| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13124* | 2021 |
| Presenilin 1 maintains lysosomal Ca2+ homeostasis via TRPML1 by regulating vATPase-mediated lysosome acidification JH Lee, MK McBrayer, DM Wolfe, LJ Haslett, A Kumar, Y Sato, PPY Lie, ... Cell reports 12 (9), 1430-1444, 2015 | 317 | 2015 |
| A release mechanism for stored ATP in ocular ciliary epithelial cells CH Mitchell, DA Carré, AM McGlinn, RA Stone, MM Civan Proceedings of the National Academy of Sciences 95 (12), 7174-7178, 1998 | 276 | 1998 |
| CATSPER Channel-Mediated Ca2+ Entry into Mouse Sperm Triggers a Tail-to-Head Propagation J Xia, D Reigada, CH Mitchell, D Ren Biology of reproduction 77 (3), 551-559, 2007 | 183 | 2007 |
| Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP EE Coffey, JM Beckel, AM Laties, CH Mitchell Neuroscience 263, 111-124, 2014 | 180 | 2014 |
| From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma D Križaj, DA Ryskamp, N Tian, G Tezel, CH Mitchell, VZ Slepak, ... Current eye research 39 (2), 105-119, 2014 | 167 | 2014 |
| Neurons respond directly to mechanical deformation with pannexin‐mediated ATP release and autostimulation of P2X7 receptors J Xia, JC Lim, W Lu, JM Beckel, EJ Macarak, AM Laties, CH Mitchell The Journal of physiology 590 (10), 2285-2304, 2012 | 167 | 2012 |
| Stimulation of P2X7 receptors elevates Ca2+ and kills retinal ganglion cells X Zhang, M Zhang, AM Laties, CH Mitchell Investigative ophthalmology & visual science 46 (6), 2183-2191, 2005 | 155 | 2005 |
| CALHM3 is essential for rapid ion channel-mediated purinergic neurotransmission of GPCR-mediated tastes Z Ma, A Taruno, M Ohmoto, M Jyotaki, JC Lim, H Miyazaki, N Niisato, ... Neuron 98 (3), 547-561. e10, 2018 | 152 | 2018 |
| Autophagy in the eye: implications for ocular cell health LS Frost, CH Mitchell, K Boesze-Battaglia Experimental eye research 124, 56-66, 2014 | 152 | 2014 |
| Mechanosensitive release of adenosine 5′‐triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: A … JM Beckel, AJ Argall, JC Lim, J Xia, W Lu, EE Coffey, EJ Macarak, ... Glia 62 (9), 1486-1501, 2014 | 151 | 2014 |
| Elevated pressure triggers a physiological release of ATP from the retina: possible role for pannexin hemichannels D Reigada, W Lu, M Zhang, CH Mitchell Neuroscience 157 (2), 396-404, 2008 | 151 | 2008 |
| Restoration of lysosomal pH in RPE cells from cultured human and ABCA4−/− mice: pharmacologic approaches and functional recovery J Liu, W Lu, D Reigada, J Nguyen, AM Laties, CH Mitchell Investigative ophthalmology & visual science 49 (2), 772-780, 2008 | 151 | 2008 |
| Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells GC Baltazar, S Guha, W Lu, J Lim, K Boesze-Battaglia, AM Laties, P Tyagi, ... PloS one 7 (12), e49635, 2012 | 140 | 2012 |
| Release of ATP by a human retinal pigment epithelial cell line: potential for autocrine stimulation through subretinal space CH Mitchell The Journal of physiology 534 (Pt 1), 193, 2001 | 130 | 2001 |
| Purines in the eye: recent evidence for the physiological and pathological role of purines in the RPE, retinal neurons, astrocytes, Müller cells, lens, trabecular meshwork … J Sanderson, DA Dartt, V Trinkaus-Randall, J Pintor, MM Civan, ... Experimental Eye Research 127, 270-279, 2014 | 128 | 2014 |
| The P2X7 receptor primes IL-1β and the NLRP3 inflammasome in astrocytes exposed to mechanical strain F Albalawi, W Lu, JM Beckel, JC Lim, SA McCaughey, CH Mitchell Frontiers in cellular neuroscience 11, 227, 2017 | 124 | 2017 |
| Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo H Hu, W Lu, M Zhang, X Zhang, AJ Argall, S Patel, GE Lee, YC Kim, ... Experimental eye research 91 (3), 425-432, 2010 | 122 | 2010 |
| Release of ATP from retinal pigment epithelial cells involves both CFTR and vesicular transport D Reigada, CH Mitchell American Journal of Physiology-Cell Physiology 288 (1), C132-C140, 2005 | 119 | 2005 |
| A3 adenosine receptors regulate Cl− channels of nonpigmented ciliary epithelial cells CH Mitchell, K Peterson-Yantorno, DA Carré, AM McGlinn, ... American Journal of Physiology-Cell Physiology 276 (3), C659-C666, 1999 | 119 | 1999 |
