| Enhancement of proteasome activity by a small-molecule inhibitor of USP14 BH Lee, MJ Lee, S Park, DC Oh, S Elsasser, PC Chen, C Gartner, ... Nature 467 (7312), 179-184, 2010 | 994 | 2010 |
| Deep multilayer brain proteomics identifies molecular networks in Alzheimer’s disease progression B Bai, X Wang, Y Li, PC Chen, K Yu, KK Dey, JM Yarbro, X Han, BM Lutz, ... Neuron 105 (6), 975-991. e7, 2020 | 344 | 2020 |
| U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, ... Proceedings of the National Academy of Sciences 110 (41), 16562-16567, 2013 | 302 | 2013 |
| Inhibition of xanthine oxidase and suppression of intracellular reactive oxygen species in HL-60 cells by theaflavin-3, 3 ‘-digallate,(−)-epigallocatechin-3-gallate, and propyl … JK Lin, PC Chen, CT Ho, SY Lin-Shiau Journal of Agricultural and Food Chemistry 48 (7), 2736-2743, 2000 | 250 | 2000 |
| The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions PC Chen, LN Qin, XM Li, BJ Walters, JA Wilson, L Mei, SM Wilson Journal of Neuroscience 29 (35), 10909-10919, 2009 | 134 | 2009 |
| Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer’s disease H Wang, KK Dey, PC Chen, Y Li, M Niu, JH Cho, X Wang, B Bai, Y Jiao, ... Molecular neurodegeneration 15, 1-20, 2020 | 126 | 2020 |
| Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer’s disease KK Dey, H Wang, M Niu, B Bai, X Wang, Y Li, JH Cho, H Tan, A Mishra, ... Clinical proteomics 16, 1-12, 2019 | 112 | 2019 |
| Ubiquitin homeostasis is critical for synaptic development and function PC Chen, BJ Bhattacharyya, J Hanna, H Minkel, JA Wilson, D Finley, ... Journal of Neuroscience 31 (48), 17505-17513, 2011 | 110 | 2011 |
| Proteomic landscape of Alzheimer’s Disease: novel insights into pathogenesis and biomarker discovery B Bai, D Vanderwall, Y Li, X Wang, S Poudel, H Wang, KK Dey, PC Chen, ... Molecular neurodegeneration 16 (1), 55, 2021 | 106 | 2021 |
| Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activity BJ Walters, SL Campbell, PC Chen, AP Taylor, DG Schroeder, ... Molecular and Cellular Neuroscience 39 (4), 539-548, 2008 | 86 | 2008 |
| Neuronal ubiquitin homeostasis J Hallengren, PC Chen, SM Wilson Cell biochemistry and biophysics 67, 67-73, 2013 | 73 | 2013 |
| Hypotriglyceridemic effect of Anka (a fermented rice product of Monascus sp.) in rats IK Wang, SY Lin-Shiau, PC Chen, JK Lin Journal of agricultural and food chemistry 48 (8), 3183-3189, 2000 | 53 | 2000 |
| Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction. JH Vaden, BJ Bhattacharyya, PC Chen, JA Watson, AG Marshall, ... Molecular Neurodegeneration 10 (3), doi:10.1186/1750-1326-10-3, 2015 | 49 | 2015 |
| Sequential elution interactome analysis of the mind bomb 1 ubiquitin ligase reveals a novel role in dendritic spine outgrowth J Mertz, H Tan, V Pagala, B Bai, PC Chen, Y Li, JH Cho, T Shaw, X Wang, ... Molecular & Cellular Proteomics 14 (7), 1898-1910, 2015 | 47 | 2015 |
| Transgenic rescue of ataxia mice reveals a male-specific sterility defect S Crimmins, M Sutovsky, PC Chen, A Huffman, C Wheeler, DA Swing, ... Developmental biology 325 (1), 33-42, 2009 | 43 | 2009 |
| Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy NM Badders, A Korff, HC Miranda, PK Vuppala, RB Smith, BJ Winborn, ... Nature medicine 24 (4), 427-437, 2018 | 39 | 2018 |
| Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits YN Jin, PC Chen, JA Watson, BJ Walters, SE Phillips, K Green, R Schmidt, ... PloS one 7 (10), e47884, 2012 | 34 | 2012 |
| Integrated approaches for analyzing U1-70K cleavage in Alzheimer’s disease B Bai, PC Chen, CM Hales, Z Wu, V Pagala, AA High, AI Levey, JJ Lah, ... Journal of proteome research 13 (11), 4526-4534, 2014 | 29 | 2014 |
| Quantitative proteomics to decipher ubiquitin signaling PC Chen, CH Na, J Peng Amino acids 43, 1049-1060, 2012 | 28 | 2012 |
| Distinct effects of ubiquitin overexpression on NMJ structure and motor performance in mice expressing catalytically inactive USP14 JH Vaden, JA Watson, AD Howard, PC Chen, JA Wilson, SM Wilson Frontiers in Molecular Neuroscience 8, 11, 2015 | 23 | 2015 |
Junmin Peng, Ph.D.St. Jude Children's Research HospitalVerified email at stjude.org
