| Drug bioavailability enhancing agents of natural origin (bioenhancers) that modulate drug membrane permeation and pre-systemic metabolism B Peterson, M Weyers, JH Steenekamp, JD Steyn, C Gouws, JH Hamman Pharmaceutics 11 (1), 33, 2019 | 91 | 2019 |
| Assessing the DNA methylation status of single cells with the comet assay JF Wentzel, C Gouws, C Huysamen, E Dyk, G Koekemoer, PJ Pretorius Analytical biochemistry 400 (2), 190-194, 2010 | 83 | 2010 |
| Herbal hepatotoxicity: current status, examples, and challenges C Calitz, L du Plessis, C Gouws, D Steyn, J Steenekamp, C Muller, ... Expert opinion on drug metabolism & toxicology 11 (10), 1551-1565, 2015 | 58 | 2015 |
| Efflux as a mechanism of antimicrobial drug resistance in clinical relevant microorganisms: the role of efflux inhibitors C Willers, JF Wentzel, LH du Plessis, C Gouws, JH Hamman Expert opinion on therapeutic targets 21 (1), 23-36, 2017 | 51 | 2017 |
| Combination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux C Gouws, D Steyn, L Du Plessis, J Steenekamp, JH Hamman Expert Opinion on Drug Metabolism & Toxicology 8 (8), 973-984, 2012 | 44 | 2012 |
| What are the dangers of drug interactions with herbal medicines? C Gouws, JH Hamman Expert opinion on drug metabolism & toxicology 16 (3), 165-167, 2020 | 36 | 2020 |
| Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspective C Calitz, JH Hamman, SJ Fey, K Wrzesinski, C Gouws Toxicology mechanisms and methods 28 (5), 369-385, 2018 | 31 | 2018 |
| Characterization of an alginate encapsulated LS180 spheroid model for anti-colorectal cancer compound screening T Smit, C Calitz, C Willers, H Svitina, J Hamman, SJ Fey, C Gouws, ... ACS Medicinal Chemistry Letters 11 (5), 1014-1021, 2020 | 20 | 2020 |
| Cell-free DNA in a three-dimensional spheroid cell culture model: A preliminary study J Aucamp, C Calitz, AJ Bronkhorst, K Wrzesinski, S Hamman, C Gouws, ... The international journal of biochemistry & cell biology 89, 182-192, 2017 | 19 | 2017 |
| Aloe vera gel and whole leaf extract: functional and versatile excipients for drug delivery? A Laux, C Gouws, JH Hamman Expert opinion on drug delivery 16 (12), 1283-1285, 2019 | 17 | 2019 |
| Isolation and in vitro permeation of phenylpropylamino alkaloids from Khat (Catha edulis) across oral and intestinal mucosal tissues M Atlabachew, S Combrinck, AM Viljoen, JH Hamman, C Gouws Journal of Ethnopharmacology 194, 307-315, 2016 | 17 | 2016 |
| Treatment of Skin Disorders with Aloe Materials H Svitina, R Swanepoel, J Rossouw, H Netshimbupfe, C Gouws, ... Current pharmaceutical design 25 (20), 2208-2240, 2019 | 15 | 2019 |
| Impact of traditional African medicine on drug metabolism and transport C Calitz, JH Steenekamp, JD Steyn, C Gouws, JM Viljoen, JH Hamman Expert Opin. Drug Metab. Toxicol. 10 (7), 991-1003, 2014 | 15 | 2014 |
| O 6-methylguanine-DNA methyltransferase (MGMT): Can function explain a suicidal mechanism? C Gouws, PJ Pretorius Medical hypotheses 77 (5), 857-860, 2011 | 15 | 2011 |
| Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short-term exposure to two-dimensional and three-dimensional spheroid cell … C Calitz, JH Hamman, AM Viljoen, SJ Fey, K Wrzesinski, C Gouws Toxicology mechanisms and methods 28 (9), 641-652, 2018 | 14 | 2018 |
| Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products C Calitz, C Gouws, J Viljoen, J Steenekamp, L Wiesner, E Abay, ... Molecules 20 (12), 22113-22127, 2015 | 13 | 2015 |
| Anticancer Potential of Sutherlandia frutescens and Xysmalobium undulatum in LS180 Colorectal Cancer Mini-Tumors C Gouws, T Smit, C Willers, H Svitina, C Calitz, K Wrzesinski Molecules 26 (3), 605, 2021 | 12 | 2021 |
| A sub-chronic Xysmalobium undulatum hepatotoxicity investigation in HepG2/C3A spheroid cultures compared to an in vivo model C Calitz, JH Hamman, SJ Fey, AM Viljoen, C Gouws, K Wrzesinski Journal of ethnopharmacology 239, 111897, 2019 | 12 | 2019 |
| Molecular mechanisms and associated cell signalling pathways underlying the anticancer properties of phytochemical compounds from Aloe species H Svitina, JH Hamman, C Gouws Experimental and Therapeutic Medicine 22 (2), 1-23, 2021 | 11 | 2021 |
| Recent developments in our understanding of the implications of traditional African medicine on drug metabolism C Gouws, JH Hamman Expert opinion on drug metabolism & toxicology 14 (2), 161-168, 2018 | 11 | 2018 |
