| Proteome analysis reveals phosphorylation of ATP synthase β-subunit in human skeletal muscle and proteins with potential roles in type 2 diabetes K Højlund, K Wrzesinski, PM Larsen, SJ Fey, P Roepstorff, A Handberg, ... Journal of Biological Chemistry 278 (12), 10436-10442, 2003 | 301 | 2003 |
| Determination of drug toxicity using 3D spheroids constructed from an immortal human hepatocyte cell line SJ Fey, K Wrzesinski Toxicological sciences 127 (2), 403-411, 2012 | 215 | 2012 |
| Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes X Zhao, IR Leon, S Bak, M Mogensen, K Wrzesinski, K Højlund, ... Molecular & cellular proteomics 10 (1), 2011 | 200 | 2011 |
| Effect of acid shock on protein expression by biofilm cells of Streptococcus mutans J Welin, JC Wilkins, D Beighton, K Wrzesinski, SJ Fey, P Mose-Larsen, ... FEMS microbiology letters 227 (2), 287-293, 2003 | 88 | 2003 |
| IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis T Sparre, U Bjerre Christensen, P Mose Larsen, S Fey, K Wrzesinski, ... Diabetologia 45, 1550-1561, 2002 | 72 | 2002 |
| The cultural divide: exponential growth in classical 2D and metabolic equilibrium in 3D environments K Wrzesinski, A Rogowska-Wrzesinska, R Kanlaya, K Borkowski, ... PloS one 9 (9), e106973, 2014 | 67 | 2014 |
| Top-down and Middle-down Protein Analysis Reveals That Intact and Clipped Human Histones Differ in Post-Translational Modification Patterns*[S] A Tvardovskiy, K Wrzesinski, S Sidoli, SJ Fey, A Rogowska-Wrzesinska, ... Molecular & Cellular Proteomics 14 (12), 3142-3153, 2015 | 66 | 2015 |
| Immune-mediated β-cell destruction in vitro and in vivo—A pivotal role for galectin-3 AE Karlsen, ZM Størling, T Sparre, MR Larsen, A Mahmood, J Størling, ... Biochemical and biophysical research communications 344 (1), 406-415, 2006 | 57 | 2006 |
| After trypsinisation, 3D spheroids of C3A hepatocytes need 18 days to re-establish similar levels of key physiological functions to those seen in the liver K Wrzesinski, SJ Fey Toxicology research 2 (2), 123-135, 2013 | 55 | 2013 |
| HepG2/C3A 3D spheroids exhibit stable physiological functionality for at least 24 days after recovering from trypsinisation K Wrzesinski, MC Magnone, LV Hansen, ME Kruse, T Bergauer, ... Toxicology research 2 (3), 163-172, 2013 | 52 | 2013 |
| From 2D to 3D-a new dimension for modelling the effect of natural products on human tissue K Wrzesinski, S J Fey Current Pharmaceutical Design 21 (38), 5605-5616, 2015 | 51 | 2015 |
| Hepatocellular carcinoma (HepG2/C3A) cell-based 3D model for genotoxicity testing of chemicals M Štampar, HS Frandsen, A Rogowska-Wrzesinska, K Wrzesinski, ... Science of the Total Environment 755, 143255, 2021 | 45 | 2021 |
| Metabolic reprogramming and the recovery of physiological functionality in 3D cultures in micro-bioreactors K Wrzesinski, SJ Fey Bioengineering 5 (1), 22, 2018 | 36 | 2018 |
| Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspective C Calitz, JH Hamman, SJ Fey, K Wrzesinski, C Gouws Toxicology mechanisms and methods 28 (5), 369-385, 2018 | 31 | 2018 |
| Characterization of an alginate encapsulated LS180 spheroid model for anti-colorectal cancer compound screening T Smit, C Calitz, C Willers, H Svitina, J Hamman, SJ Fey, C Gouws, ... ACS medicinal chemistry letters 11 (5), 1014-1021, 2020 | 20 | 2020 |
| Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids K Wojdyla, K Wrzesinski, J Williamson, SJ Fey, A Rogowska-Wrzesinska Toxicology Research 5 (3), 905-920, 2016 | 20 | 2016 |
| Proteomics identifies molecular networks affected by tetradecylthioacetic acid and fish oil supplemented diets K Wrzesinski, IR León, K Kulej, RR Sprenger, B Bjørndal, BJ Christensen, ... Journal of proteomics 84, 61-77, 2013 | 20 | 2013 |
| Cell-free DNA in a three-dimensional spheroid cell culture model: A preliminary study J Aucamp, C Calitz, AJ Bronkhorst, K Wrzesinski, S Hamman, C Gouws, ... The International Journal of Biochemistry & Cell Biology 89, 182-192, 2017 | 19 | 2017 |
| Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short-term exposure to two-dimensional and three-dimensional spheroid cell … C Calitz, JH Hamman, AM Viljoen, SJ Fey, K Wrzesinski, C Gouws Toxicology mechanisms and methods 28 (9), 641-652, 2018 | 14 | 2018 |
| Anticancer Potential of Sutherlandia frutescens and Xysmalobium undulatum in LS180 Colorectal Cancer Mini-Tumors C Gouws, T Smit, C Willers, H Svitina, C Calitz, K Wrzesinski Molecules 26 (3), 605, 2021 | 12 | 2021 |
