| Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease X Pan, Y Zhu, N Lin, J Zhang, Q Ye, H Huang, X Chen Molecular neurodegeneration 6, 1-18, 2011 | 312 | 2011 |
| Ginsenoside Rg1 attenuates amyloid-β content, regulates PKA/CREB activity, and improves cognitive performance in SAMP8 mice YQ Shi, TW Huang, LM Chen, XD Pan, J Zhang, YG Zhu, XC Chen Journal of Alzheimer's Disease 19 (3), 977-989, 2010 | 135 | 2010 |
| Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function Y Lai, P Lin, M Chen, Y Zhang, J Chen, M Zheng, J Liu, H Du, R Chen, ... Redox Biology 34, 101503, 2020 | 115 | 2020 |
| Tripchlorolide protects neuronal cells from microglia‐mediated β‐amyloid neurotoxicity through inhibiting NF‐κB and JNK signaling XD Pan, XC Chen, YG Zhu, LM Chen, J Zhang, TW Huang, QY Ye, ... Glia 57 (11), 1227-1238, 2009 | 107 | 2009 |
| APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice D Liu, X Pan, J Zhang, H Shen, NC Collins, AM Cole, KP Koster, ... Molecular neurodegeneration 10, 1-17, 2015 | 100 | 2015 |
| Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells L Chen, Z Lin, Y Zhu, N Lin, J Zhang, X Pan, X Chen European journal of pharmacology 675 (1-3), 15-21, 2012 | 84 | 2012 |
| Amyloid β protein aggravates neuronal senescence and cognitive deficits in 5XFAD mouse model of Alzheimer’s disease Z Wei, XC Chen, Y Song, XD Pan, XM Dai, J Zhang, XL Cui, XL Wu, ... Chinese medical journal 129 (15), 1835-1844, 2016 | 74 | 2016 |
| Clinic, neuropathology and molecular genetics of frontotemporal dementia: a mini-review X Pan, X Chen Translational neurodegeneration 2, 1-9, 2013 | 72 | 2013 |
| GLP-1 improves the supportive ability of astrocytes to neurons by promoting aerobic glycolysis in Alzheimer's disease J Zheng, Y Xie, L Ren, L Qi, L Wu, X Pan, J Zhou, Z Chen, L Liu Molecular metabolism 47, 101180, 2021 | 71 | 2021 |
| Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia X Pan, X Chen, Y Zhu, J Zhang, T Huang, L Chen, Q Ye, H Huang Biochemical pharmacology 76 (3), 362-372, 2008 | 63 | 2008 |
| LRRK2 modulates microglial activity through regulation of chemokine (C–X3–C) receptor 1–mediated signalling pathways B Ma, L Xu, X Pan, L Sun, J Ding, C Xie, VE Koliatsos, H Cai Human molecular genetics 25 (16), 3515-3523, 2016 | 60 | 2016 |
| Ginsenoside Rb1 selectively inhibits the activity of L-type voltage-gated calcium channels in cultured rat hippocampal neurons Z Lin, L Chen, J Zhang, X Pan, Y Zhu, Q Ye, H Huang, X Chen Acta Pharmacologica Sinica 33 (4), 438-444, 2012 | 58 | 2012 |
| Abnormal resting‐state functional connectivity in posterior cingulate cortex of Parkinson's disease with mild cognitive impairment and dementia ZW Zhan, LZ Lin, EH Yu, JW Xin, L Lin, HL Lin, QY Ye, XC Chen, XD Pan CNS neuroscience & therapeutics 24 (10), 897-905, 2018 | 56 | 2018 |
| Exenatide alleviates mitochondrial dysfunction and cognitive impairment in the 5× FAD mouse model of Alzheimer’s disease J An, Y Zhou, M Zhang, Y Xie, S Ke, L Liu, X Pan, Z Chen Behavioural brain research 370, 111932, 2019 | 51 | 2019 |
| Tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and NMDA receptor dysfunction in SAMP8 mice N Lin, X Pan, A Chen, Y Zhu, M Wu, J Zhang, X Chen Behavioural brain research 258, 8-18, 2014 | 50 | 2014 |
| Tripchlorolide improves cognitive deficits by reducing amyloid β and upregulating synapse‐related proteins in a transgenic model of Alzheimer's disease Y Zeng, J Zhang, Y Zhu, J Zhang, H Shen, J Lu, X Pan, N Lin, X Dai, ... Journal of neurochemistry 133 (1), 38-52, 2015 | 48 | 2015 |
| Netrin-1 promotes synaptic formation and axonal regeneration via JNK1/c-Jun pathway after the middle cerebral artery occlusion M Zheng, R Chen, H Chen, Y Zhang, J Chen, P Lin, Q Lan, Q Yuan, Y Lai, ... Frontiers in Cellular Neuroscience 12, 13, 2018 | 40 | 2018 |
| Aging-related changes in RP3V kisspeptin neurons predate the reduced activation of GnRH neurons during the early reproductive decline in female mice J Zhang, L Yang, N Lin, X Pan, Y Zhu, X Chen Neurobiology of aging 35 (3), 655-668, 2014 | 39 | 2014 |
| Tripchlorolide attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a/APP695 cells N Lin, L Chen, X Pan, Y Zhu, J Zhang, Y Shi, X Chen Molecular neurobiology 53, 6397-6406, 2016 | 32 | 2016 |
| Exendin-4 protects Aβ (1-42) oligomer-induced PC12 cell apoptosis C Qiu, YP Wang, XD Pan, XY Liu, Z Chen, LB Liu American Journal of Translational Research 8 (8), 3540, 2016 | 29 | 2016 |
Huaibin CaiSenior Investigator, National Institute on Aging, National Institutes of HealthVerified email at mail.nih.gov
