|The evolutionary history of lethal metastatic prostate cancer|
G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, J Tubio, ...
Nature 520 (7547), 353-357, 2015
|Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue|
CS Cooper, R Eeles, DC Wedge, P Van Loo, G Gundem, LB Alexandrov, ...
Nature genetics 47 (4), 367-372, 2015
|Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes|
JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ...
Science 345 (6196), 1251343, 2014
|Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer|
YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ...
elife 3, e02935, 2014
|Structural basis for the nuclear import of the human androgen receptor|
ML Cutress, HC Whitaker, IG Mills, M Stewart, DE Neal
Journal of cell science 121 (7), 957-968, 2008
|Integration of copy number and transcriptomics provides risk stratification in prostate cancer: a discovery and validation cohort study|
H Ross-Adams, AD Lamb, MJ Dunning, S Halim, J Lindberg, CM Massie, ...
EBioMedicine 2 (9), 1133-1144, 2015
|Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets|
DC Wedge, G Gundem, T Mitchell, DJ Woodcock, I Martincorena, M Ghori, ...
Nature genetics 50 (5), 682-692, 2018
|Engrailed-2 (EN2): a tumor specific urinary biomarker for the early diagnosis of prostate cancer|
R Morgan, A Boxall, A Bhatt, M Bailey, R Hindley, S Langley, HC Whitaker, ...
Clinical Cancer Research 17 (5), 1090-1098, 2011
|LYRIC/AEG-1 is targeted to different subcellular compartments by ubiquitinylation and intrinsic nuclear localization signals|
HJ Thirkettle, J Girling, AY Warren, IG Mills, K Sahadevan, H Leung, ...
Clinical Cancer Research 15 (9), 3003-3013, 2009
|Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging|
MD Allen, P Luong, C Hudson, J Leyton, B Delage, E Ghazaly, R Cutts, ...
Cancer research 74 (3), 896-907, 2014
|Peroxiredoxin-3 is overexpressed in prostate cancer and promotes cancer cell survival by protecting cells from oxidative stress|
HC Whitaker, D Patel, WJ Howat, AY Warren, JD Kay, T Sangan, ...
British journal of cancer 109 (4), 983-993, 2013
|Alterations in β‐catenin expression and localization in prostate cancer|
HC Whitaker, J Girling, AY Warren, H Leung, IG Mills, DE Neal
The Prostate 68 (11), 1196-1205, 2008
|The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine|
HC Whitaker, Z Kote-Jarai, H Ross-Adams, AY Warren, J Burge, A George, ...
PloS one 5 (10), e13363, 2010
|Nuclear LYRIC/AEG-1 interacts with PLZF and relieves PLZF-mediated repression|
HJ Thirkettle, IG Mills, HC Whitaker, DE Neal
Oncogene 28 (41), 3663-3670, 2009
|N-acetyl-L-aspartyl-L-glutamate peptidase-like 2 is overexpressed in cancer and promotes a pro-migratory and pro-metastatic phenotype|
HC Whitaker, LL Shiong, JD Kay, H Grönberg, AY Warren, A Seipel, ...
Oncogene 33 (45), 5274-5287, 2014
|The potential value of microseminoprotein‐β as a prostate cancer biomarker and therapeutic target|
HC Whitaker, AY Warren, R Eeles, Z Kote‐Jarai, DE Neal
The Prostate 70 (3), 333-340, 2010
|Five-year outcomes of magnetic resonance imaging–based active surveillance for prostate cancer: a large cohort study|
V Stavrinides, F Giganti, B Trock, S Punwani, C Allen, A Kirkham, ...
European urology 78 (3), 443-451, 2020
|The early effects of rapid androgen deprivation on human prostate cancer|
GL Shaw, H Whitaker, M Corcoran, MJ Dunning, H Luxton, J Kay, ...
European urology 70 (2), 214-218, 2016
|Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogens|
HC Whitaker, S Hanrahan, N Totty, SC Gamble, J Waxman, ACB Cato, ...
Clinical cancer research 10 (21), 7392-7401, 2004
|What type of prostate cancer is systematically overlooked by multiparametric magnetic resonance imaging? An analysis from the PROMIS cohort|
JM Norris, LMC Echeverria, SRJ Bott, LC Brown, N Burns-Cox, ...
European urology 78 (2), 163-170, 2020