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Edward B Lee
Edward B Lee
Verified email at pennmedicine.upenn.edu - Homepage
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Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
106972021
Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis
J Brettschneider, K Del Tredici, JB Toledo, JL Robinson, DJ Irwin, ...
Annals of neurology 74 (1), 20-38, 2013
9902013
Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration
EB Lee, VMY Lee, JQ Trojanowski
Nature Reviews Neuroscience 13 (1), 38-50, 2012
7192012
Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ...
Nature medicine 26 (5), 769-780, 2020
6322020
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1268-1283. e6, 2018
5762018
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
M Neumann, LK Kwong, EB Lee, E Kremmer, A Flatley, Y Xu, MS Forman, ...
Acta neuropathologica 117, 137-149, 2009
5652009
Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated
JL Robinson, EB Lee, SX Xie, L Rennert, ER Suh, C Bredenberg, ...
Brain 141 (7), 2181-2193, 2018
5242018
Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model
B Zhang, A Maiti, S Shively, F Lakhani, G McDonald-Jones, J Bruce, ...
Proceedings of the National Academy of Sciences 102 (1), 227-231, 2005
4912005
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
LM Igaz, LK Kwong, EB Lee, A Chen-Plotkin, E Swanson, T Unger, ...
The Journal of clinical investigation 121 (2), 726-738, 2011
4702011
Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
DJ Irwin, M Grossman, D Weintraub, HI Hurtig, JE Duda, SX Xie, EB Lee, ...
The Lancet Neurology 16 (1), 55-65, 2017
4442017
Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
GG Kovacs, I Ferrer, LT Grinberg, I Alafuzoff, J Attems, H Budka, ...
Acta neuropathologica 131, 87-102, 2016
4322016
Targeting amyloid-β peptide (Aβ) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Aβ precursor protein (APP …
EB Lee, LZ Leng, B Zhang, L Kwong, JQ Trojanowski, T Abel, VMY Lee
Journal of Biological Chemistry 281 (7), 4292-4299, 2006
3862006
C9orf72 BAC transgenic mice display typical pathologic features of ALS/FTD
JG O’Rourke, L Bogdanik, A Muhammad, TF Gendron, KJ Kim, A Austin, ...
Neuron 88 (5), 892-901, 2015
3242015
SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network
J Hu, X Li, K Coleman, A Schroeder, N Ma, DJ Irwin, EB Lee, ...
Nature methods 18 (11), 1342-1351, 2021
3142021
Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias
M Yarchoan, SX Xie, MA Kling, JB Toledo, DA Wolk, EB Lee, ...
Brain 135 (12), 3749-3756, 2012
3062012
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited
O Lazarov, GA Morfini, EB Lee, MH Farah, A Szodorai, SR DeBoer, ...
Journal of Neuroscience 25 (9), 2386-2395, 2005
2702005
Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine
DJ Irwin, NJ Cairns, M Grossman, CT McMillan, EB Lee, VM Van Deerlin, ...
Acta neuropathologica 129, 469-491, 2015
2632015
Distribution patterns of tau pathology in progressive supranuclear palsy
GG Kovacs, MJ Lukic, DJ Irwin, T Arzberger, G Respondek, EB Lee, ...
Acta neuropathologica 140, 99-119, 2020
2512020
TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord
J Brettschneider, K Arai, K Del Tredici, JB Toledo, JL Robinson, EB Lee, ...
Acta neuropathologica 128, 423-437, 2014
2512014
Olfactory epithelium amyloid‐β and paired helical filament‐tau pathology in Alzheimer disease
SE Arnold, EB Lee, PJ Moberg, L Stutzbach, H Kazi, LY Han, VMY Lee, ...
Annals of neurology 67 (4), 462-469, 2010
2222010
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