Decrypting the information exchange pathways across the spliceosome machinery A Saltalamacchia, L Casalino, J Borisek, VS Batista, I Rivalta, ... Journal of the American Chemical Society 142 (18), 8403-8411, 2020 | 35 | 2020 |
Allosteric cross-talk among spike’s receptor-binding domain mutations of the SARS-CoV-2 South African variant triggers an effective hijacking of human cell receptor A Spinello, A Saltalamacchia, J Borišek, A Magistrato The Journal of Physical Chemistry Letters 12 (25), 5987-5993, 2021 | 32 | 2021 |
Peptide inhibitors of bacterial protein synthesis with broad spectrum and SbmA-independent bactericidal activity against clinical pathogens M Mardirossian, R Sola, B Beckert, E Valencic, DWP Collis, J Borišek, ... Journal of medicinal chemistry 63 (17), 9590-9602, 2020 | 31 | 2020 |
Senescent cells as promising targets to tackle age-related diseases E Prašnikar, J Borišek, A Perdih Ageing Research Reviews 66, 101251, 2021 | 30 | 2021 |
The CWB2 cell wall-anchoring module is revealed by the crystal structures of the Clostridium difficile cell wall proteins Cwp8 and Cwp6 A Usenik, M Renko, M Mihelič, N Lindič, J Borišek, A Perdih, G Pretnar, ... Structure 25 (3), 514-521, 2017 | 30 | 2017 |
Disclosing the impact of carcinogenic SF3b mutations on pre-mRNA recognition via all-atom simulations J Borišek, A Saltalamacchia, A Gallì, G Palermo, E Molteni, L Malcovati, ... Biomolecules 9 (10), 633, 2019 | 29 | 2019 |
Exploiting cryo-EM structural information and all-atom simulations to decrypt the molecular mechanism of splicing modulators J Borisek, A Saltalamacchia, A Spinello, A Magistrato Journal of Chemical Information and Modeling 60 (5), 2510-2521, 2019 | 29 | 2019 |
All-atom simulations decrypt the molecular terms of RNA catalysis in the exon-ligation step of the spliceosome J Borišek, A Magistrato ACS Catalysis 10 (9), 5328-5334, 2020 | 28 | 2020 |
Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors J Borisek, M Vizovisek, P Sosnowski, B Turk, D Turk, B Mohar, M Novic Journal of medicinal chemistry 58 (17), 6928-6937, 2015 | 27 | 2015 |
Atomic-level mechanism of Pre-mRNA splicing in health and disease J Borisek, L Casalino, A Saltalamacchia, SG Mays, L Malcovati, ... Accounts of Chemical Research 54 (1), 144-154, 2020 | 26 | 2020 |
Molecular basis for functional diversity among microbial Nep1-like proteins T Lenarčič, K Pirc, V Hodnik, I Albert, J Borišek, A Magistrato, ... PLoS pathogens 15 (9), e1007951, 2019 | 24 | 2019 |
The comparison of docking search algorithms and scoring functions: an overview and case studies M Novič, T Tibaut, M Anderluh, J Borišek, T Tomašič Methods and algorithms for molecular docking-based drug design and discovery …, 2016 | 16 | 2016 |
An oomycete NLP cytolysin forms transient small pores in lipid membranes K Pirc, LA Clifton, N Yilmaz, A Saltalamacchia, M Mally, T Snoj, ... Science Advances 8 (10), eabj9406, 2022 | 13 | 2022 |
A Water-Assisted Catalytic Mechanism in Glycoside Hydrolases Demonstrated on the Staphylococcus aureus Autolysin E J Borišek, S Pintar, M Ogrizek, D Turk, A Perdih, M Novič ACS Catalysis 8 (5), 4334-4345, 2018 | 13 | 2018 |
Mechanistic interpretation of artificial neural network‐based QSAR model for prediction of cathepsin K inhibition potency J Borišek, V Drgan, N Minovski, M Novič Journal of Chemometrics 28 (4), 272-281, 2014 | 11 | 2014 |
Computing metal‐binding proteins for therapeutic benefit A Spinello, J Borišek, M Pavlin, P Janoš, A Magistrato ChemMedChem 16 (13), 2034-2049, 2021 | 10 | 2021 |
Nep1-like proteins as a target for plant pathogen control K Pirc, V Hodnik, T Snoj, T Lenarčič, S Caserman, M Podobnik, H Böhm, ... PLoS Pathogens 17 (4), e1009477, 2021 | 10 | 2021 |
Investigating the molecular mechanism of H3B-8800: a splicing modulator inducing preferential lethality in spliceosome-mutant cancers A Spinello, J Borišek, L Malcovati, A Magistrato International Journal of Molecular Sciences 22 (20), 11222, 2021 | 9 | 2021 |
Comparison of in silico tools for binding site prediction applied for structure-based design of autolysin inhibitors T Tibaut, J Borišek, M Novič, D Turk SAR and QSAR in Environmental Research 27 (7), 573-587, 2016 | 9 | 2016 |
Establishing the catalytic and regulatory mechanism of RNA‐based machineries J Borišek, J Aupič, A Magistrato Wiley Interdisciplinary Reviews: Computational Molecular Science 13 (3), e1643, 2023 | 8 | 2023 |