| Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase DP Hanger, K Hughes, JR Woodgett, JP Brion, BH Anderton Neuroscience letters 147 (1), 58-62, 1992 | 797 | 1992 |
| Tau phosphorylation: the therapeutic challenge for neurodegenerative disease DP Hanger, BH Anderton, W Noble Trends in molecular medicine 15 (3), 112-119, 2009 | 783 | 2009 |
| Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells S Lovestone, CH Reynolds, D Latimer, DR Davis, BH Anderton, JM Gallo, ... Current Biology 4 (12), 1077-1086, 1994 | 583 | 1994 |
| New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament‐tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry DP Hanger, JC Betts, TLF Loviny, WP Blackstock, BH Anderton Journal of neurochemistry 71 (6), 2465-2476, 1998 | 409 | 1998 |
| Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis DP Hanger, HL Byers, S Wray, KY Leung, MJ Saxton, A Seereeram, ... Journal of Biological Chemistry 282 (32), 23645-23654, 2007 | 392 | 2007 |
| Physiological release of endogenous tau is stimulated by neuronal activity AM Pooler, EC Phillips, DHW Lau, W Noble, DP Hanger EMBO reports 14 (4), 389-394, 2013 | 372 | 2013 |
| Roles of tau protein in health and disease T Guo, W Noble, DP Hanger Acta neuropathologica 133 (5), 665-704, 2017 | 363 | 2017 |
| Astrocytes are important mediators of A β-induced neurotoxicity and tau phosphorylation in primary culture CJ Garwood, AM Pooler, J Atherton, DP Hanger, W Noble Cell death & disease 2 (6), e167-e167, 2011 | 259 | 2011 |
| Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cγ1, Grb2, and Src family kinases CH Reynolds, CJ Garwood, S Wray, C Price, S Kellie, T Perera, ... Journal of Biological Chemistry 283 (26), 18177-18186, 2008 | 226 | 2008 |
| The importance of tau phosphorylation for neurodegenerative diseases W Noble, DP Hanger, CCJ Miller, S Lovestone Frontiers in neurology 4, 83, 2013 | 214 | 2013 |
| Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule‐binding repeat domains as demonstrated by new specific … R De Silva, T Lashley, G Gibb, D Hanger, A Hope, A Reid, ... Neuropathology and applied neurobiology 29 (3), 288-302, 2003 | 206 | 2003 |
| Induction of neuronal death by α‐synuclein AR Saha, NN Ninkina, DP Hanger, BH Anderton, AM Davies, ... European Journal of Neuroscience 12 (8), 3073-3077, 2000 | 196 | 2000 |
| Parkinson's disease α-synuclein mutations exhibit defective axonal transport in cultured neurons AR Saha, J Hill, MA Utton, AA Asuni, S Ackerley, AJ Grierson, CC Miller, ... Journal of cell science 117 (7), 1017-1024, 2004 | 187 | 2004 |
| Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase P Derkinderen, TME Scales, DP Hanger, KY Leung, HL Byers, MA Ward, ... Journal of Neuroscience 25 (28), 6584-6593, 2005 | 182 | 2005 |
| Collapsin response mediator protein‐2 hyperphosphorylation is an early event in Alzheimer’s disease progression AR Cole, W Noble, L Aalten, F Plattner, R Meimaridou, D Hogan, M Taylor, ... Journal of neurochemistry 103 (3), 1132-1144, 2007 | 175 | 2007 |
| Tau in Alzheimer neurofibrillary tangles. N-and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal … JP Brion, DP Hanger, MT Bruce, AM Couck, J Flament-Durand, ... Biochemical journal 273 (1), 127-133, 1991 | 169 | 1991 |
| Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin I Cuchillo‐Ibanez, A Seereeram, HL Byers, KY Leung, MA Ward, ... The FASEB Journal 22 (9), 3186-3195, 2008 | 163 | 2008 |
| A role for tau at the synapse in Alzheimer's disease pathogenesis AM Pooler, W Noble, DP Hanger Neuropharmacology 76, 1-8, 2014 | 157 | 2014 |
| Molecular motors implicated in the axonal transport of tau and α-synuclein MA Utton, WJ Noble, JE Hill, BH Anderton, DP Hanger Journal of cell science 118 (20), 4645-4654, 2005 | 147 | 2005 |
| The ER-mitochondria tethering complex VAPB-PTPIP51 regulates autophagy P Gomez-Suaga, S Paillusson, R Stoica, W Noble, DP Hanger, CCJ Miller Current Biology 27 (3), 371-385, 2017 | 144 | 2017 |
