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Christopher R Shaler
Christopher R Shaler
Sonata Therapeutics
Подтвержден адрес электронной почты в домене sonatatx.com
Название
Процитировано
Процитировано
Год
Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung
CL Small, CR Shaler, S McCormick, M Jeyanathan, D Damjanovic, ...
The Journal of Immunology 184 (4), 2048-2056, 2010
2562010
MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate …
CR Shaler, J Choi, PT Rudak, A Memarnejadian, PA Szabo, ...
PLoS biology 15 (6), e2001930, 2017
1452017
Within the Enemy’s Camp: contribution of the granuloma to the dissemination, persistence and transmission of Mycobacterium tuberculosis
CR Shaler, CN Horvath, M Jeyanathan, Z Xing
Frontiers in immunology 4, 30, 2013
902013
Mechanisms of delayed anti-tuberculosis protection in the lung of parenteral BCG-vaccinated hosts: a critical role of airway luminal T cells
CN Horvath, CR Shaler, M Jeyanathan, A Zganiacz, Z Xing
Mucosal immunology 5 (4), 420-431, 2012
792012
Understanding delayed T-cell priming, lung recruitment, and airway luminal T-cell responses in host defense against pulmonary tuberculosis
CR Shaler, C Horvath, R Lai, Z Xing
Journal of Immunology Research 2012, 2012
792012
Murine Airway Luminal Antituberculosis Memory CD8 T Cells by Mucosal Immunization Are Maintained Via Antigen-Driven In Situ Proliferation, Independent of …
M Jeyanathan, J Mu, S McCormick, D Damjanovic, CL Small, CR Shaler, ...
American journal of respiratory and critical care medicine 181 (8), 862-872, 2010
772010
Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway
VC Anipindi, P Bagri, K Roth, SE Dizzell, PV Nguyen, CR Shaler, DK Chu, ...
PLoS pathogens 12 (5), e1005589, 2016
692016
Mucosa-associated invariant T cells infiltrate hepatic metastases in patients with colorectal carcinoma but are rendered dysfunctional within and adjacent to tumor microenvironment
CR Shaler, ME Tun-Abraham, AI Skaro, K Khazaie, AJ Corbett, T Mele, ...
Cancer Immunology, Immunotherapy 66, 1563-1575, 2017
672017
PD-1 blockade promotes epitope spreading in anticancer CD8+ T cell responses by preventing fratricidal death of subdominant clones to relieve immunodomination
A Memarnejadian, CE Meilleur, CR Shaler, K Khazaie, JR Bennink, ...
The Journal of Immunology 199 (9), 3348-3359, 2017
672017
Continuous and discontinuous cigarette smoke exposure differentially affects protective Th1 immunity against pulmonary tuberculosis
CR Shaler, CN Horvath, S McCormick, M Jeyanathan, A Khera, ...
PLoS One 8 (3), e59185, 2013
672013
Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe?
SMM Haeryfar, CR Shaler, PT Rudak
Cancer Immunology, Immunotherapy 67 (12), 1885-1896, 2018
582018
Respiratory mucosal immunization with adenovirus gene transfer vector induces helper CD4 T cell‐independent protective immunity
J Mu, M Jeyanathan, CR Shaler, C Horvath, D Damjanovic, A Zganiacz, ...
The journal of gene medicine 12 (8), 693-704, 2010
552010
Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity
M Jeyanathan, D Damjanovic, CR Shaler, R Lai, M Wortzman, C Yin, ...
Mucosal immunology 6 (3), 612-625, 2013
512013
Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells
M Jeyanathan, S McCormick, R Lai, S Afkhami, CR Shaler, CN Horvath, ...
Mucosal immunology 7 (3), 670-683, 2014
412014
CD1d-and MR1-restricted T cells in sepsis
PA Szabo, RV Anantha, CR Shaler, JK McCormick, SMM Haeryfar
Frontiers in Immunology 6, 401, 2015
372015
Mucosal-associated invariant T cells in chronic inflammatory liver disease
FJ Bolte, B Rehermann
Seminars in liver disease 38 (01), 060-065, 2018
362018
The unique lifestyle of Crohn's disease-associated adherent-invasive Escherichia coli
CR Shaler, W Elhenawy, BK Coombes
Journal of molecular biology 431 (16), 2970-2981, 2019
342019
Pulmonary mycobacterial granuloma: increased IL-10 production contributes to establishing a symbiotic host–microbe microenvironment
CR Shaler, K Kugathasan, S McCormick, D Damjanovic, C Horvath, ...
The American journal of pathology 178 (4), 1622-1634, 2011
312011
Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts
CR Shaler, AA Parco, W Elhenawy, J Dourka, J Jury, EF Verdu, ...
Nature Communications 12 (1), 6664, 2021
282021
Therapeutic control of leishmaniasis by inhibitors of the mammalian target of rapamycin
F Khadir, CR Shaler, A Oryan, PT Rudak, DM Mazzuca, T Taheri, ...
PLoS Neglected Tropical Diseases 12 (8), e0006701, 2018
282018
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