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Brian Estevez
Brian Estevez
Children's Hospital of Philadelphi
Verified email at email.chop.edu
Title
Cited by
Cited by
Year
New concepts and mechanisms of platelet activation signaling
B Estevez, X Du
Physiology 32 (2), 162-177, 2017
3452017
Targeting integrin and integrin signaling in treating thrombosis
B Estevez, B Shen, X Du
Arteriosclerosis, thrombosis, and vascular biology 35 (1), 24-29, 2015
1382015
Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells
C Penaloza, B Estevez, S Orlanski, M Sikorska, R Walker, C Smith, ...
The FASEB Journal 23 (6), 1869, 2009
1352009
Differential roles of the NADPH-oxidase 1 and 2 in platelet activation and thrombosis
MK Delaney, K Kim, B Estevez, Z Xu, A Stojanovic-Terpo, B Shen, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (5), 846-854, 2016
1192016
Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation
B Estevez, K Kim, MK Delaney, A Stojanovic-Terpo, B Shen, C Ruan, ...
Blood, The Journal of the American Society of Hematology 127 (5), 626-636, 2016
862016
Sex-dependent regulation of cytochrome P450 family members Cyp1a1, Cyp2e1, and Cyp7b1 by methylation of DNA
CG Penaloza, B Estevez, DM Han, M Norouzi, RA Lockshin, Z Zakeri
The FASEB Journal 28 (2), 966, 2014
722014
LIM kinase-1 selectively promotes glycoprotein Ib-IX–mediated TXA2 synthesis, platelet activation, and thrombosis
B Estevez, A Stojanovic-Terpo, MK Delaney, KA O’Brien, MC Berndt, ...
Blood, The Journal of the American Society of Hematology 121 (22), 4586-4594, 2013
442013
The interaction of Gα13 with integrin β1 mediates cell migration by dynamic regulation of RhoA
B Shen, B Estevez, Z Xu, B Kreutz, A Karginov, Y Bai, F Qian, U Norifumi, ...
Molecular biology of the cell 26 (20), 3658-3670, 2015
292015
The direct thrombin inhibitors dabigatran and lepirudin inhibit GPIbα-mediated platelet aggregation
K Trabold, S Makhoul, S Gambaryan, J van Ryn, U Walter, K Jurk
Thrombosis and haemostasis 119 (06), 916-929, 2019
232019
RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells
B Estevez, S Borst, D Jarocha, V Sudunagunta, M Gonzalez, J Garifallou, ...
Blood, The Journal of the American Society of Hematology 137 (19), 2662-2675, 2021
172021
RGS10 and RGS18 differentially limit platelet activation, promote platelet production, and prolong platelet survival
D DeHelian, S Gupta, J Wu, C Thorsheim, B Estevez, M Cooper, K Litts, ...
Blood, The Journal of the American Society of Hematology 136 (15), 1773-1782, 2020
152020
RUNX1-deficient human megakaryocytes demonstrate thrombopoietic and platelet half-life and functional defects
K Lee, HS Ahn, B Estevez, M Poncz
Blood 141 (3), 260-270, 2023
42023
Defective RAB31-mediated megakaryocytic early endosomal trafficking of VWF, EGFR, and M6PR in RUNX1 deficiency
G Jalagadugula, G Mao, LE Goldfinger, J Wurtzel, F Del Carpio-Cano, ...
Blood Advances 6 (17), 5100-5112, 2022
42022
Platelet factor 4 (PF4) enhances in vitro Neutrophil Extracellular Traps (NET) capture of coronaviruses: clinical and therapeutic implications
M Ishizuka, B Estevez, A Sarkar, MA Kowalska, L Rauova, M Poncz, ...
Research and Practice in Thrombosis and Haemostasis, 2021
22021
RUNX1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells: Mechanistic studies and drug correction
B Estevez, S Borst, D Jarocha, V Sudunagunta, M Gonzalez, J Garifallou, ...
bioRxiv, 2020.08. 23.260281, 2020
12020
A Platelet Glycoprotein Ib-IX-specific 14-3-3/Rac1/LIMK1 Signaling Pathway Promotes Thrombin-Induced Platelet Activation
B Estevez, K Delaney, A Stojanovic-Terpo, X Du
Arteriosclerosis, Thrombosis, and Vascular Biology 35 (suppl_1), A598-A598, 2015
12015
A signaling mechanism by which platelet glycoprotein Ib-IX promotes thrombin-induced platelet activation
B Estevez, MK Delaney, A Stojanovic-Terpo, X Du
Blood 124 (21), 2759, 2014
12014
RUNX1-deficient human megakaryocytes demonstrate thrombopoietic and platelet half-life and functional defects: Therapeutic implications
K Lee, HS Ahn, B Estevez, M Poncz
bioRxiv, 2022.09. 12.507354, 2022
2022
The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte …
B Estevez, S Borst, DJ Jarocha, V Sudunagunta, M Gonzalez, P Gao, ...
Blood 134, 220, 2019
2019
Signaling Mechanisms of the Glycoprotein Ib-IX-V Complex and Role of LIM kinase 1 in Platelet Activation
B Estevez
University of Illinois at Chicago, 2016
2016
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