| Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension T Bertero, WM Oldham, KA Cottrill, S Pisano, RR Vanderpool, Q Yu, ... The Journal of clinical investigation 126 (9), 3313-3335, 2016 | 357 | 2016 |
| Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases KS Montine, JF Quinn, J Zhang, JP Fessel, LJ Roberts II, JD Morrow, ... Chemistry and Physics of Lipids 128 (1-2), 117-124, 2004 | 267 | 2004 |
| Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension JP Fessel, NA Porter, KP Moore, JR Sheller, LJ Roberts Proceedings of the National Academy of Sciences 99 (26), 16713-16718, 2002 | 241 | 2002 |
| Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension JP Fessel, NA Porter, KP Moore, JR Sheller, LJ Roberts Proceedings of the National Academy of Sciences 99 (26), 16713-16718, 2002 | 241 | 2002 |
| Sirt3 impairment and SOD2 hyperacetylation in vascular oxidative stress and hypertension AE Dikalova, HA Itani, RR Nazarewicz, WG McMaster, CR Flynn, ... Circulation research 121 (5), 564-574, 2017 | 234 | 2017 |
| A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension AR Hemnes, A Rathinasabapathy, EA Austin, EL Brittain, EJ Carrier, ... European Respiratory Journal 51 (6), 2018 | 214 | 2018 |
| Fatty acid metabolic defects and right ventricular lipotoxicity in human pulmonary arterial hypertension EL Brittain, M Talati, JP Fessel, H Zhu, N Penner, MW Calcutt, JD West, ... Circulation 133 (20), 1936-1944, 2016 | 199 | 2016 |
| A metabolic basis for endothelial-to-mesenchymal transition J Xiong, H Kawagishi, Y Yan, J Liu, QS Wells, LR Edmunds, ... Molecular cell 69 (4), 689-698. e7, 2018 | 189 | 2018 |
| Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension AR Hemnes, EL Brittain, AW Trammell, JP Fessel, ED Austin, N Penner, ... American journal of respiratory and critical care medicine 189 (3), 325-334, 2014 | 168 | 2014 |
| Oxidative mediated lipid peroxidation recapitulates proarrhythmic effects on cardiac sodium channels K Fukuda, SS Davies, T Nakajima, BH Ong, S Kupershmidt, J Fessel, ... Circulation research 97 (12), 1262-1269, 2005 | 168 | 2005 |
| The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation LJ Roberts II, JP Fessel Chemistry and physics of lipids 128 (1-2), 173-186, 2004 | 151 | 2004 |
| Orthostatic hypertension: when pressor reflexes overcompensate J Fessel, D Robertson Nature Clinical Practice Nephrology 2 (8), 424-431, 2006 | 142 | 2006 |
| Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming JP Fessel, R Hamid, BM Wittmann, LJ Robinson, T Blackwell, Y Tada, ... Pulmonary circulation 2 (2), 201-213, 2012 | 136 | 2012 |
| The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation LJ Roberts, JP Fessel, SS Davies Brain Pathology 15 (2), 143-148, 2005 | 129 | 2005 |
| A potential role for insulin resistance in experimental pulmonary hypertension J West, KD Niswender, JA Johnson, ME Pugh, L Gleaves, JP Fessel, ... European Respiratory Journal 41 (4), 861-871, 2013 | 120 | 2013 |
| Plasma biomarkers of oxidant stress and development of organ failure in severe sepsis LB Ware, JP Fessel, AK May, II L Jackson Roberts Shock 36 (1), 12-17, 2011 | 111 | 2011 |
| Isofurans, but not F2‐isoprostanes, are increased in the substantia nigra of patients with Parkinson's disease and with dementia with Lewy body disease JP Fessel, C Hulette, S Powell, LJ Roberts, J Zhang Journal of neurochemistry 85 (3), 645-650, 2003 | 106 | 2003 |
| Estrogen metabolite 16α-hydroxyestrone exacerbates bone morphogenetic protein receptor type II–associated pulmonary arterial hypertension through microRNA-29–mediated … X Chen, M Talati, JP Fessel, AR Hemnes, S Gladson, J French, S Shay, ... Circulation 133 (1), 82-97, 2016 | 97 | 2016 |
| Mechanisms of lipid accumulation in the bone morphogenetic protein receptor type 2 mutant right ventricle MH Talati, EL Brittain, JP Fessel, N Penner, J Atkinson, M Funke, ... American journal of respiratory and critical care medicine 194 (6), 719-728, 2016 | 85 | 2016 |
| Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling K Chow, JP Fessel, Kaoriihida-Stansbury, EP Schmidt, C Gaskill, ... Pulmonary circulation 3 (1), 31-49, 2013 | 80 | 2013 |
