, CR Bouton, J Yeow, J Tang, K Hu, ...
ACS nano 14 (5), 5711-5727, 2020
1202020
Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial
KM Pollock, HM Cheeseman, AJ Szubert, V Libri, M Boffito, D Owen, ...
EClinicalMedicine 44, 2022
952022
Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines
AK Blakney, PF McKay, K Hu, K Samnuan, N Jain, A Brown, A Thomas, ...
Journal of controlled release 338, 201-210, 2021
622021
DC-SIGN as an attachment factor mediates Japanese encephalitis virus infection of human dendritic cells via interaction with a single high-mannose residue of viral E glycoprotein
P Wang, K Hu, S Luo, M Zhang, X Deng, C Li, W Jin, B Hu, S He, M Li, ...
Virology 488, 108-119, 2016
602016
Herpes simplex virus type 2 infection of human epithelial cells induces CXCL9 expression and CD4+ T cell migration via activation of p38-CCAAT/enhancer-binding protein-β pathway
W Huang, K Hu, S Luo, M Zhang, C Li, W Jin, Y Liu, GE Griffin, ...
The Journal of Immunology 188 (12), 6247-6257, 2012
582012
Highly conserved HIV-1 gp120 glycans proximal to CD4-binding region affect viral infectivity and neutralizing antibody induction
X Huang, W Jin, K Hu, S Luo, T Du, GE Griffin, RJ Shattock, Q Hu
Virology 423 (1), 97-106, 2012
542012
CCL19 and CCL28 augment mucosal and systemic immune responses to HIV-1 gp140 by mobilizing responsive immunocytes into secondary lymph nodes and mucosal tissue
K Hu, S Luo, L Tong, X Huang, W Jin, W Huang, T Du, Y Yan, S He, ...
The Journal of Immunology 191 (4), 1935-1947, 2013
512013
Innate inhibiting proteins enhance expression and immunogenicity of self-amplifying RNA
AK Blakney, PF McKay, CR Bouton, K Hu, K Samnuan, RJ Shattock
Molecular Therapy 29 (3), 1174-1185, 2021
472021
HSV-2 immediate-early protein US1 inhibits IFN-β production by suppressing association of IRF-3 with IFN-β promoter
M Zhang, Y Liu, P Wang, X Guan, S He, S Luo, C Li, K Hu, W Jin, T Du, ...
The Journal of Immunology 194 (7), 3102-3115, 2015
442015
Contribution of N-linked glycans on HSV-2 gB to cell–cell fusion and viral entry
S Luo, K Hu, S He, P Wang, M Zhang, X Huang, T Du, C Zheng, Y Liu, ...
Virology 483, 72-82, 2015
372015
Tick-borne encephalitis virus nonstructural protein NS5 induces RANTES expression dependent on the RNA-dependent RNA polymerase activity
Z Zheng, J Yang, X Jiang, Y Liu, X Zhang, M Li, M Zhang, M Fu, K Hu, ...
The Journal of Immunology 201 (1), 53-68, 2018
302018
Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine induces equivalent preclinical antibody titers and viral neutralization to recovered COVID-19 patients
PF McKay, K Hu, AK Blakney, K Samnuan, CR Bouton, P Rogers, K Polra, ...
BioRXiv, 2020.04. 22.055608, 2020
292020
DC-SIGN plays a stronger role than DCIR in mediating HIV-1 capture and transfer
W Jin, C Li, T Du, K Hu, X Huang, Q Hu
Virology 458, 83-92, 2014
272014
Bifunctional CD4–DC-SIGN Fusion Proteins Demonstrate Enhanced Avidity to gp120 and Inhibit HIV-1 Infection and Dissemination
T Du, K Hu, J Yang, J Jin, C Li, D Stieh, GE Griffin, RJ Shattock, Q Hu
Antimicrobial agents and chemotherapy 56 (9), 4640-4649, 2012
272012
Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4+ T Cell Migration and Is Regulated by the Viral Immediate-Early …
M Zhang, X Deng, X Guan, L Geng, M Fu, B Zhang, R Chen, H Hu, K Hu, ...
Frontiers in immunology 9, 2932, 2018
202018
Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice. Nat. Commun. 11, 3523
PF McKay, K Hu, AK Blakney, K Samnuan, JC Brown, R Penn, J Zhou, ...
192020
Immunization with HSV-2 gB-CCL19 fusion constructs protects mice against lethal vaginal challenge
Y Yan, K Hu, X Deng, X Guan, S Luo, L Tong, T Du, M Fu, M Zhang, Y Liu, ...
The Journal of Immunology 195 (1), 329-338, 2015
182015
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