Kumar Sambamurti
Kumar Sambamurti
Professor of Neurosciences, Medical University of South Carolina
Підтверджена електронна адреса в musc.edu - Домашня сторінка
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
LM Refolo, MA Pappolla, B Malester, J LaFrancois, T Bryant-Thomas, ...
Neurobiology of disease 7 (4), 321-331, 2000
Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent
NH Greig, T Utsuki, DK Ingram, Y Wang, G Pepeu, C Scali, QS Yu, ...
Proceedings of the National Academy of Sciences 102 (47), 17213-17218, 2005
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration
A Salehi, JD Delcroix, PV Belichenko, K Zhan, C Wu, JS Valletta, ...
Neuron 51 (1), 29-42, 2006
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism
Y Li, TA Perry, MS Kindy, BK Harvey, D Tweedie, HW Holloway, K Powers, ...
Proceedings of the National Academy of Sciences 106 (4), 1285-1290, 2009
Butyrylcholinesterase: an important new target in Alzheimer's disease therapy
NH Greig, DK Lahiri, K Sambamurti
International Psychogeriatrics 14 (S1), 77-91, 2002
Glucagon‐like peptide‐1 decreases endogenous amyloid‐β peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron
TA Perry, DK Lahiri, K Sambamurti, D Chen, MP Mattson, JM Egan, ...
Journal of neuroscience research 72 (5), 603-612, 2003
Amyloid-β peptide levels in brain are inversely correlated with insulysin activity levels in vivo
BC Miller, EA Eckman, K Sambamurti, N Dobbs, KM Chow, CB Eckman, ...
Proceedings of the National Academy of Sciences 100 (10), 6221-6226, 2003
Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells
JP Anderson, FS Esch, PS Keim, K Sambamurti, I Lieberburg, NK Robakis
Neuroscience letters 128 (1), 126-128, 1991
High cholesterol‐induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice
L Thirumangalakudi, A Prakasam, R Zhang, H Bimonte‐Nelson, ...
Journal of neurochemistry 106 (1), 475-485, 2008
Reviews of evidence regarding interventions to reduce tobacco use and exposure to environmental tobacco smoke
DP Hopkins, PA Briss, CJ Ricard, CG Husten, VG Carande-Kulis, ...
American journal of preventive medicine 20 (2), 16-66, 2001
GLP-1 receptor stimulation reduces amyloid-β peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease
Y Li, KB Duffy, MA Ottinger, B Ray, JA Bailey, HW Holloway, D Tweedie, ...
Journal of Alzheimer's disease 19 (4), 1205-1219, 2010
Alzheimer's disease β-amyloid peptide is increased in mice deficient in endothelin-converting enzyme
EA Eckman, M Watson, L Marlow, K Sambamurti, CB Eckman
Journal of Biological Chemistry 278 (4), 2081-2084, 2003
Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat
AC Granholm, HA Bimonte-Nelson, AB Moore, ME Nelson, LR Freeman, ...
Journal of Alzheimer's Disease 14 (2), 133-145, 2008
Differential expression of cholesterol hydroxylases in Alzheimer's disease
J Brown, C Theisler, S Silberman, D Magnuson, N Gottardi-Littell, JM Lee, ...
Journal of Biological Chemistry 279 (33), 34674-34681, 2004
Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer’s disease
K Sambamurti, NH Greig, DK Lahiri
Neuromolecular medicine 1 (1), 1-31, 2002
Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer’s disease
R J Baranello, K L Bharani, V Padmaraju, N Chopra, D K Lahiri, N H Greig, ...
Current Alzheimer Research 12 (1), 32-46, 2015
Phenserine regulates translation of β-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development
KTY Shaw, T Utsuki, J Rogers, QS Yu, K Sambamurti, A Brossi, YW Ge, ...
Proceedings of the National Academy of Sciences 98 (13), 7605-7610, 2001
A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease
DK Lahiri, MR Farlow, K Sambamurti, NH Greig, E Giacobini, ...
Current drug targets 4 (2), 97-112, 2003
Current drug targets for Alzheimer's disease treatment
DK Lahiri, MR Farlow, NH Greig, K Sambamurti
Drug Development Research 56 (3), 267-281, 2002
Resolution of inflammation is altered in Alzheimer's disease
X Wang, M Zhu, E Hjorth, V Cortés-Toro, H Eyjolfsdottir, C Graff, ...
Alzheimer's & Dementia 11 (1), 40-50. e2, 2015
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