Gosia Trynka
Gosia Trynka
Group leader
Підтверджена електронна адреса в sanger.ac.uk - Домашня сторінка
Назва
Посилання
Посилання
Рік
Genetics of rheumatoid arthritis contributes to biology and drug discovery
Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ...
Nature 506 (7488), 376-381, 2014
13152014
Multiple common variants for celiac disease influencing immune gene expression
PCA Dubois, G Trynka, L Franke, KA Hunt, J Romanos, A Curtotti, ...
Nature genetics 42 (4), 295, 2010
8672010
Partitioning heritability by functional annotation using genome-wide association summary statistics
HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ...
Nature genetics 47 (11), 1228, 2015
7932015
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
LC Tsoi, SL Spain, J Knight, E Ellinghaus, PE Stuart, F Capon, J Ding, ...
Nature genetics 44 (12), 1341, 2012
6922012
Newly identified genetic risk variants for celiac disease related to the immune response
KA Hunt, A Zhernakova, G Turner, GAR Heap, L Franke, M Bruinenberg, ...
Nature genetics 40 (4), 395, 2008
6822008
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
G Trynka, KA Hunt, NA Bockett, J Romanos, V Mistry, A Szperl, SF Bakker, ...
Nature genetics 43 (12), 1193-1201, 2011
6482011
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ...
Nature genetics 44 (12), 1336, 2012
5022012
Chromatin marks identify critical cell types for fine mapping complex trait variants
G Trynka, C Sandor, B Han, H Xu, BE Stranger, XS Liu, S Raychaudhuri
Nature genetics 45 (2), 124-130, 2013
4342013
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ...
The American Journal of Human Genetics 95 (5), 535-552, 2014
3982014
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
EA Stahl, D Wegmann, G Trynka, J Gutierrez-Achury, R Do, BF Voight, ...
Nature genetics 44 (5), 483, 2012
3762012
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA
RSN Fehrmann, RC Jansen, JH Veldink, HJ Westra, D Arends, ...
PLoS genetics 7 (8), 2011
3382011
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci
A Zhernakova, EA Stahl, G Trynka, S Raychaudhuri, E Festen, L Franke, ...
Annals of the Rheumatic Diseases 70 (Suppl 2), A21-A21, 2011
3332011
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP
A Zhernakova, EM Festen, L Franke, G Trynka, CC van Diemen, ...
The American Journal of Human Genetics 82 (5), 1202-1210, 2008
2412008
Fine-mapping inflammatory bowel disease loci to single-variant resolution
H Huang, M Fang, L Jostins, MU Mirkov, G Boucher, CA Anderson, ...
Nature 547 (7662), 173-178, 2017
1932017
Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-κB signalling
G Trynka, A Zhernakova, J Romanos, L Franke, KA Hunt, G Turner, ...
Gut 58 (8), 1078-1083, 2009
1912009
ImmunoChip study implicates antigen presentation to T cells in narcolepsy
J Faraco, L Lin, BR Kornum, EE Kenny, G Trynka, M Einen, TJ Rico, ...
PLoS genetics 9 (2), 2013
1812013
A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease
EAM Festen, P Goyette, T Green, G Boucher, C Beauchamp, G Trynka, ...
PLoS genetics 7 (1), 2011
1722011
Analysis of HLA and non-HLA alleles can identify individuals at high risk for celiac disease
J Romanos, CC Van Diemen, IM Nolte, G Trynka, A Zhernakova, J Fu, ...
Gastroenterology 137 (3), 834-840. e3, 2009
1602009
Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection
A Zhernakova, CC Elbers, B Ferwerda, J Romanos, G Trynka, PC Dubois, ...
The American Journal of Human Genetics 86 (6), 970-977, 2010
1562010
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, ...
Nature genetics 49 (3), 416, 2017
1542017
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