| Total synthesis of calicheamicin. gamma. 1I. 3. The final stages KC Nicolaou, CW Hummel, M Nakada, K Shibayama, EN Pitsinos, ... Journal of the American Chemical Society 115 (17), 7625-7635, 1993 | 180 | 1993 |
| Biomimetic total synthesis of bisorbicillinol, bisorbibutenolide, trichodimerol, and designed analogues of the bisorbicillinoids KC Nicolaou, G Vassilikogiannakis, KB Simonsen, PS Baran, YL Zhong, ... Journal of the American Chemical Society 122 (13), 3071-3079, 2000 | 175 | 2000 |
| Analogs of calicheamicin gamma1I, method of making and using the same KC Nicolaou, AL Smith, CK Hwang, E Pitsinos US Patent 5,264,586, 1993 | 171 | 1993 |
| Total synthesis of calicheamicin. gamma. 1I KC Nicolaou, CW Hummel, EN Pitsinos, M Nakada, AL Smith, ... Journal of the American Chemical Society 114 (25), 10082-10084, 1992 | 160 | 1992 |
| Tumor necrosis factor-α promotes malignant pleural effusion GT Stathopoulos, A Kollintza, C Moschos, I Psallidas, TP Sherrill, ... Cancer research 67 (20), 9825-9834, 2007 | 137 | 2007 |
| Total synthesis of calicheamicin. gamma. 1I. 2. Development of an enantioselective route to (-)-calicheamicinone AL Smith, EN Pitsinos, CK Hwang, Y Mizuno, H Saimoto, GR Scarlato, ... Journal of the American Chemical Society 115 (17), 7612-7624, 1993 | 136 | 1993 |
| Diaryl ether formation in the synthesis of natural products EN Pitsinos, VP Vidali, EA Couladouros European Journal of Organic Chemistry 2011 (7), 1207-1222, 2011 | 121 | 2011 |
| Inhibition of topoisomerase I by naphthoquinone derivatives ZF Plyta, T Li, VP Papageorgiou, AS Mellidis, AN Assimopoulou, ... Bioorganic & medicinal chemistry letters 8 (23), 3385-3390, 1998 | 114 | 1998 |
| Biomimetic explorations towards the bisorbicillinoids: total synthesis of bisorbicillinol, bisorbibutenolide, and trichodimerol KC Nicolaou, KB Simonsen, G Vassilikogiannakis, PS Baran, VP Vidali, ... Angewandte Chemie International Edition 38 (23), 3555-3559, 1999 | 108 | 1999 |
| Enantioselective total synthesis of (-)-calicheamicinone AL Smith, CK Hwang, E Pitsinos, GR Scarlato, KC Nicolaou Journal of the American Chemical Society 114 (8), 3134-3136, 1992 | 98 | 1992 |
| Streamlined total synthesis of uncialamycin and its application to the synthesis of designed analogues for biological investigations KC Nicolaou, Y Wang, M Lu, D Mandal, MR Pattanayak, R Yu, AA Shah, ... Journal of the American Chemical Society 138 (26), 8235-8246, 2016 | 81 | 2016 |
| Calicheamicin mimics KC Nicolaou, EN Pitsinos US Patent 5,550,246, 1996 | 78 | 1996 |
| A water‐soluble prodrug of taxol with self‐assembling properties KC Nicolaou, RK Guy, EN Pitsinos, W Wrasidlo Angewandte Chemie International Edition in English 33 (15‐16), 1583-1587, 1994 | 76 | 1994 |
| A Novel 2‘-(N-Methylpyridinium Acetate) Prodrug of Paclitaxel Induces Superior Antitumor Responses in Preclinical Cancer Models W Wrasidlo, G Gaedicke, RK Guy, J Renaud, E Pitsinos, KC Nicolaou, ... Bioconjugate chemistry 13 (5), 1093-1099, 2002 | 46 | 2002 |
| Synthetic calicheamicin mimics with novel initiation mechanisms: DNA cleavage, cytotoxicity, and apoptosis KC Nicolaou, EN Pitsinos, EA Theodorakis, H Saimoto, W Wrasidlo Chemistry & Biology 1 (1), 57-66, 1994 | 44 | 1994 |
| Total synthesis and biological evaluation of tiancimycins A and B, yangpumicin A, and related anthraquinone-fused enediyne antitumor antibiotics KC Nicolaou, D Das, Y Lu, S Rout, EN Pitsinos, J Lyssikatos, A Schammel, ... Journal of the American Chemical Society 142 (5), 2549-2561, 2020 | 39 | 2020 |
| Short and efficient route to the fully functionalized polar core of scyphostatin EN Pitsinos, A Cruz Organic Letters 7 (11), 2245-2248, 2005 | 39 | 2005 |
| A general method for the synthesis of bastaranes and isobastaranes: first total synthesis of bastadins 5, 10, 12, 16, 20, and 21 EA Couladouros, EN Pitsinos, VI Moutsos, G Sarakinos Chemistry–A European Journal 11 (1), 406-421, 2005 | 38 | 2005 |
| Streamlined total synthesis of shishijimicin A and its application to the design, synthesis, and biological evaluation of analogues thereof and practical syntheses of PhthNSSMe … KC Nicolaou, R Li, Z Lu, EN Pitsinos, LB Alemany, M Aujay, C Lee, ... Journal of the American Chemical Society 140 (38), 12120-12136, 2018 | 37 | 2018 |
| Total synthesis of (+)-scyphostatin featuring an enantioselective and highly efficient route to the side-chain via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA) E Pitsinos, N Athinaios, Z Xu, G Wang, E Negishi Chemical communications 46 (13), 2200-2202, 2010 | 36 | 2010 |
Kyriacos NicolaouRice UniversityПодтвержден адрес электронной почты в домене rice.edu
