Nicholas Furnham
Nicholas Furnham
London School of Hygiene and Tropical Medicine
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CATH: comprehensive structural and functional annotations for genome sequences
I Sillitoe, TE Lewis, A Cuff, S Das, P Ashford, NL Dawson, N Furnham, ...
Nucleic acids research 43 (D1), D376-D381, 2015
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures
I Sillitoe, AL Cuff, BH Dessailly, NL Dawson, N Furnham, D Lee, JG Lees, ...
Nucleic acids research 41 (D1), D490-D498, 2013
Assembly and channel opening in a bacterial drug efflux machine
VN Bavro, Z Pietras, N Furnham, L Pérez-Cano, J Fernández-Recio, ...
Molecular cell 30 (1), 114, 2008
R., and Luisi, B.(2008)
VN Bavro, Z Pietras, N Furnham, L Pérez-Cano, P Fernández-Recio, ...
Mol. Cell 30, 114-121, 0
The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes
N Furnham, GL Holliday, TAP de Beer, JOB Jacobsen, WR Pearson, ...
Nucleic acids research 42 (D1), D485-D489, 2014
Extending CATH: increasing coverage of the protein structure universe and linking structure with function
AL Cuff, I Sillitoe, T Lewis, AB Clegg, R Rentzsch, N Furnham, ...
Nucleic acids research 39 (suppl 1), D420-D426, 2011
Is one solution good enough?
N Furnham, TL Blundell, MA DePristo, TC Terwilliger
Nature structural & molecular biology 13 (3), 184-185, 2006
The classification and evolution of enzyme function
SM Cuesta, SA Rahman, N Furnham, JM Thornton
Biophysical journal 109 (6), 1082-1086, 2015
Biophysical Review
SM Cuesta, SA Rahman, N Furnham, JM Thornton
EC-BLAST: a tool to automatically search and compare enzyme reactions
SA Rahman, SM Cuesta, N Furnham, GL Holliday, JM Thornton
Nature methods, 2014
Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies
N Furnham, I Sillitoe, GL Holliday, AL Cuff, RA Laskowski, CA Orengo, ...
PLoS computational biology 8 (3), e1002403, 2012
Structure of an Xrcc4–DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode
AS Doré, N Furnham, OR Davies, BL Sibanda, DY Chirgadze, ...
DNA repair 5 (3), 362-368, 2006
Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity
N Tyagi, EJ Farnell, CM Fitzsimmons, S Ryan, E Tukahebwa, RM Maizels, ...
PLoS Comput Biol 11 (10), e1004546, 2015
Missing in action: enzyme functional annotations in biological databases
N Furnham, JS Garavelli, R Apweiler, JM Thornton
Nature chemical biology 5 (8), 521-525, 2009
Structural basis for inhibition of homologous recombination by the RecX protein
S Ragone, JD Maman, N Furnham, L Pellegrini
The EMBO journal 27 (16), 2259-2269, 2008
Large-scale analysis exploring evolution of catalytic machineries and mechanisms in enzyme superfamilies
N Furnham, NL Dawson, SA Rahman, JM Thornton, CA Orengo
Journal of Molecular Biology, 2015
FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies
N Furnham, I Sillitoe, GL Holliday, AL Cuff, SA Rahman, RA Laskowski, ...
Nucleic acids research 40 (D1), D776-D782, 2012
Splice variants: a homology modeling approach
N Furnham, S Ruffle, C Southan
PROTEINS: Structure, Function, and Bioinformatics 54 (3), 596-608, 2003
Knowledge-based real-space explorations for low-resolution structure determination
N Furnham, AS Doré, DY Chirgadze, PIW de Bakker, MA DePristo, ...
Structure 14 (8), 1313-1320, 2006
Structure and mechanism of drug efflux machinery in Gram negative bacteria
Z Pietras, VN Bavro, N Furnham, M Pellegrini-Calace, EJ Milner-White, ...
Current drug targets 9 (9), 719-728, 2008
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