Role of the extremolytes ectoine and hydroxyectoine as stress protectants and nutrients: genetics, phylogenomics, biochemistry, and structural analysis L Czech, L Hermann, N Stöveken, AA Richter, A Höppner, SHJ Smits, ... Genes 9 (4), 177, 2018 | 217 | 2018 |
Strangers in the archaeal world: osmostress‐responsive biosynthesis of ectoine and hydroxyectoine by the marine thaumarchaeon Nitrosopumilus maritimus N Widderich, L Czech, FJ Elling, M Könneke, N Stöveken, M Pittelkow, ... Environmental microbiology 18 (4), 1227-1248, 2016 | 72 | 2016 |
Biosynthesis of the stress-protectant and chemical chaperon ectoine: biochemistry of the transaminase EctB AA Richter, CN Mais, L Czech, K Geyer, A Hoeppner, SHJ Smits, TJ Erb, ... Frontiers in Microbiology 10, 2019 | 58 | 2019 |
Tinkering with osmotically controlled transcription allows enhanced production and excretion of ectoine and hydroxyectoine from a microbial cell factory L Czech, S Poehl, P Hub, N Stöveken, E Bremer Applied and Environmental Microbiology 84 (2), e01772-17, 2018 | 39 | 2018 |
Illuminating the catalytic core of ectoine synthase through structural and biochemical analysis L Czech, A Höppner, S Kobus, A Seubert, R Riclea, JS Dickschat, ... Scientific Reports 9 (1), 364, 2019 | 34 | 2019 |
The ups and downs of ectoine: structural enzymology of a major microbial stress protectant and versatile nutrient L Hermann, CN Mais, L Czech, SHJ Smits, G Bange, E Bremer Biological chemistry 401 (12), 1443-1468, 2020 | 32 | 2020 |
EctD-mediated biotransformation of the chemical chaperone ectoine into hydroxyectoine and its mechanosensitive channel-independent excretion L Czech, N Stöveken, E Bremer Microbial Cell Factories 15, 1-16, 2016 | 28 | 2016 |
With a pinch of extra salt—Did predatory protists steal genes from their food? L Czech, E Bremer PLoS biology 16 (2), e2005163, 2018 | 21 | 2018 |
Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase–deacetylase complex CN Mais, L Hermann, F Altegoer, A Seubert, AA Richter, I Wernersbach, ... Journal of Biological Chemistry 295 (27), 9087-9104, 2020 | 17 | 2020 |
The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine AA Richter, S Kobus, L Czech, A Hoeppner, J Zarzycki, TJ Erb, ... Journal of Biological Chemistry 295 (9), 2822-2838, 2020 | 17 | 2020 |
Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p) ppGpp L Czech, CN Mais, H Kratzat, P Sarmah, P Giammarinaro, SA Freibert, ... Nature communications 13 (1), 1069, 2022 | 16 | 2022 |
Exploiting substrate promiscuity of ectoine hydroxylase for regio-and stereoselective modification of homoectoine L Czech, S Wilcken, O Czech, U Linne, J Brauner, SHJ Smits, EA Galinski, ... Frontiers in Microbiology 10, 2745, 2019 | 13 | 2019 |
How to save a bacterial ribosome in times of stress V Zegarra, P Bedrunka, G Bange, L Czech Seminars in Cell & Developmental Biology 136, 3-12, 2023 | 10 | 2023 |
Structural and functional characterization of MrpR, the master repressor of the Bacillus subtilis prophage SPβ K Kohm, E Jalomo-Khayrova, A Krüger, S Basu, W Steinchen, G Bange, ... Nucleic Acids Research 51 (17), 9452-9474, 2023 | 5 | 2023 |
E. coli Toxin YjjJ (HipH) Is a Ser/Thr Protein Kinase That Impacts Cell Division, Carbon Metabolism, and Ribosome Assembly FL Gratani, T Englert, P Nashier, P Sass, L Czech, N Neumann, S Doello, ... Msystems 8 (1), e01043-22, 2023 | 5 | 2023 |
Biosynthesis of the stress-protectant and chemical chaperon ectoine: biochemistry of the transaminase EctB. Front Microbiol 10: 2811 AA Richter, CN Mais, L Czech, K Geyer, A Hoeppner, SHJ Smits, TJ Erb, ... | 5 | 2019 |
Die Leiden der jungen Wissenschaftler A Lang, L Czech, A Probst BIOspektrum 26, 572-576, 2020 | 2 | 2020 |
Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate‐Containing Natural Products in Diverse Bacteria YM Shi, JJ Crames, L Czech, KAJ Bozhüyük, YN Shi, M Hirschmann, ... Angewandte Chemie International Edition 61 (51), e202206106, 2022 | 1 | 2022 |
Guilty by association: Importers, exporters and MscS‐type mechanosensitive channels encoded in biosynthetic gene clusters for the stress‐protectant ectoine L Czech, C Gertzen, SHJ Smits, E Bremer Environmental Microbiology 24 (11), 5306-5331, 2022 | 1 | 2022 |
Structural and functional analysis of YopR and identification of an additional key component of the SPβ phage lysis-lysogeny management system K Kohm, E Jalomo-Khayrova, S Basu, W Steinchen, G Bange, R Hertel, ... bioRxiv, https://www.biorxiv.org/content/10.1101/, 2022 | 1 | 2022 |