Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death SJ Dixon, GE Winter, LS Musavi, ED Lee, B Snijder, M Rebsamen, ... ACS chemical biology 10 (7), 1604-1609, 2015 | 746 | 2015 |
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1 M Rebsamen, L Pochini, T Stasyk, MEG De Araújo, M Galluccio, ... Nature 519 (7544), 477-481, 2015 | 684 | 2015 |
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ... Nature immunology 11 (1), 63-69, 2010 | 657 | 2010 |
TRADD protein is an essential component of the RIG-like helicase antiviral pathway MC Michallet, E Meylan, MA Ermolaeva, J Vazquez, M Rebsamen, ... Immunity 28 (5), 651-661, 2008 | 385 | 2008 |
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF‐κB M Rebsamen, LX Heinz, E Meylan, MC Michallet, K Schroder, K Hofmann, ... EMBO reports 10 (8), 916-922, 2009 | 383 | 2009 |
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis A Fauster, M Rebsamen, KVM Huber, JW Bigenzahn, A Stukalov, ... Cell death & disease 6 (5), e1767-e1767, 2015 | 193 | 2015 |
NLRC5 deficiency selectively impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells F Staehli, K Ludigs, LX Heinz, Q Seguin-Estevez, I Ferrero, M Braun, ... The Journal of Immunology 188 (8), 3820-3828, 2012 | 170 | 2012 |
LZTR1 is a regulator of RAS ubiquitination and signaling JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ... Science 362 (6419), 1171-1177, 2018 | 163 | 2018 |
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9 LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ... Nature 581 (7808), 316-322, 2020 | 133 | 2020 |
A reversible gene trap collection empowers haploid genetics in human cells T Bürckstümmer, C Banning, P Hainzl, R Schobesberger, C Kerzendorfer, ... Nature methods 10 (10), 965-971, 2013 | 114 | 2013 |
LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning HLA Filipek PA, de Araujo MEG, Vogel GF, De Smet CH, Eberharter D, Rebsamen ... J Cell Biol, 2017 | 104 | 2017 |
The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity LX Heinz, CL Baumann, MS Köberlin, B Snijder, R Gawish, G Shui, ... Cell Reports 11 (12), 1919-1928, 2015 | 98 | 2015 |
The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases M Rebsamen, E Meylan, J Curran, J Tschopp Cell Death & Differentiation 15 (11), 1804-1811, 2008 | 89 | 2008 |
Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import E Girardi, G Agrimi, U Goldmann, G Fiume, S Lindinger, V Sedlyarov, ... Nature communications 11 (1), 6145, 2020 | 87 | 2020 |
NLRX1/NOD5 deficiency does not affect MAVS signalling M Rebsamen, J Vazquez, A Tardivel, G Guarda, J Curran, J Tschopp Cell Death & Differentiation 18 (8), 1387-1387, 2011 | 86 | 2011 |
The bicarbonate transporter SLC4A7 plays a key role in macrophage phagosome acidification V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ... Cell host & microbe 23 (6), 766-774. e5, 2018 | 74 | 2018 |
SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1 M Rebsamen, G Superti-Furga Autophagy 12 (6), 1061-1062, 2016 | 39 | 2016 |
A time-resolved molecular map of the macrophage response to VSV infection Kandasamy RK, Vladimir GI, Snijder B, Müller AC, Rebsamen M, Bigenzahn JW ... npj Systems Biology and Applications, 2016 | 36 | 2016 |
A substrate‐based ontology for human solute carriers E Meixner, U Goldmann, V Sedlyarov, S Scorzoni, M Rebsamen, E Girardi, ... Molecular Systems Biology 16 (7), e9652, 2020 | 35 | 2020 |
Insights into the transport side of the human SLC38A9 transceptor M Scalise, M Galluccio, L Pochini, J Cosco, M Trotta, M Rebsamen, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1861 (9), 1558-1567, 2019 | 32 | 2019 |