Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation P Yi, S Melnyk, M Pogribna, IP Pogribny, RJ Hine, SJ James Journal of Biological Chemistry 275 (38), 29318-29323, 2000 | 814 | 2000 |
Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin O Kovalchuk, J Filkowski, J Meservy, Y Ilnytskyy, VP Tryndyak, ... Molecular cancer therapeutics 7 (7), 2152-2159, 2008 | 812 | 2008 |
Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas H Kutay, S Bai, J Datta, T Motiwala, I Pogribny, W Frankel, ST Jacob, ... Journal of cellular biochemistry 99 (3), 671-678, 2006 | 806 | 2006 |
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition Z Chen, AC Karaplis, SL Ackerman, IP Pogribny, S Melnyk, ... Human molecular genetics 10 (5), 433-444, 2001 | 794 | 2001 |
Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome SJ James, M Pogribna, IP Pogribny, S Melnyk, RJ Hine, JB Gibson, P Yi, ... The American journal of clinical nutrition 70 (4), 495-501, 1999 | 697 | 1999 |
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women RA Jacob, DM Gretz, PC Taylor, SJ James, IP Pogribny, BJ Miller, ... The Journal of nutrition 128 (7), 1204-1212, 1998 | 644 | 1998 |
Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology SJ James, S Melnyk, M Pogribna, IP Pogribny, MA Caudill The Journal of nutrition 132 (8), 2361S-2366S, 2002 | 450 | 2002 |
Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene YI Kim, IP Pogribny, AG Basnakian, JW Miller, J Selhub, SJ James, ... The American journal of clinical nutrition 65 (1), 46-52, 1997 | 426 | 1997 |
Alterations of microRNAs and their targets are associated with acquired resistance of MCF‐7 breast cancer cells to cisplatin IP Pogribny, JN Filkowski, VP Tryndyak, A Golubov, SI Shpyleva, ... International journal of cancer 127 (8), 1785-1794, 2010 | 424 | 2010 |
Transgenerational changes in the genome stability and methylation in pathogen-infected plants: (Virus-induced plant genome instability) A Boyko, P Kathiria, FJ Zemp, Y Yao, I Pogribny, I Kovalchuk Nucleic acids research 35 (5), 1714-1725, 2007 | 387 | 2007 |
Breaks in Genomic DNA and within the p53 Gene Are Associated with Hypomethylation in Livers of Folate/methyl-deficient Rats IP Pogribny, AG Basnakian, BJ Miller, NG Lopatina, LA Poirier, SJ James Cancer research 55 (9), 1894-1901, 1995 | 380 | 1995 |
Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine β-synthase heterozygous mice MA Caudill, JC Wang, S Melnyk, IP Pogribny, MD Collins, ... The Journal of nutrition 131 (11), 2811-2818, 2001 | 366 | 2001 |
Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location C Yauk, A Polyzos, A Rowan-Carroll, CM Somers, RW Godschalk, ... Proceedings of the National Academy of Sciences 105 (2), 605-610, 2008 | 365 | 2008 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation M Pogribna, S Melnyk, I Pogribny, A Chango, P Yi, SJ James The American Journal of Human Genetics 69 (1), 88-95, 2001 | 330 | 2001 |
E‐cadherin transcriptional down‐regulation by epigenetic and microRNA‐200 family alterations is related to mesenchymal and drug‐resistant phenotypes in human breast cancer cells VP Tryndyak, FA Beland, IP Pogribny International journal of cancer 126 (11), 2575-2583, 2010 | 277 | 2010 |
Measurement of Plasma and Intracellular S-Adenosylmethionine and S-Adenosylhomocysteine Utilizing Coulometric Electrochemical Detection: Alterations with … S Melnyk, M Pogribna, IP Pogribny, P Yi, SJ James Clinical chemistry 46 (2), 265-272, 2000 | 276 | 2000 |
Genome hypermethylation in Pinus silvestris of Chernobyl—a mechanism for radiation adaptation? O Kovalchuk, P Burke, A Arkhipov, N Kuchma, SJ James, I Kovalchuk, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 529 (1 …, 2003 | 274 | 2003 |
Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo I Koturbash, RE Rugo, CA Hendricks, J Loree, B Thibault, K Kutanzi, ... Oncogene 25 (31), 4267-4275, 2006 | 272 | 2006 |
DNA hypomethylation in the origin and pathogenesis of human diseases IP Pogribny, FA Beland Cellular and Molecular Life Sciences 66, 2249-2261, 2009 | 261 | 2009 |
A new HPLC method for the simultaneous determination of oxidized and reduced plasma aminothiols using coulometric electrochemical detection S Melnyk, M Pogribna, I Pogribny, RJ Hine, SJ James The Journal of nutritional biochemistry 10 (8), 490-497, 1999 | 260 | 1999 |