Immunopathology of multiple sclerosis CA Dendrou, L Fugger, MA Friese Nature Reviews Immunology 15 (9), 545-558, 2015 | 2490 | 2015 |
HLA variation and disease CA Dendrou, J Petersen, J Rossjohn, L Fugger Nature Reviews Immunology 18 (5), 325-339, 2018 | 601 | 2018 |
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis AP Gregory, CA Dendrou, KE Attfield, A Haghikia, DK Xifara, F Butter, ... Nature 488 (7412), 508-511, 2012 | 436 | 2012 |
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders JC Taylor, HC Martin, S Lise, J Broxholme, JB Cazier, A Rimmer, ... Nature genetics 47 (7), 717-726, 2015 | 398 | 2015 |
Class II HLA interactions modulate genetic risk for multiple sclerosis Nature genetics 47 (10), 1107-1113, 2015 | 381 | 2015 |
Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource CA Dendrou, V Plagnol, E Fung, JHM Yang, K Downes, JD Cooper, ... Nature genetics 41 (9), 1011-1015, 2009 | 303 | 2009 |
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity CA Dendrou, A Cortes, L Shipman, HG Evans, KE Attfield, L Jostins, ... Science translational medicine 8 (363), 363ra149-363ra149, 2016 | 224 | 2016 |
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ... Cell 185 (5), 916-938. e58, 2022 | 152 | 2022 |
An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease Y Peng, SL Felce, D Dong, F Penkava, AJ Mentzer, X Yao, G Liu, Z Yin, ... Nature immunology 23 (1), 50-61, 2022 | 133 | 2022 |
T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion B Morriswood, G Ryzhakov, C Puri, SD Arden, R Roberts, C Dendrou, ... Journal of cell science 120 (15), 2574-2585, 2007 | 110 | 2007 |
Structural and regulatory diversity shape HLA-C protein expression levels G Kaur, S Gras, JI Mobbs, JP Vivian, A Cortes, T Barber, SB Kuttikkatte, ... Nature communications 8 (1), 15924, 2017 | 105 | 2017 |
The IL-2/CD25 pathway determines susceptibility to T1D in humans and NOD mice CA Dendrou, LS Wicker Journal of clinical immunology 28, 685-696, 2008 | 68 | 2008 |
Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors ML Pekalski, RC Ferreira, RMR Coulson, AJ Cutler, H Guo, DJ Smyth, ... The Journal of Immunology 190 (6), 2554-2566, 2013 | 67 | 2013 |
Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank A Cortes, CA Dendrou, A Motyer, L Jostins, D Vukcevic, A Dilthey, ... Nature Genetics 49 (9), 1311-1318, 2017 | 66 | 2017 |
Identification of early neurodegenerative pathways in progressive multiple sclerosis M Kaufmann, AL Schaupp, R Sun, F Coscia, CA Dendrou, A Cortes, ... Nature Neuroscience 25 (7), 944-955, 2022 | 65 | 2022 |
Severe B-cell-mediated CNS disease secondary to alemtuzumab therapy A Haghikia, CA Dendrou, R Schneider, T Grüter, T Postert, M Matzke, ... The Lancet Neurology 16 (2), 104-106, 2017 | 65 | 2017 |
Immunomodulation in multiple sclerosis: promises and pitfalls CA Dendrou, L Fugger Current opinion in immunology 49, 37-43, 2017 | 56 | 2017 |
Identifying cross-disease components of genetic risk across hospital data in the UK Biobank A Cortes, PK Albers, CA Dendrou, L Fugger, G McVean Nature genetics 52 (1), 126-134, 2020 | 38 | 2020 |
Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene HI Fraser, CA Dendrou, B Healy, DB Rainbow, S Howlett, LJ Smink, ... The Journal of Immunology 184 (9), 5075-5084, 2010 | 34 | 2010 |
Neuroinflammation—using big data to inform clinical practice CA Dendrou, G McVean, L Fugger Nature Reviews Neurology 12 (12), 685-698, 2016 | 30 | 2016 |