Crystal structure of the human β2 adrenergic G-protein-coupled receptor SGF Rasmussen, HJ Choi, DM Rosenbaum, TS Kobilka, FS Thian, ... Nature 450 (7168), 383-387, 2007 | 2587 | 2007 |
Ultrahigh resolution drug design I: Details of interactions in human aldose reductase–inhibitor complex at 0.66 Å EI Howard, R Sanishvili, RE Cachau, A Mitschler, B Chevrier, P Barth, ... Proteins: Structure, Function, and Bioinformatics 55 (4), 792-804, 2004 | 358 | 2004 |
Structure of a HOIP/E2~ ubiquitin complex reveals RBR E3 ligase mechanism and regulation BC Lechtenberg, A Rajput, R Sanishvili, MK Dobaczewska, CF Ware, ... Nature 529 (7587), 546-550, 2016 | 181 | 2016 |
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 µm size X-ray synchrotron beam V Cherezov, MA Hanson, MT Griffith, MC Hilgart, R Sanishvili, ... Journal of The Royal Society Interface 6 (suppl_5), S587-S597, 2009 | 178 | 2009 |
Structure and photoinduced electron transfer in exceptionally stable synthetic DNA hairpins with stilbenediether linkers FD Lewis, X Liu, Y Wu, SE Miller, MR Wasielewski, RL Letsinger, ... Journal of the American Chemical Society 121 (42), 9905-9906, 1999 | 170 | 1999 |
X‐ray crystallographic analysis of the hydration of A‐and B‐form DNA at atomic resolution M Egli, V Tereshko, M Teplova, G Minasov, A Joachimiak, R Sanishvili, ... Biopolymers: Original Research on Biomolecules 48 (4), 234-252, 1998 | 163 | 1998 |
The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results G Rosenbaum, RW Alkire, G Evans, FJ Rotella, K Lazarski, RG Zhang, ... Journal of synchrotron radiation 13 (1), 30-45, 2006 | 161 | 2006 |
Taking MAD to the extreme: ultrafast protein structure determination MA Walsh, I Dementieva, G Evans, R Sanishvili, A Joachimiak Acta Crystallographica Section D: Biological Crystallography 55 (6), 1168-1173, 1999 | 148 | 1999 |
Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli R Sanishvili, AF Yakunin, RA Laskowski, T Skarina, E Evdokimova, ... Journal of Biological Chemistry 278 (28), 26039-26045, 2003 | 144 | 2003 |
In crystallo posttranslational modification within a MauG/pre–methylamine dehydrogenase complex LMR Jensen, R Sanishvili, VL Davidson, CM Wilmot Science 327 (5971), 1392-1394, 2010 | 138 | 2010 |
Radiation damage in protein crystals is reduced with a micron-sized X-ray beam R Sanishvili, DW Yoder, SB Pothineni, G Rosenbaum, S Xu, S Vogt, ... Proceedings of the National Academy of Sciences 108 (15), 6127-6132, 2011 | 121 | 2011 |
Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism JJ Barycki, LK O'Brien, JM Bratt, R Zhang, R Sanishvili, AW Strauss, ... Biochemistry 38 (18), 5786-5798, 1999 | 120 | 1999 |
Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2 CB Poor, SV Wegner, H Li, AC Dlouhy, JP Schuermann, R Sanishvili, ... Proceedings of the National Academy of Sciences 111 (11), 4043-4048, 2014 | 115 | 2014 |
In situ data collection and structure refinement from microcapillary protein crystallization MK Yadav, CJ Gerdts, R Sanishvili, WW Smith, LS Roach, RF Ismagilov, ... Journal of applied crystallography 38 (6), 900-905, 2005 | 112 | 2005 |
The low ionic strength crystal structure of horse cytochrome c at 2.1 Å resolution and comparison with its high ionic strength counterpart R Sanishvili, KW Volz, EM Westbrook, E Margoliash Structure 3 (7), 707-716, 1995 | 100 | 1995 |
Mini-beam collimator enables microcrystallography experiments on standard beamlines RF Fischetti, S Xu, DW Yoder, M Becker, V Nagarajan, R Sanishvili, ... Journal of synchrotron radiation 16 (2), 217-225, 2009 | 99 | 2009 |
MAD data collection–current trends MA Walsh, G Evans, R Sanishvili, I Dementieva, A Joachimiak Acta Crystallographica Section D: Biological Crystallography 55 (10), 1726-1732, 1999 | 96 | 1999 |
The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding M Teplova, V Tereshko, R Sanishvili, A Joachimiak, T Bushueva, ... Protein Science 9 (12), 2557-2566, 2000 | 94 | 2000 |
Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes H Robinson, YG Gao, R Sanishvili, A Joachimiak, AHJ Wang Nucleic acids research 28 (8), 1760-1766, 2000 | 89 | 2000 |
A 7 µm mini-beam improves diffraction data from small or imperfect crystals of macromolecules R Sanishvili, V Nagarajan, D Yoder, M Becker, S Xu, S Corcoran, DL Akey, ... Acta Crystallographica Section D: Biological Crystallography 64 (4), 425-435, 2008 | 85 | 2008 |