Peter A. Nigrovic, M.D.
Peter A. Nigrovic, M.D.
Harvard Medical School
Підтверджена електронна адреса в bwh.harvard.edu - Домашня сторінка
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Platelets amplify inflammation in arthritis via collagen-dependent microparticle production
E Boilard, PA Nigrovic, K Larabee, GFM Watts, JS Coblyn, ME Weinblatt, ...
Science 327 (5965), 580-583, 2010
9152010
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
AC Bulua, A Simon, R Maddipati, M Pelletier, H Park, KY Kim, MN Sack, ...
Journal of Experimental Medicine 208 (3), 519-533, 2011
6272011
Anakinra as first‐line disease‐modifying therapy in systemic juvenile idiopathic arthritis: report of forty‐six patients from an international multicenter series
PA Nigrovic, M Mannion, FHM Prince, A Zeft, CE Rabinovich, ...
Arthritis & rheumatism 63 (2), 545-555, 2011
3762011
2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children …
S Ringold, PF Weiss, T Beukelman, EM DeWitt, NT Ilowite, Y Kimura, ...
Arthritis & Rheumatism 65 (10), 2499-2512, 2013
3082013
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
A Hinks, J Cobb, MC Marion, S Prahalad, M Sudman, J Bowes, P Martin, ...
Nature genetics 45 (6), 664, 2013
2822013
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
DA Rao, MF Gurish, JL Marshall, K Slowikowski, CY Fonseka, Y Liu, ...
Nature 542 (7639), 110-114, 2017
2552017
Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation
LH Boudreau, AC Duchez, N Cloutier, D Soulet, N Martin, J Bollinger, ...
Blood, The Journal of the American Society of Hematology 124 (14), 2173-2183, 2014
2542014
Neutrophil-derived leukotriene B4 is required for inflammatory arthritis
M Chen, BK Lam, Y Kanaoka, PA Nigrovic, LP Audoly, KF Austen, ...
The Journal of experimental medicine 203 (4), 837-842, 2006
2512006
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity
ME Ackerman, M Crispin, X Yu, K Baruah, AW Boesch, DJ Harvey, ...
The Journal of clinical investigation 123 (5), 2183-2192, 2013
2202013
Aggregatibacter actinomycetemcomitans–induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis
MF Konig, L Abusleme, J Reinholdt, RJ Palmer, RP Teles, K Sampson, ...
Science translational medicine 8 (369), 369ra176-369ra176, 2016
2082016
Particularities of the vasculature can promote the organ specificity of autoimmune attack
BA Binstadt, PR Patel, H Alencar, PA Nigrovic, DM Lee, U Mahmood, ...
Nature immunology 7 (3), 284-292, 2006
1872006
Genetic inversion in mast cell-deficient Wsh mice interrupts corin and manifests as hematopoietic and cardiac aberrancy
PA Nigrovic, DHD Gray, T Jones, J Hallgren, FC Kuo, B Chaletzky, ...
The American journal of pathology 173 (6), 1693-1701, 2008
1862008
Synovial mast cells: role in acute and chronic arthritis
PA Nigrovic, DM Lee
Immunological reviews 217 (1), 19-37, 2007
1812007
Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes
K Shin, PA Nigrovic, J Crish, E Boilard, HP McNeil, KS Larabee, R Adachi, ...
The Journal of Immunology 182 (1), 647-656, 2009
1742009
Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1
PA Nigrovic, BA Binstadt, PA Monach, A Johnsen, M Gurish, Y Iwakura, ...
Proceedings of the National Academy of Sciences 104 (7), 2325-2330, 2007
1722007
Platelets: active players in the pathogenesis of arthritis and SLE
E Boilard, P Blanco, PA Nigrovic
Nature Reviews Rheumatology 8 (9), 534, 2012
1702012
Consensus treatment plans for new‐onset systemic juvenile idiopathic arthritis
EM Dewitt, Y Kimura, T Beukelman, PA Nigrovic, K Onel, S Prahalad, ...
Arthritis care & research 64 (7), 1001-1010, 2012
1592012
The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle‐associated immune complexes
N Cloutier, S Tan, LH Boudreau, C Cramb, R Subbaiah, L Lahey, A Albert, ...
EMBO molecular medicine 5 (2), 235-249, 2013
1542013
Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis
V Romero, J Fert-Bober, PA Nigrovic, E Darrah, UJ Haque, DM Lee, ...
Science translational medicine 5 (209), 209ra150-209ra150, 2013
1502013
Mast cells in inflammatory arthritis
PA Nigrovic, DM Lee
Arthritis Res Ther 7 (1), 1, 2004
1482004
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