Identification of bioactive constituents of Ziziphus jujube fruit extracts exerting antiproliferative and apoptotic effects in human breast cancer cells P Plastina, D Bonofiglio, D Vizza, A Fazio, D Rovito, C Giordano, I Barone, ... Journal of ethnopharmacology 140 (2), 325-332, 2012 | 223 | 2012 |
Estrogen receptor mutations and changes in downstream gene expression and signaling I Barone, L Brusco, SAW Fuqua Clinical Cancer Research 16 (10), 2702-2708, 2010 | 196 | 2010 |
Obesity, leptin and breast cancer: epidemiological evidence and proposed mechanisms S Andò, L Gelsomino, S Panza, C Giordano, D Bonofiglio, I Barone, ... Cancers 11 (1), 62, 2019 | 186 | 2019 |
Evidences that leptin up-regulates E-cadherin expression in breast cancer: effects on tumor growth and progression L Mauro, S Catalano, G Bossi, M Pellegrino, I Barone, S Morales, ... Cancer research 67 (7), 3412-3421, 2007 | 147 | 2007 |
Omega‐3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPARγ activation in MCF‐7 breast cancer cells D Rovito, C Giordano, D Vizza, P Plastina, I Barone, I Casaburi, ... Journal of Cellular Physiology 228 (6), 1314-1322, 2013 | 142 | 2013 |
Estrogen receptor beta as a novel target of androgen receptor action in breast cancer cell lines P Rizza, I Barone, D Zito, F Giordano, M Lanzino, F De Amicis, L Mauro, ... Breast cancer research 16, 1-13, 2014 | 137 | 2014 |
Leptin mediates tumor–stromal interactions that promote the invasive growth of breast cancer cells I Barone, S Catalano, L Gelsomino, S Marsico, C Giordano, S Panza, ... Cancer research 72 (6), 1416-1427, 2012 | 137 | 2012 |
Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation S Catalano, C Giordano, P Rizza, G Gu, I Barone, D Bonofiglio, ... Journal of cellular physiology 218 (3), 490-500, 2009 | 136 | 2009 |
AR collaborates with ERα in aromatase inhibitor-resistant breast cancer Y Rechoum, D Rovito, D Iacopetta, I Barone, S Andò, NL Weigel, ... Breast cancer research and treatment 147, 473-485, 2014 | 131 | 2014 |
Human sperm express a functional androgen receptor: effects on PI3K/AKT pathway S Aquila, E Middea, S Catalano, S Marsico, M Lanzino, I Casaburi, ... Human Reproduction 22 (10), 2594-2605, 2007 | 114 | 2007 |
Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth S Catalano, C Giordano, S Panza, F Chemi, D Bonofiglio, M Lanzino, ... Breast cancer research and treatment 146, 273-285, 2014 | 113 | 2014 |
The weight of obesity in breast cancer progression and metastasis: Clinical and molecular perspectives I Barone, C Giordano, D Bonofiglio, S Ando, S Catalano Seminars in cancer biology 60, 274-284, 2020 | 106 | 2020 |
The multifaceted mechanism of leptin signaling within tumor microenvironment in driving breast cancer growth and progression S Andò, I Barone, C Giordano, D Bonofiglio, S Catalano Frontiers in oncology 4, 340, 2014 | 101 | 2014 |
Leptin increases HER2 protein levels through a STAT3-mediated up-regulation of Hsp90 in breast cancer cells C Giordano, D Vizza, S Panza, I Barone, D Bonofiglio, M Lanzino, D Sisci, ... Molecular oncology 7 (3), 379-391, 2013 | 93 | 2013 |
Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1‐mediated p53 activation G Gu, I Barone, L Gelsomino, C Giordano, D Bonofiglio, G Statti, ... Journal of cellular physiology 227 (10), 3363-3372, 2012 | 93 | 2012 |
Rapid estradiol/ERα signaling enhances aromatase enzymatic activity in breast cancer cells S Catalano, I Barone, C Giordano, P Rizza, H Qi, G Gu, R Malivindi, ... Molecular endocrinology 23 (10), 1634-1645, 2009 | 91 | 2009 |
Expression of the K303R estrogen receptor-α breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway I Barone, Y Cui, MH Herynk, A Corona-Rodriguez, C Giordano, J Selever, ... Cancer research 69 (11), 4724-4732, 2009 | 91 | 2009 |
Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity C Giordano, F Chemi, S Panza, I Barone, D Bonofiglio, M Lanzino, ... Oncotarget 7 (2), 1262, 2016 | 84 | 2016 |
Leptin, obesity and breast cancer: progress to understanding the molecular connections I Barone, C Giordano, D Bonofiglio, S Andò, S Catalano Current Opinion in Pharmacology 31, 83-89, 2016 | 77 | 2016 |
Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression C Giordano, S Catalano, S Panza, D Vizza, I Barone, D Bonofiglio, ... Oncogene 30 (39), 4129-4140, 2011 | 74 | 2011 |