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| The E3-11.6-KDa Adenovirus Death Protein (ADP) Is Required for Efficient Cell Death: Characterization of Cells Infected WithadpMutants ANNE TOLLEFSON, JANS RYERSE, A SCARIA, TW HERMISTON, ... Virology 220 (1), 152-162, 1996 | 312 | 1996 |
| Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains. D Barr, J Tubb, D Ferguson, A Scaria, A Lieber, C Wilson, J Perkins, ... Gene therapy 2 (2), 151-155, 1995 | 286 | 1995 |
| CRISPR/Cas9-mediated genome editing as a therapeutic approach for Leber congenital amaurosis 10 GX Ruan, E Barry, D Yu, M Lukason, SH Cheng, A Scaria Molecular therapy 25 (2), 331-341, 2017 | 276 | 2017 |
| Intravitreous injection of AAV2-sFLT01 in patients with advanced neovascular age-related macular degeneration: a phase 1, open-label trial JS Heier, S Kherani, S Desai, P Dugel, S Kaushal, SH Cheng, ... The Lancet 390 (10089), 50-61, 2017 | 216 | 2017 |
| Preclinical safety evaluation of AAV2-sFLT01—a gene therapy for age-related macular degeneration TK MacLachlan, M Lukason, M Collins, R Munger, E Isenberger, ... Molecular Therapy 19 (2), 326-334, 2011 | 193 | 2011 |
| Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization P Pechan, H Rubin, M Lukason, J Ardinger, E DuFresne, WW Hauswirth, ... Gene therapy 16 (1), 10-16, 2009 | 168 | 2009 |
| Analytical ultracentrifugation as an approach to characterize recombinant adeno-associated viral vectors B Burnham, S Nass, E Kong, ME Mattingly, D Woodcock, A Song, ... Human gene therapy methods 26 (6), 228-242, 2015 | 153 | 2015 |
| Universal method for the purification of recombinant AAV vectors of differing serotypes SA Nass, MA Mattingly, DA Woodcock, BL Burnham, JA Ardinger, ... Molecular Therapy Methods & Clinical Development 9, 33-46, 2018 | 127 | 2018 |
| The 11,600-MW protein encoded by region E3 of adenovirus is expressed early but is greatly amplified at late stages of infection AE Tollefson, A Scaria, SK Saha, WS Wold Journal of virology 66 (6), 3633-3642, 1992 | 124 | 1992 |
| Translational Fidelity of Intrathecal Delivery of Self-Complementary AAV9–Survival Motor Neuron 1 for Spinal Muscular Atrophy MA Passini, J Bu, AM Richards, CM Treleaven, JA Sullivan, CR O'Riordan, ... Human gene therapy 25 (7), 619-630, 2014 | 111 | 2014 |
| Antibody to CD40 ligand inhibits both humoral and cellular immune responses to adenoviral vectors and facilitates repeated administration to mouse airway A Scaria, JA St George, RJ Gregory, RJ Noelle, SC Wadsworth, AE Smith, ... Gene Therapy 4 (6), 611-617, 1997 | 109 | 1997 |
| Inhibition of choroidal neovascularization in a nonhuman primate model by intravitreal administration of an AAV2 vector expressing a novel anti-VEGF molecule M Lukason, E DuFresne, H Rubin, P Pechan, Q Li, I Kim, S Kiss, C Flaxel, ... Molecular Therapy 19 (2), 260-265, 2011 | 108 | 2011 |
| Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation G Simon, M Parker, V Ramiya, C Wasserfall, Y Huang, D Bresson, ... Diabetes 57 (2), 405-414, 2008 | 88 | 2008 |
| Demonstration of feasibility of in vivo gene therapy for Gaucher disease using a chemically induced mouse model J Marshall, KA McEachern, JAC Kyros, JB Nietupski, TL Budzinski, ... Molecular Therapy 6 (2), 179-189, 2002 | 73 | 2002 |
| Adenoviral vectors capable of facilitating increased persistence of transgene expression A Scaria, RJ Gregory, SC Wadsworth US Patent 6,020,191, 2000 | 72 | 2000 |
| Delivery of CFTR by adenoviral vector to cystic fibrosis mouse lung in a model of chronic Pseudomonas aeruginosa lung infection AM Van Heeckeren, A Scaria, MD Schluchter, TW Ferkol, S Wadsworth, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 286 (4 …, 2004 | 70 | 2004 |
| The E3-11.6 K protein of adenovirus is an Asn-glycosylated integral membrane protein that localizes to the nuclear membrane A Scaria, AE Tollefson, SK Saha, WSM Wold Virology 191 (2), 743-753, 1992 | 61 | 1992 |
| Characterization of in vitro antimurine thymocyte globulin–induced regulatory T cells that inhibit graft-versus-host disease in vivo MC Ruzek, JS Waire, D Hopkins, G LaCorcia, J Sullivan, BL Roberts, ... Blood, The Journal of the American Society of Hematology 111 (3), 1726-1734, 2008 | 52 | 2008 |
| Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration D Ardeljan, Y Wang, S Park, D Shen, XK Chu, CR Yu, M Abu-Asab, J Tuo, ... PloS one 9 (4), e95900, 2014 | 51 | 2014 |
