Calculation of relative electron impact total ionization cross sections for organic molecules WL Fitch, AD Sauter Analytical chemistry 55 (6), 832-835, 1983 | 298 | 1983 |
High-resolution 1H NMR in solid-phase organic synthesis WL Fitch, G Detre, CP Holmes, JN Shoolery, PA Keifer The Journal of Organic Chemistry 59 (26), 7955-7956, 1994 | 296 | 1994 |
Alkaloid and predation patterns in Colorado lupine populations PM Dolinger, PR Ehrlich, WL Fitch, DE Breedlove Oecologia 13, 191-204, 1973 | 164 | 1973 |
Metabolic activation of nevirapine in human liver microsomes: dehydrogenation and inactivation of cytochrome P450 3A4 B Wen, Y Chen, WL Fitch Drug Metabolism and Disposition 37 (7), 1557-1562, 2009 | 101 | 2009 |
Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study T Reid, B Oronsky, J Scicinski, CL Scribner, SJ Knox, S Ning, DM Peehl, ... The Lancet Oncology 16 (9), 1133-1142, 2015 | 97 | 2015 |
Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine WG Park, M Wu, R Bowen, M Zheng, WL Fitch, RK Pai, D Wodziak, ... Gastrointestinal endoscopy 78 (2), 295-302. e2, 2013 | 94 | 2013 |
Identification of metabolites in Withania sominfera fruits by liquid chromatography and high‐resolution mass spectrometry J Bolleddula, W Fitch, SK Vareed, MG Nair Rapid communications in mass spectrometry 26 (11), 1277-1290, 2012 | 86 | 2012 |
Chemiluminescent nitrogen detection for HPLC: an important new tool in organic analytical chemistry WL Fitch, AK Szardenings, EM Fujinari Tetrahedron letters 38 (10), 1689-1692, 1997 | 81 | 1997 |
Agonists of the follicle stimulating hormone receptor from an encoded thiazolidinone library D Maclean, F Holden, AM Davis, RA Scheuerman, S Yanofsky, ... Journal of Combinatorial Chemistry 6 (2), 196-206, 2004 | 79 | 2004 |
Methods for hard-tagging an encoded synthetic library MA Gallop, E Gordon, ZJ Ni, D MacLean, C Holmes, W Fitch, N Shah US Patent 6,368,874, 2002 | 78 | 2002 |
Methods for hard-tagging an encoded synthetic library MA Gallop, E Gordon, ZJ Ni, D MacLean, C Holmes, W Fitch, N Shah US Patent 5,846,839, 1998 | 70 | 1998 |
Analytical tools and approaches for metabolite identification in early drug discovery Y Chen, M Monshouwer, WL Fitch Pharmaceutical research 24, 248-257, 2007 | 68 | 2007 |
Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q‐trap mass spectrometry B Wen, WL Fitch Journal of mass spectrometry 44 (1), 90-100, 2009 | 67 | 2009 |
Analytical strategies for the screening and evaluation of chemically reactive drug metabolites B Wen, WL Fitch Expert opinion on drug metabolism & toxicology 5 (1), 39-55, 2009 | 61 | 2009 |
Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction T Nishimura, Y Hu, M Wu, E Pham, H Suemizu, M Elazar, M Liu, R Idilman, ... Journal of Pharmacology and Experimental Therapeutics 344 (2), 388-396, 2013 | 60 | 2013 |
New methods for analyzing compounds on polymeric supports MA Gallop, WL Fitch Current Opinion in Chemical Biology 1 (1), 94-100, 1997 | 58 | 1997 |
RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials B Oronsky, R Paulmurugan, K Foygel, J Scicinski, SJ Knox, D Peehl, ... Expert opinion on investigational drugs 26 (1), 109-119, 2017 | 56 | 2017 |
Preclinical evaluation of the metabolism and disposition of RRx-001, a novel investigative anticancer agent J Scicinski, B Oronsky, M Taylor, G Luo, T Musick, J Marini, CM Adams, ... Drug Metabolism and Disposition 40 (9), 1810-1816, 2012 | 56 | 2012 |
Quantitative comparison of combined gas chromatographic/mass spectrometric profiles of complex mixtures DH Smith, M Achenbach, WJ Yeager, PJ Anderson, WL Fitch, ... Analytical Chemistry 49 (11), 1623-1632, 1977 | 56 | 1977 |
Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH: cytochrome P450 reductase B Wen, KJ Coe, P Rademacher, WL Fitch, M Monshouwer, SD Nelson Chemical research in toxicology 21 (12), 2393-2406, 2008 | 54 | 2008 |