Adenosine A2A receptors play a role in the pathogenesis of hepatic cirrhosis ESL Chan, MC Montesinos, P Fernandez, A Desai, DL Delano, H Yee, ... British journal of pharmacology 148 (8), 1144-1155, 2006 | 281 | 2006 |
Anti-inflammatory actions of the heme oxygenase-1 pathway MJ Alcaraz, P Fernandez, MI Guillen Current pharmaceutical design 9 (30), 2541-2551, 2003 | 280 | 2003 |
Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP‐1 monocyte/macrophages AB Reiss, SE Carsons, K Anwar, S Rao, SD Edelman, H Zhang, ... Arthritis & Rheumatism 58 (12), 3675-3683, 2008 | 212 | 2008 |
The antiinflammatory mechanism of methotrexate depends on extracellular conversion of adenine nucleotides to adenosine by ecto‐5′‐nucleotidase: Findings in a study of ecto‐5 … MC Montesinos, M Takedachi, LF Thompson, TF Wilder, P Fernández, ... Arthritis & Rheumatism 56 (5), 1440-1445, 2007 | 175 | 2007 |
Ecto-5′-nucleotidase (CD73)-mediated extracellular adenosine production plays a critical role in hepatic fibrosis Z Peng, P Fernandez, T Wilder, H Yee, L Chiriboga, ESL Chan, ... The FASEB Journal 22 (7), 2263-2272, 2008 | 157 | 2008 |
Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma ESL Chan, P Fernandez, AA Merchant, MC Montesinos, S Trzaska, ... Arthritis & Rheumatism 54 (8), 2632-2642, 2006 | 155 | 2006 |
Control of cell proliferation in atherosclerosis: insights from animal models and human studies JJ Fuster, P Fernández, H González-Navarro, C Silvestre, YNA Nabah, ... Cardiovascular research 86 (2), 254-264, 2010 | 143 | 2010 |
Expression of heme oxygenase-1 and regulation by cytokines in human osteoarthritic chondrocytes P Fernández, MI Guillén, F Gomar, MJ Alcaraz Biochemical pharmacology 66 (10), 2049-2052, 2003 | 74 | 2003 |
Transformation Resistance in a Premature Aging Disorder Identifies a Tumor-Protective Function of BRD4 P Fernandez, P Scaffidi, E Markert, JH Lee, S Rane, T Misteli Cell reports 9 (1), 248-260, 2014 | 72 | 2014 |
Embryological-Origin–Dependent Differences in Homeobox Expression in Adult AortaSignificance: Role in Regional Phenotypic Variability and Regulation of NF-κB Activity L Trigueros-Motos, JM González-Granado, C Cheung, P Fernández, ... Arteriosclerosis, thrombosis, and vascular biology 33 (6), 1248-1256, 2013 | 69* | 2013 |
Pharmacological Blockade of A 2A Receptors Prevents Dermal Fibrosis in a Model of Elevated Tissue Adenosine P Fernández, S Trzaska, T Wilder, L Chiriboga, MR Blackburn, ... The American journal of pathology 172 (6), 1675-1682, 2008 | 67 | 2008 |
Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3 M Perez-Aso, P Fernandez, A Mediero, ES Chan, BN Cronstein The FASEB Journal 28 (2), 802-812, 2014 | 66 | 2014 |
Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis P Fernández, M Perez-Aso, G Smith, T Wilder, S Trzaska, L Chiriboga, ... The American journal of pathology 183 (6), 1740-1746, 2013 | 56 | 2013 |
Adenosine A2A receptor blockade or deletion diminishes fibrocyte accumulation in the skin in a murine model of scleroderma, bleomycin-induced fibrosis M Katebi, P Fernandez, ESL Chan, BN Cronstein Inflammation 31 (5), 299-303, 2008 | 53 | 2008 |
Adenosine A 2A receptors promote collagen production by a Fli1-and CTGF-mediated mechanism ESL Chan, H Liu, P Fernandez, A Luna, M Perez-Aso, AM Bujor, ... Arthritis research & therapy 15 (3), R58, 2013 | 51 | 2013 |
Chondrocyte hypertrophy and apoptosis induced by GROα require three‐dimensional interaction with the extracellular matrix and a co‐receptor role of chondroitin sulfate and are … E Olivotto, R Vitellozzi, P Fernandez, E Falcieri, M Battistelli, S Burattini, ... Journal of cellular physiology 210 (2), 417-427, 2007 | 50 | 2007 |
Effect of cyclooxygenase inhibition on cholesterol efflux proteins and atheromatous foam cell transformation in THP-1 human macrophages: a possible mechanism for increased … ESL Chan, H Zhang, P Fernandez, SD Edelman, MH Pillinger, L Ragolia, ... Arthritis research & therapy 9 (1), R4, 2007 | 40 | 2007 |
Genetically based resistance to the antiinflammatory effects of methotrexate in the air‐pouch model of acute inflammation DL Delano, MC Montesinos, A Desai, T Wilder, P Fernandez, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2005 | 39 | 2005 |
Adenosine in inflammatory joint diseases ESL Chan, P Fernandez, BN Cronstein Purinergic signalling 3 (1-2), 145-152, 2007 | 33 | 2007 |
A novel cyclo-oxygenase-2 inhibitor modulates catabolic and antiinflammatory mediators in osteoarthritis P Fernández, MI Guillén, F Gomar, E Aller, P Molina, MJ Alcaraz Biochemical pharmacology 68 (3), 417-421, 2004 | 25 | 2004 |