|Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase|
DP Hanger, K Hughes, JR Woodgett, JP Brion, BH Anderton
Neuroscience letters 147 (1), 58-62, 1992
|Tau phosphorylation: the therapeutic challenge for neurodegenerative disease|
DP Hanger, BH Anderton, W Noble
Trends in molecular medicine 15 (3), 112-119, 2009
|Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells|
S Lovestone, CH Reynolds, D Latimer, DR Davis, BH Anderton, JM Gallo, ...
Current Biology 4 (12), 1077-1086, 1994
|New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament‐tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry|
DP Hanger, JC Betts, TLF Loviny, WP Blackstock, BH Anderton
Journal of neurochemistry 71 (6), 2465-2476, 1998
|Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis|
DP Hanger, HL Byers, S Wray, KY Leung, MJ Saxton, A Seereeram, ...
Journal of Biological Chemistry 282 (32), 23645-23654, 2007
|Physiological release of endogenous tau is stimulated by neuronal activity|
AM Pooler, EC Phillips, DHW Lau, W Noble, DP Hanger
EMBO reports 14 (4), 389-394, 2013
|Roles of tau protein in health and disease|
T Guo, W Noble, DP Hanger
Acta neuropathologica 133 (5), 665-704, 2017
|Astrocytes are important mediators of A β-induced neurotoxicity and tau phosphorylation in primary culture|
CJ Garwood, AM Pooler, J Atherton, DP Hanger, W Noble
Cell death & disease 2 (6), e167-e167, 2011
|Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cγ1, Grb2, and Src family kinases|
CH Reynolds, CJ Garwood, S Wray, C Price, S Kellie, T Perera, ...
Journal of Biological Chemistry 283 (26), 18177-18186, 2008
|The importance of tau phosphorylation for neurodegenerative diseases|
W Noble, DP Hanger, CCJ Miller, S Lovestone
Frontiers in neurology 4, 83, 2013
|Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule‐binding repeat domains as demonstrated by new specific …|
R De Silva, T Lashley, G Gibb, D Hanger, A Hope, A Reid, ...
Neuropathology and applied neurobiology 29 (3), 288-302, 2003
|Induction of neuronal death by α‐synuclein|
AR Saha, NN Ninkina, DP Hanger, BH Anderton, AM Davies, ...
European Journal of Neuroscience 12 (8), 3073-3077, 2000
|Parkinson's disease α-synuclein mutations exhibit defective axonal transport in cultured neurons|
AR Saha, J Hill, MA Utton, AA Asuni, S Ackerley, AJ Grierson, CC Miller, ...
Journal of cell science 117 (7), 1017-1024, 2004
|Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase|
P Derkinderen, TME Scales, DP Hanger, KY Leung, HL Byers, MA Ward, ...
Journal of Neuroscience 25 (28), 6584-6593, 2005
|Collapsin response mediator protein‐2 hyperphosphorylation is an early event in Alzheimer’s disease progression|
AR Cole, W Noble, L Aalten, F Plattner, R Meimaridou, D Hogan, M Taylor, ...
Journal of neurochemistry 103 (3), 1132-1144, 2007
|Tau in Alzheimer neurofibrillary tangles. N-and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal …|
JP Brion, DP Hanger, MT Bruce, AM Couck, J Flament-Durand, ...
Biochemical journal 273 (1), 127-133, 1991
|Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin|
I Cuchillo‐Ibanez, A Seereeram, HL Byers, KY Leung, MA Ward, ...
The FASEB Journal 22 (9), 3186-3195, 2008
|A role for tau at the synapse in Alzheimer's disease pathogenesis|
AM Pooler, W Noble, DP Hanger
Neuropharmacology 76, 1-8, 2014
|Molecular motors implicated in the axonal transport of tau and α-synuclein|
MA Utton, WJ Noble, JE Hill, BH Anderton, DP Hanger
Journal of cell science 118 (20), 4645-4654, 2005
|The ER-mitochondria tethering complex VAPB-PTPIP51 regulates autophagy|
P Gomez-Suaga, S Paillusson, R Stoica, W Noble, DP Hanger, CCJ Miller
Current Biology 27 (3), 371-385, 2017