Rithwik Ramachandran
Rithwik Ramachandran
Підтверджена електронна адреса в uwo.ca - Домашня сторінка
The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 176, S21-S141, 2019
Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more
R Ramachandran, MD Hollenberg
British journal of pharmacology 153 (S1), S263-S282, 2008
Structure, function and pathophysiology of protease activated receptors
MN Adams, R Ramachandran, MK Yau, JY Suen, DP Fairlie, ...
Pharmacology & therapeutics 130 (3), 248-282, 2011
Targeting proteinase-activated receptors: therapeutic potential and challenges
R Ramachandran, F Noorbakhsh, K DeFea, MD Hollenberg
Nature reviews Drug discovery 11 (1), 69-86, 2012
The concise guide to pharmacology 2017/18: overview
SPH Alexander, E Kelly, NV Marrion, JA Peters, E Faccenda, SD Harding, ...
British journal of pharmacology 174, S1-S16, 2017
The concise guide to PHARMACOLOGY 2013/14: overview
SPH Alexander, HE Benson, E Faccenda, AJ Pawson, JL Sharman, ...
British journal of pharmacology 170 (8), 1449-1458, 2013
Biased signalling and proteinase‐activated receptors (PAR s): targeting inflammatory disease
MD Hollenberg, K Mihara, D Polley, JY Suen, A Han, DP Fairlie, ...
British journal of pharmacology 171 (5), 1180-1194, 2014
Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2)
R Ramachandran, K Mihara, H Chung, B Renaux, CS Lau, DA Muruve, ...
Journal of Biological Chemistry 286 (28), 24638-24648, 2011
TRPM8 activation attenuates inflammatory responses in mouse models of colitis
R Ramachandran, E Hyun, L Zhao, TK Lapointe, K Chapman, CL Hirota, ...
Proceedings of the National Academy of Sciences 110 (18), 7476-7481, 2013
Neutrophil elastase and proteinase-3 trigger G protein-biased signaling through proteinase-activated receptor-1 (PAR1)
K Mihara, R Ramachandran, B Renaux, M Saifeddine, MD Hollenberg
Journal of Biological Chemistry 288 (46), 32979-32990, 2013
Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways
R Ramachandran, K Mihara, M Mathur, MD Rochdi, M Bouvier, K DeFea, ...
Molecular pharmacology 76 (4), 791-801, 2009
MicroRNA profiling reveals new aspects of HIV neurodegeneration: caspase‐6 regulates astrocyte survival
F Noorbakhsh, R Ramachandran, N Barsby, KK Ellestad, A LeBlanc, ...
The FASEB Journal 24 (6), 1799-1812, 2010
The active Zot domain (aa 288–293) increases ZO‐1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO‐1 and its binding partners, and induces tight …
SE Goldblum, U Rai, A Tripathi, M Thakar, L De Leo, N Di Toro, T Not, ...
The FASEB journal 25 (1), 144-158, 2011
Proteinase-activated receptor-2 transactivation of epidermal growth factor receptor and transforming growth factor-β receptor signaling pathways contributes to renal fibrosis
H Chung, R Ramachandran, MD Hollenberg, DA Muruve
Journal of Biological Chemistry 288 (52), 37319-37331, 2013
Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer
MD Hollenberg, K Oikonomopoulou, KK Hansen, M Saifeddine, ...
Walter de Gruyter 389 (6), 643-651, 2008
Thrombin-mediated direct activation of proteinase-activated receptor-2: another target for thrombin signaling
K Mihara, R Ramachandran, M Saifeddine, KK Hansen, B Renaux, ...
Molecular pharmacology 89 (5), 606-614, 2016
Activities enjoyed by patients with dementia together with their spouses and psychological morbidity in carers
R Searson, AM Hendry, R Ramachandran, A Burns, N Purandare
Aging and Mental Health 12 (2), 276-282, 2008
Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts
LR Sadofsky, R Ramachandran, C Crow, M Cowen, SJ Compton, ...
Experimental lung research 38 (2), 75-81, 2012
Proteinases, their extracellular targets, and inflammatory signaling
R Ramachandran, C Altier, K Oikonomopoulou, MD Hollenberg
Pharmacological reviews 68 (4), 1110-1142, 2016
Mechanisms behind the anti-inflammatory actions of insulin
E Hyun, R Ramachandran, MD Hollenberg, N Vergnolle
Critical Reviews™ in Immunology 31 (4), 2011
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Статті 1–20