α9‐and α7‐containing receptors mediate the pro‐proliferative effects of nicotine in the A549 adenocarcinoma cell line V Mucchietto, F Fasoli, S Pucci, M Moretti, R Benfante, A Maroli, ... British journal of pharmacology 175 (11), 1957-1972, 2018 | 72 | 2018 |
A short entry to enantiopure 2-substituted 1, 4-benzodioxanes by efficient resolution methods C Bolchi, L Fumagalli, B Moroni, M Pallavicini, E Valoti Tetrahedron: Asymmetry 14 (23), 3779-3785, 2003 | 55 | 2003 |
Benzodioxane–benzamides as new bacterial cell division inhibitors G Chiodini, M Pallavicini, C Zanotto, M Bissa, A Radaelli, V Straniero, ... European journal of medicinal chemistry 89, 252-265, 2015 | 51 | 2015 |
Structure–affinity studies for a novel series of homochiral naphtho and tetrahydronaphtho analogues of α1 antagonist WB-4101 C Bolchi, P Catalano, L Fumagalli, M Gobbi, M Pallavicini, A Pedretti, ... Bioorganic & medicinal chemistry 12 (18), 4937-4951, 2004 | 47 | 2004 |
Predicting the physicochemical profile of diastereoisomeric histidine‐containing dipeptides by property space analysis G Vistoli, V Straniero, A Pedretti, L Fumagalli, C Bolchi, M Pallavicini, ... Chirality 24 (7), 566-576, 2012 | 36 | 2012 |
WB4101-Related Compounds: New, Subtype-Selective α1-Adrenoreceptor Antagonists (or Inverse Agonists?) M Pallavicini, R Budriesi, L Fumagalli, P Ioan, A Chiarini, C Bolchi, ... Journal of medicinal chemistry 49 (24), 7140-7149, 2006 | 36 | 2006 |
Highly efficient resolutions of 1, 4-benzodioxane-2-carboxylic acid with para substituted 1-phenylethylamines C Bolchi, M Pallavicini, L Fumagalli, N Marchini, B Moroni, C Rusconi, ... Tetrahedron: Asymmetry 16 (9), 1639-1643, 2005 | 33 | 2005 |
Ten years of fentanyl-like drugs: a technical-analytical review G Roda, F Faggiani, C Bolchi, M Pallavicini, M Dei Cas Analytical Sciences 35 (5), 479-491, 2019 | 32 | 2019 |
6-Methoxy-7-benzofuranoxy and 6-Methoxy-7-indolyloxy Analogues of 2-[2-(2, 6-Dimethoxyphenoxy) ethyl] aminomethyl-1, 4-benzodioxane (WB4101): 1 Discovery of a Potent and … L Fumagalli, M Pallavicini, R Budriesi, C Bolchi, M Canovi, A Chiarini, ... Journal of medicinal chemistry 56 (16), 6402-6412, 2013 | 32 | 2013 |
3-(Benzodioxan-2-ylmethoxy)-2, 6-difluorobenzamides bearing hydrophobic substituents at the 7-position of the benzodioxane nucleus potently inhibit methicillin-resistant Sa and … V Straniero, M Pallavicini, G Chiodini, C Zanotto, L Volontè, A Radaelli, ... European journal of medicinal chemistry 120, 227-243, 2016 | 31 | 2016 |
One-pot racemization process of 1-phenyl-1, 2, 3, 4-tetrahydroisoquinoline: A key intermediate for the antimuscarinic agent solifenacin C Bolchi, M Pallavicini, L Fumagalli, V Straniero, E Valoti Organic Process Research & Development 17 (3), 432-437, 2013 | 31 | 2013 |
Unichiral 2-(2′-Pyrrolidinyl)-1,4-benzodioxanes: the 2R,2′S Diastereomer of the N-Methyl-7-hydroxy Analogue Is a Potent α4β2- and α6β2-Nicotinic … C Bolchi, C Gotti, M Binda, L Fumagalli, L Pucci, F Pistillo, G Vistoli, ... Journal of medicinal chemistry 54 (21), 7588-7601, 2011 | 31 | 2011 |
QSAR study for a novel series of ortho monosubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101 L Fumagalli, C Bolchi, S Colleoni, M Gobbi, B Moroni, M Pallavicini, ... Bioorganic & medicinal chemistry 13 (7), 2547-2559, 2005 | 29 | 2005 |
Chemistry and pharmacology of a series of unichiral analogues of 2-(2-pyrrolidinyl)-1, 4-benzodioxane, prolinol phenyl ether, and prolinol 3-pyridyl ether designed as α4β2 … C Bolchi, E Valoti, C Gotti, F Fasoli, P Ruggeri, L Fumagalli, M Binda, ... Journal of Medicinal Chemistry 58 (16), 6665-6677, 2015 | 28 | 2015 |
Resolution of 2-substituted 1, 4-benzodioxanes by entrainment C Bolchi, M Pallavicini, L Fumagalli, C Rusconi, M Binda, E Valoti Tetrahedron: Asymmetry 18 (9), 1038-1041, 2007 | 28 | 2007 |
1, 4-Benzodioxane, an evergreen, versatile scaffold in medicinal chemistry: A review of its recent applications in drug design C Bolchi, F Bavo, R Appiani, G Roda, M Pallavicini European Journal of Medicinal Chemistry 200, 112419, 2020 | 27 | 2020 |
QSAR study for a novel series of ortho disubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101 M Pallavicini, L Fumagalli, M Gobbi, C Bolchi, S Colleoni, B Moroni, ... European journal of medicinal chemistry 41 (9), 1025-1040, 2006 | 27 | 2006 |
Peptidomimetic inhibitors of farnesyltransferase with high in vitro activity and significant cellular potency C Bolchi, M Pallavicini, C Rusconi, L Diomede, N Ferri, A Corsini, ... Bioorganic & medicinal chemistry letters 17 (22), 6192-6196, 2007 | 25 | 2007 |
Resolution of 5-hydroxymethyl-2-oxazolidinone by preferential crystallization and investigations on the nature of the racemates of some 2-oxazolidinone derivatives M Pallavicini, C Bolchi, R Di Pumpo, L Fumagalli, B Moroni, E Valoti, ... Tetrahedron: Asymmetry 15 (10), 1659-1665, 2004 | 25 | 2004 |
Affinity and activity profiling of unichiral 8-substituted 1, 4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist L Fumagalli, M Pallavicini, R Budriesi, M Gobbi, V Straniero, M Zagami, ... European journal of medicinal chemistry 58, 184-191, 2012 | 24 | 2012 |