| Brassinosteroids regulate pectin methylesterase activity and AtPME41 expression in Arabidopsis under chilling stress T Qu, R Liu, W Wang, L An, T Chen, G Liu, Z Zhao Cryobiology 63 (2), 111-117, 2011 | 113 | 2011 |
| Molecular basis of ligand dissociation from the adenosine A2A receptor D Guo, AC Pan, RO Dror, T Mocking, R Liu, LH Heitman, DE Shaw, ... Molecular pharmacology 89 (5), 485-491, 2016 | 88 | 2016 |
| Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A2A Receptor T Amelia, JPD van Veldhoven, M Falsini, R Liu, LH Heitman, ... Journal of Medicinal Chemistry 64 (7), 3827-3842, 2021 | 34 | 2021 |
| Human G protein-coupled receptor studies in Saccharomyces cerevisiae R Liu, W Wong, AP IJzerman Biochemical Pharmacology 114, 103-115, 2016 | 33 | 2016 |
| Scanning mutagenesis in a yeast system delineates the role of the NPxxY (x) 5, 6F motif and helix 8 of the adenosine A2B receptor in G protein coupling R Liu, D Nahon, B le Roy, EB Lenselink, AP IJzerman Biochemical pharmacology 95 (4), 290-300, 2015 | 30 | 2015 |
| A yeast screening method to decipher the interaction between the adenosine A2B receptor and the C-terminus of different G protein α-subunits R Liu, NJA Groenewoud, MC Peeters, EB Lenselink, AP IJzerman Purinergic signalling 10, 441-453, 2014 | 30 | 2014 |
| Long residence time adenosine A1 receptor agonists produce sustained wash-resistant antilipolytic effect in rat adipocytes YI Yun, J Chen, R Liu, W Chen, C Liu, R Wang, Z Hou, Z Yu, Y Sun, ... Biochemical Pharmacology 164, 45-52, 2019 | 18 | 2019 |
| Rollover cyclometalation vs nitrogen coordination in tetrapyridyl anticancer gold (III) complexes: Effect on protein interaction and toxicity XQ Zhou, I Carbo-Bague, MA Siegler, J Hilgendorf, U Basu, I Ott, R Liu, ... JACS Au 1 (4), 380-395, 2021 | 15 | 2021 |
| Affinity and kinetics study of anthranilic acids as HCA2 receptor agonists JPD van Veldhoven, R Liu, SA Thee, Y Wouters, SJM Verhoork, ... Bioorganic & Medicinal Chemistry 23 (14), 4013-4025, 2015 | 11 | 2015 |
| Targeting the Kv11. 1 (hERG) channel with allosteric modulators. Synthesis and biological evaluation of three novel series of LUF7346 derivatives JPD van Veldhoven, G Campostrini, CJE van Gessel, ... European Journal of Medicinal Chemistry 212, 113033, 2021 | 7 | 2021 |
| A Chemical Biological Approach to Study G Protein-Coupled Receptors: Labeling the Adenosine A1 Receptor Using an Electrophilic Covalent Probe BLH Beerkens, C Koc, R Liu, BI Florea, SE Le Dévédec, LH Heitman, ... ACS Chemical Biology 17 (11), 3131-3139, 2022 | 6 | 2022 |
| Successive statistical and structure-based modeling to identify chemically novel kinase inhibitors L Burggraaff, EB Lenselink, W Jespers, J van Engelen, BJ Bongers, ... Journal of Chemical Information and Modeling 60 (9), 4283-4295, 2020 | 6 | 2020 |
| The role of the C-terminus of the human hydroxycarboxylic acid receptors 2 and 3 in G protein activation using Gα-engineered yeast cells R Liu, JPD van Veldhoven, AP IJzerman European journal of pharmacology 770, 70-77, 2016 | 6 | 2016 |
| A multiple classifier system identifies novel cannabinoid CB2 receptor ligands D Ruano-Ordás, L Burggraaff, R Liu, C van der Horst, LH Heitman, ... Journal of Cheminformatics 11, 1-14, 2019 | 4 | 2019 |
| Microwave-Assisted Synthesis, Structure, and Preliminary Biological Evaluation of Novel 6-Methoxy-5, 6-dihydro-5-azapurines AI Siutkina, S Kalinina, R Liu, LH Heitman, A Junker, CG Daniliuc, ... ACS omega 8 (15), 14097-14112, 2023 | 3 | 2023 |
| Cancer-Associated Mutations of the Adenosine A2A Receptor Have Diverse Influences on Ligand Binding and Receptor Functions C Feng, X Wang, W Jespers, R Liu, SD Zamarbide Losada, ... Molecules 27 (15), 4676, 2022 | 3 | 2022 |
| Impedance-based phenotypic readout of transporter function: a case for glutamate transporters HJ Sijben, L Dall’Acqua, R Liu, A Jarret, E Christodoulaki, S Onstein, ... Frontiers in Pharmacology 13, 872335, 2022 | 3 | 2022 |
| P Molecular Insights into Disease-Associated Glutamate Transporter (EAAT1/SLC1A3) Variants Using in Silico and in Vitro Approaches M Gorostiola González, HJ Sijben, L Dall Acqua, R Liu, AP IJzerman, ... Front. Mol. Biosci 10 (128667310.3389), 2023 | 2 | 2023 |
| Development of Bicyclo[3.1.0]hexane-Based A3 Receptor Ligands: Closing the Gaps in the Structure–Affinity Relationships JP Lemmerhirt, A Isaak, R Liu, M Kock, CG Daniliuc, KA Jacobson, ... Molecules 27 (7), 2283, 2022 | 2 | 2022 |
| Development of subtype-selective covalent ligands for the adenosine A 2B receptor by tuning the reactive group BLH Beerkens, X Wang, M Avgeropoulou, LN Adistia, JPD van Veldhoven, ... RSC Medicinal Chemistry 13 (7), 850-856, 2022 | 2 | 2022 |
Eelke Bart LenselinkGalapagosVerified email at glpg.com
Eelke Bart LenselinkGalapagosVerified email at glpg.com